Mycobacteria Counteract a TLR-Mediated Nitrosative Defense Mechanism in a Zebrafish Infection Model

Reprogramming Adult Schwann Cells to Stem Cell-like Cells by Leprosy Bacilli Promotes Dissemination of Infection

(2013) Toshihiro Masaki et al.   CELL

TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species

(2013) Francisco J. Roca et al.   CELL

Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system

(2013) M. van der Vaart et al.   Disease Models & Mechanisms

Cxcl8 (IL-8) Mediates Neutrophil Recruitment and Behavior in the Zebrafish Inflammatory Response

(2013) S. de Oliveira et al.   JOURNAL OF IMMUNOLOGY

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish

(2013) Qing Deng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

(2013) C. J. Cambier et al.   NATURE

Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

(2013) Philip M. Elks et al.   PLoS Pathogens

Outwitting Evolution: Fighting Drug-Resistant TB, Malaria, and HIV

(2012) Daniel E. Goldberg et al.   CELL

Neutrophils Exert Protection in the Early Tuberculous Granuloma by Oxidative Killing of Mycobacteria Phagocytosed from Infected Macrophages

(2012) Chao-Tsung Yang et al.   Cell Host & Microbe

Infection-Responsive Expansion of the Hematopoietic Stem and Progenitor Cell Compartment in Zebrafish Is Dependent upon Inducible Nitric Oxide

(2012) Christopher J. Hall et al.   Cell Stem Cell

Innate Immune Gene Polymorphisms in Tuberculosis

(2012) Abul K. Azad et al.   INFECTION AND IMMUNITY

Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5

(2012) Maria Buxadé et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mycobacterium tuberculosisWhiB4 regulates oxidative stress response to modulate survival and disseminationin vivo

(2012) Manbeena Chawla et al.   MOLECULAR MICROBIOLOGY

Resistance to First-Line Anti-TB Drugs Is Associated with Reduced Nitric Oxide Susceptibility in Mycobacterium tuberculosis

(2012) Jonna Idh et al.   PLoS One

Mycobacterium marinum Causes a Latent Infection that Can Be Reactivated by Gamma Irradiation in Adult Zebrafish

(2012) Mataleena Parikka et al.   PLoS Pathogens

Infection of Zebrafish Embryos with Intracellular Bacterial Pathogens

(2012) Erica L. Benard et al.   Jove-Journal of Visualized Experiments

Activation of hypoxia-inducible factor-1  (Hif-1 ) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

(2011) P. M. Elks et al.   BLOOD

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

(2011) E. J. M. Stoop et al.   Disease Models & Mechanisms

Redox homeostasis in mycobacteria: the key to tuberculosis control?

(2011) Ashwani Kumar et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Macrophages and control of granulomatous inflammation in tuberculosis

(2011) J L Flynn et al.   Mucosal Immunology

The challenge of new drug discovery for tuberculosis

(2011) Anil Koul et al.   NATURE

What the Myddosome structure tells us about the initiation of innate immunity

(2011) Nicholas J. Gay et al.   TRENDS IN IMMUNOLOGY

The Response of Mycobacterium Tuberculosis to Reactive Oxygen and Nitrogen Species

(2011) Martin I. Voskuil et al.   Frontiers in Microbiology

The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

(2010) David M. Tobin et al.   CELL

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

(2009) J. Muse Davis et al.   CELL

Mycobacterial survival strategies in the phagosome: defence against host stresses

(2009) Sabine Ehrt et al.   CELLULAR MICROBIOLOGY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Comparative analysis of zebrafish nos2a and nos2b genes

(2009) Sandrine Lepiller et al.   GENE

Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish

(2009) Catherine A. Loynes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components

(2009) Astrid M. van der Sar et al.   MOLECULAR IMMUNOLOGY

Tuberculous Granuloma Induction via Interaction of a Bacterial Secreted Protein with Host Epithelium

(2009) H. E. Volkman et al.   SCIENCE

The Role of Nitric Oxide in Mycobacterial Infections

(2009) Chul-Su Yang et al.   Immune Network

Tumor Necrosis Factor Signaling Mediates Resistance to Mycobacteria by Inhibiting Bacterial Growth and Macrophage Death

(2008) Hilary Clay et al.   IMMUNITY

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Differential contribution of neutrophilic granulocytes and macrophages to nitrosative stress in a host–parasite animal model

(2008) Maria Forlenza et al.   MOLECULAR IMMUNOLOGY

Mycobacterium tuberculosisexpresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite

(2008) Warren L. Lee et al.   MOLECULAR MICROBIOLOGY

Role of arginine metabolism in immunity and immunopathology

(2007) Elisa Peranzoni et al.   IMMUNOBIOLOGY