Positive Feedback Regulation of Proliferation in Vascular Smooth Muscle Cells Stimulated by Lipopolysaccharide Is Mediated through the TLR 4/Rac1/Akt Pathway
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Title
Positive Feedback Regulation of Proliferation in Vascular Smooth Muscle Cells Stimulated by Lipopolysaccharide Is Mediated through the TLR 4/Rac1/Akt Pathway
Authors
Keywords
Toll-like receptors, Immune receptor signaling, Protein expression, AKT signaling cascade, Atherosclerosis, Inflammation, Cardiovascular diseases, Cell proliferation
Journal
PLoS One
Volume 9, Issue 3, Pages e92398
Publisher
Public Library of Science (PLoS)
Online
2014-03-26
DOI
10.1371/journal.pone.0092398
References
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- (2010) Y. Shen et al. INFECTION AND IMMUNITY
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- (2010) J. Brown et al. JOURNAL OF DENTAL RESEARCH
- Mechanisms of Vascular Smooth Muscle NADPH Oxidase 1 (Nox1) Contribution to Injury-Induced Neointimal Formation
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- Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells
- (2008) D. Meng et al. CARDIOVASCULAR RESEARCH
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- (2008) Athanasios Katsargyris et al. EXPERT OPINION ON THERAPEUTIC TARGETS
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