Positive Feedback Regulation of Proliferation in Vascular Smooth Muscle Cells Stimulated by Lipopolysaccharide Is Mediated through the TLR 4/Rac1/Akt Pathway

RACK1 promotes the proliferation, migration and invasion capacity of mouse hepatocellular carcinoma cell line in vitro probably by PI3K/Rac1 signaling pathway

(2013) Jun Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

HIF-1α activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells

(2013) Alexander Weidemann et al.   Cell Communication and Signaling

Inhibition of reactive oxygen species generation attenuates TLR4-mediated proinflammatory and proliferative phenotype of vascular smooth muscle cells

(2013) Yan Pi et al.   LABORATORY INVESTIGATION

TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice

(2012) Zhongyang Lu et al.   JOURNAL OF ENDOCRINOLOGY

Protective Role for TLR4 Signaling in Atherosclerosis Progression as Revealed by Infection with a Common Oral Pathogen

(2012) C. Hayashi et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide Induces Lung Fibroblast Proliferation through Toll-Like Receptor 4 Signaling and the Phosphoinositide3-Kinase-Akt Pathway

(2012) Zhengyu He et al.   PLoS One

PI3K p110α Isoform-Dependent Rho GTPase Rac1 Activation Mediates H2S-Promoted Endothelial Cell Migration via Actin Cytoskeleton Reorganization

(2012) Li-Jia Zhang et al.   PLoS One

Molecular Evolution and Structural Features of IRAK Family Members

(2012) Vijayakumar Gosu et al.   PLoS One

The Actin-Binding Protein Girdin and Its Akt-Mediated Phosphorylation Regulate Neointima Formation After Vascular Injury

(2011) Hiroshi Miyake et al.   CIRCULATION RESEARCH

Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes

(2011) Sridevi Devaraj et al.   CYTOKINE

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

RhoA and Rac1 Changes in the Atherosclerotic Lesions of WHHLMI Rabbits

(2011) Hiroshi Ohkawara et al.   Journal of Atherosclerosis and Thrombosis

Resveratrol inhibits migration and Rac1 activation in EGF- but not PDGF-activated vascular smooth muscle cells

(2011) Mario Kumerz et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Regulation of AKT Phosphorylation at Ser473 and Thr308 by Endoplasmic Reticulum Stress Modulates Substrate Specificity in a Severity Dependent Manner

(2011) Hong Wa Yung et al.   PLoS One

Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor

(2010) Jessica Perez et al.   BIOCHEMICAL JOURNAL

Toll-Like Receptor 2- and MyD88-Dependent Phosphatidylinositol 3-Kinase and Rac1 Activation Facilitates the Phagocytosis of Listeria monocytogenes by Murine Macrophages

(2010) Y. Shen et al.   INFECTION AND IMMUNITY

TLR-signaling Networks

(2010) J. Brown et al.   JOURNAL OF DENTAL RESEARCH

Mechanisms of Vascular Smooth Muscle NADPH Oxidase 1 (Nox1) Contribution to Injury-Induced Neointimal Formation

(2009) Moo Yeol Lee et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The insert region of the Rac GTPases is dispensable for activation of superoxide-producing NADPH oxidases

(2009) Kei Miyano et al.   BIOCHEMICAL JOURNAL

Toll-like receptor signaling in cell proliferation and survival

(2009) Xinyan Li et al.   CYTOKINE

IRAK-1 Contributes to Lipopolysaccharide-induced Reactive Oxygen Species Generation in Macrophages by Inducing NOX-1 Transcription and Rac1 Activation and Suppressing the Expression of Antioxidative Enzymes

(2009) Urmila Maitra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rac1 mediates sex difference in cardiac tumor necrosis factor-α expression via NADPH oxidase–ERK1/2/p38 MAPK pathway in endotoxemia

(2009) Huaqing Zhu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

PLC-γ1 and Rac1 Coregulate EGF-Induced Cytoskeleton Remodeling and Cell Migration

(2009) Siwei Li et al.   MOLECULAR ENDOCRINOLOGY

Rac1 regulates peptidoglycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages by activating the phosphatidylinositol 3-kinase/Akt pathway

(2009) Bing-Chang Chen et al.   MOLECULAR IMMUNOLOGY

Role of Smooth Muscle Cells in the Initiation and Early Progression of Atherosclerosis

(2008) Amanda C. Doran et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells

(2008) D. Meng et al.   CARDIOVASCULAR RESEARCH

Toll-like receptor modulation: A novel therapeutic strategy in cardiovascular disease?

(2008) Athanasios Katsargyris et al.   EXPERT OPINION ON THERAPEUTIC TARGETS