Verapamil Protects against Cartilage Degradation in Osteoarthritis by Inhibiting Wnt/β-Catenin Signaling
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Verapamil Protects against Cartilage Degradation in Osteoarthritis by Inhibiting Wnt/β-Catenin Signaling
Authors
Keywords
Chondrocytes, Osteoarthritis, Luciferase, Articular cartilage, Cell differentiation, Proteoglycans, Wnt signaling cascade, Growth plate
Journal
PLoS One
Volume 9, Issue 3, Pages e92699
Publisher
Public Library of Science (PLoS)
Online
2014-03-22
DOI
10.1371/journal.pone.0092699
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Physiology of Blood–Brain Interfaces in Relation to Brain Disposition of Small Compounds and Macromolecules
- (2013) N. Strazielle et al. MOLECULAR PHARMACEUTICS
- Dkk-1 promotes angiogenic responses and cartilage matrix proteinase secretion in synovial fibroblasts from osteoarthritic joints
- (2012) Lin-Hsiu Weng et al. ARTHRITIS AND RHEUMATISM
- Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis
- (2012) J. C. H. Leijten et al. ARTHRITIS AND RHEUMATISM
- Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia
- (2012) Stephany Corrêa et al. BMC CANCER
- WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways
- (2011) Giovanna Nalesso et al. JOURNAL OF CELL BIOLOGY
- Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis
- (2011) B.Y. Chan et al. OSTEOARTHRITIS AND CARTILAGE
- Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis
- (2011) Rhian S Thomas et al. ARTHRITIS RESEARCH & THERAPY
- Is Cartilage Matrix Breakdown an Appropriate Therapeutic Target in Osteoarthritis – Insights from Studies of Aggrecan and Collagen Proteolysis?
- (2010) Christopher B. Little et al. CURRENT DRUG TARGETS
- Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
- (2010) Taku Saito et al. NATURE MEDICINE
- Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome
- (2009) Yang Bian et al. HUMAN MOLECULAR GENETICS
- The Transcriptional Activity of Sox9 in Chondrocytes Is Regulated by RhoA Signaling and Actin Polymerization
- (2009) D. Kumar et al. MOLECULAR AND CELLULAR BIOLOGY
- Inhibition of β‐catenin signaling in articular chondrocytes results in articular cartilage destruction
- (2008) Mei Zhu et al. ARTHRITIS AND RHEUMATISM
- Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice
- (2008) Mei Zhu et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Wnt/β-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration
- (2008) Takahito Yuasa et al. LABORATORY INVESTIGATION
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started