The role of small GTPases in neuronal morphogenesis and polarity

GEFT, A Rho Family Guanine Nucleotide Exchange Factor, Regulates Lens Differentiation through a Rac1-Mediated Mechanism

(2012) D. C. Mitchell et al.   CURRENT MOLECULAR MEDICINE

Dock3 Stimulates Axonal Outgrowth via GSK-3 -Mediated Microtubule Assembly

(2012) K. Namekata et al.   JOURNAL OF NEUROSCIENCE

Microtubule-associated Protein 1B (MAP1B) Is Required for Dendritic Spine Development and Synaptic Maturation

(2011) Elena Tortosa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RhoG/ELMO1/Dock180 Signaling Module Is Required for Spine Morphogenesis in Hippocampal Neurons

(2011) Jeong-Yoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PDZ-RhoGEF ubiquitination by Cullin3–KLHL20 controls neurotrophin-induced neurite outgrowth

(2011) Mei-Yao Lin et al.   JOURNAL OF CELL BIOLOGY

Structural Model for p75NTR–TrkA Intracellular Domain Interaction: A Combined FRET and Bioinformatics Study

(2011) María Florencia Iacaruso et al.   JOURNAL OF MOLECULAR BIOLOGY

Control of neurite outgrowth by RhoA inactivation

(2011) Chan-Young Jeon et al.   JOURNAL OF NEUROCHEMISTRY

Coup d’œil sur les petites GTPases Rho

(2011) Martin Primeau et al.   M S-MEDECINE SCIENCES

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Cytokinesis remnants define first neuronal asymmetry in vivo

(2011) Giulia Pollarolo et al.   NATURE NEUROSCIENCE

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

(2011) Rafael Garcia-Mata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptional Regulation of Neuronal Polarity and Morphogenesis in the Mammalian Brain

(2011) Luis de la Torre-Ubieta et al.   NEURON

Proneural Transcription Factors Regulate Different Steps of Cortical Neuron Migration through Rnd-Mediated Inhibition of RhoA Signaling

(2011) Emilie Pacary et al.   NEURON

Dynamics of the Rho-family small GTPases in actin regulation and motility

(2011) Désirée Spiering et al.   Cell Adhesion & Migration

Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1

(2010) Bingke Yu et al.   CELL

The role of C. elegans Ena/VASP homolog UNC-34 in neuronal polarity and motility

(2010) Tinya Fleming et al.   DEVELOPMENTAL BIOLOGY

p190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells

(2010) Chan-Young Jeon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Spatio-temporal Rho GTPase signaling - where are we now?

(2010) O. Pertz   JOURNAL OF CELL SCIENCE

Neurite outgrowth from PC12 cells by basic fibroblast growth factor (bFGF) is mediated by RhoA inactivation through p190RhoGAP and ARAP3

(2010) Chan-Young Jeon et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Control of Postnatal Apoptosis in the Neocortex byRhoA-Subfamily GTPases Determines Neuronal Density

(2010) H. Sanno et al.   JOURNAL OF NEUROSCIENCE

Evidence for the Involvement of Lfc and Tctex-1 in Axon Formation

(2010) C. Conde et al.   JOURNAL OF NEUROSCIENCE

Rac1 Regulates Neuronal Polarization through the WAVE Complex

(2010) S. Tahirovic et al.   JOURNAL OF NEUROSCIENCE

A Role for RhoB in Synaptic Plasticity and the Regulation of Neuronal Morphology

(2010) K. McNair et al.   JOURNAL OF NEUROSCIENCE

The Guanine Exchange Factor vav Controls Axon Growth and Guidance during Drosophila Development

(2010) M. Malartre et al.   JOURNAL OF NEUROSCIENCE

MAP1B Regulates Axonal Development by Modulating Rho-GTPase Rac1 Activity

(2010) Carolina Montenegro-Venegas et al.   MOLECULAR BIOLOGY OF THE CELL

Involvement of p114-RhoGEF and Lfc in Wnt-3a– and Dishevelled-Induced RhoA Activation and Neurite Retraction in N1E-115 Mouse Neuroblastoma Cells

(2010) Takuji Tsuji et al.   MOLECULAR BIOLOGY OF THE CELL

RHO GTPase Signaling for Axon Extension: Is Prenylation Important?

(2010) Filsy Samuel et al.   MOLECULAR NEUROBIOLOGY

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II

(2010) Ailish Murray et al.   Neural Development

The Transcription Factor Cux1 Regulates Dendritic Morphology of Cortical Pyramidal Neurons

(2010) Ning Li et al.   PLoS One

Rho GTPases and exocytosis: What are the molecular links?

(2010) Stéphane Ory et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

Rho and Ras GTPases in Axon Growth, Guidance, and Branching

(2010) A. Hall et al.   Cold Spring Harbor Perspectives in Biology

Establishment of Axon-Dendrite Polarity in Developing Neurons

(2009) Anthony P. Barnes et al.   Annual Review of Neuroscience

RhoBTB3: A Rho GTPase-Family ATPase Required for Endosome to Golgi Transport

(2009) Eric J. Espinosa et al.   CELL

Cellular signaling of Dock family proteins in neural function

(2009) Yuki Miyamoto et al.   CELLULAR SIGNALLING

Bric-a-Brac at the Golgi

(2009) Lydia Danglot et al.   DEVELOPMENTAL CELL

Essential role of Rac1 and Rac3 GTPases in neuronal development

(2009) Sara Corbetta et al.   FASEB JOURNAL

Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis

(2009) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling

(2009) A. Hajdo-Milasinovic et al.   JOURNAL OF CELL SCIENCE

The TC10-Exo70 Complex Is Essential for Membrane Expansion and Axonal Specification in Developing Neurons

(2009) S. Dupraz et al.   JOURNAL OF NEUROSCIENCE

Modulation of Rho Guanine Exchange Factor Lfc Activity by Protein Kinase A-Mediated Phosphorylation

(2009) D. Meiri et al.   MOLECULAR AND CELLULAR BIOLOGY

Kalirin loss results in cortical morphological alterations

(2009) Zhong Xie et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells

(2009) Andrée Gauthier-Fisher et al.   NATURE NEUROSCIENCE

The trip of the tip: understanding the growth cone machinery

(2009) Laura Anne Lowery et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Plasma membrane expansion: a neuron's Herculean task

(2009) Karl H. Pfenninger   NATURE REVIEWS NEUROSCIENCE

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

The C-Terminal Sequence of RhoB Directs Protein Degradation through an Endo-Lysosomal Pathway

(2009) Dolores Pérez-Sala et al.   PLoS One

AMPA receptor and GEF-H1/Lfc complex regulates dendritic spine development through RhoA signaling cascade

(2009) M.-G. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of neuronal polarity and plasticity – a renaissance for microtubules?

(2009) Casper C. Hoogenraad et al.   TRENDS IN CELL BIOLOGY

Neuronal Polarity

(2009) S. Tahirovic et al.   Cold Spring Harbor Perspectives in Biology

Phosphorylation of RhoGDI1 by p21-activated kinase 2 mediates basic fibroblast growth factor-stimulated neurite outgrowth in PC12 cells

(2008) Eun-Young Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rho-Kinase Phosphorylates PAR-3 and Disrupts PAR Complex Formation

(2008) Masanori Nakayama et al.   DEVELOPMENTAL CELL

Myosin II Activity Facilitates Microtubule Bundling in the Neuronal Growth Cone Neck

(2008) Dylan T. Burnette et al.   DEVELOPMENTAL CELL

Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes — Evidence for an autoregulatory mechanism

(2008) Jessica Berthold et al.   EXPERIMENTAL CELL RESEARCH

PX-RICS mediates ER-to-Golgi transport of the N-cadherin/ -catenin complex

(2008) T. Nakamura et al.   GENES & DEVELOPMENT

Coordination of Synaptic Adhesion with Dendritic Spine Remodeling by AF-6 and Kalirin-7

(2008) Z. Xie et al.   JOURNAL OF NEUROSCIENCE

Downregulation of Rho-GDI γ promotes differentiation of neural stem cells

(2008) Wei Lu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Neurogenin 2 controls cortical neuron migration through regulation of Rnd2

(2008) Julian Ik-Tsen Heng et al.   NATURE

Beyond polymer polarity: how the cytoskeleton builds a polarized cell

(2008) Rong Li et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A negative modulatory role for rho and rho-associated kinase signaling in delamination of neural crest cells

(2008) Maya Groysman et al.   Neural Development

Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network

(2008) O. C. Pertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rotenone-Induced Toxicity is Mediated by Rho-GTPases in Hippocampal Neurons

(2008) Monica Sanchez et al.   TOXICOLOGICAL SCIENCES

Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?

(2008) Jörg Birkenfeld et al.   TRENDS IN CELL BIOLOGY