CLN3 Deficient Cells Display Defects in the ARF1-Cdc42 Pathway and Actin-Dependent Events

Role of Small GTPase Protein Rac1 in Cardiovascular Diseases

(2013) Nicola Ferri et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

CLN3 Loss Disturbs Membrane Microdomain Properties and Protein Transport in Brain Endothelial Cells

(2013) L. Tecedor et al.   JOURNAL OF NEUROSCIENCE

Alterations in ROS Activity and Lysosomal pH Account for Distinct Patterns of Macroautophagy in LINCL and JNCL Fibroblasts

(2013) José Manuel Vidal-Donet et al.   PLoS One

The juvenile Batten disease protein, CLN3, and its role in regulating anterograde and retrograde post-Golgi trafficking

(2012) Susan L Cotman et al.   Clinical Lipidology

Effect of Robo4 on Retinal Endothelial Permeability

(2012) Yan Cheng et al.   CURRENT EYE RESEARCH

The role of small GTPases in neuronal morphogenesis and polarity

(2012) Christian Gonzalez-Billault et al.   Cytoskeleton

GBF1 bears a novel phosphatidylinositol-phosphate binding module, BP3K, to link PI3Kγ activity with Arf1 activation involved in GPCR-mediated neutrophil chemotaxis and superoxide production

(2012) Yuichi Mazaki et al.   MOLECULAR BIOLOGY OF THE CELL

The yeast Batten disease orthologue Btn1 controls endosome–Golgi retrograde transport via SNARE assembly

(2011) Rachel Kama et al.   JOURNAL OF CELL BIOLOGY

Juvenile neuronal ceroid lipofuscinosis: clinical course and genetic studies in Spanish patients

(2011) María-Socorro Pérez-Poyato et al.   JOURNAL OF INHERITED METABOLIC DISEASE

A novel interaction of CLN3 with nonmuscle myosin-IIB and defects in cell motility of Cln3−/− cells

(2010) Amanda L. Getty et al.   EXPERIMENTAL CELL RESEARCH

PAK1 as a therapeutic target

(2010) Julia V Kichina et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Cdc42 Regulates Microtubule-Dependent Golgi Positioning

(2010) Heidi Hehnly et al.   TRAFFIC

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

(2009) Steven A. Titus et al.   ANALYTICAL BIOCHEMISTRY

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

(2009) Massimiliano Mazzone et al.   CELL

S. pombe btn1, the orthologue of the Batten disease gene CLN3, is required for vacuole protein sorting of Cpy1p and Golgi exit of Vps10p

(2009) S. Codlin et al.   JOURNAL OF CELL SCIENCE

Retrograde Shiga Toxin Trafficking Is Regulated by ARHGAP21 and Cdc42

(2009) Heidi Hehnly et al.   MOLECULAR BIOLOGY OF THE CELL

Analysis of Endocytic Pathways in Drosophila Cells Reveals a Conserved Role for GBF1 in Internalization via GEECs

(2009) Gagan D. Gupta et al.   PLoS One

Novel interactions of CLN3 protein link Batten disease to dysregulation of fodrin–Na+, K+ ATPase complex

(2008) Kristiina Uusi-Rauva et al.   EXPERIMENTAL CELL RESEARCH

JNCL patients show marked brain volume alterations on longitudinal MRI in adolescence

(2008) T. H. Autti et al.   JOURNAL OF NEUROLOGY

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

btn1 Affects Endocytosis, Polarization of Sterol-Rich Membrane Domains and Polarized Growth in Schizosaccharomyces pombe

(2008) Sandra Codlin et al.   TRAFFIC

Loss of the Batten Disease Gene CLN3 Prevents Exit from the TGN of the Mannose 6-Phosphate Receptor

(2008) Daniel J Metcalf et al.   TRAFFIC