Increased Frequency of Tim-3 Expressing T Cells Is Associated with Symptomatic West Nile Virus Infection

Leukoreduction system chambers are an efficient, valid, and economic source of functional monocyte-derived dendritic cells and lymphocytes

(2013) Isabell A. Pfeiffer et al.   IMMUNOBIOLOGY

West Nile virus infection and immunity

(2013) Mehul S. Suthar et al.   NATURE REVIEWS MICROBIOLOGY

Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity

(2012) L. C. Ndhlovu et al.   BLOOD

Enhanced Tim3 Activity Improves Survival after Influenza Infection

(2012) J. L. Cho et al.   JOURNAL OF IMMUNOLOGY

Current practices and evaluation of screening solid organ donors for West Nile virus

(2012) R.J. Nett et al.   Transplant Infectious Disease

Tim-3-Expressing CD4+ and CD8+ T Cells in Human Tuberculosis (TB) Exhibit Polarized Effector Memory Phenotypes and Stronger Anti-TB Effector Functions

(2012) Yueqin Qiu et al.   PLoS Pathogens

Anti-TIM3 Antibody Promotes T Cell IFN- -Mediated Antitumor Immunity and Suppresses Established Tumors

(2011) S. F. Ngiow et al.   CANCER RESEARCH

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Association between HLA Class I and Class II Alleles and the Outcome of West Nile Virus Infection: An Exploratory Study

(2011) Marion C. Lanteri et al.   PLoS One

Host Genetic Risk Factors for West Nile Virus Infection and Disease Progression

(2011) Abigail W. Bigham et al.   PLoS One

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

(2010) Rachel H. McMahan et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Single-Chain HLA-A2 MHC Trimers That Incorporate an Immundominant Peptide Elicit Protective T Cell Immunity against Lethal West Nile Virus Infection

(2010) S. Kim et al.   JOURNAL OF IMMUNOLOGY

Persistence of West Nile Virus in the Central Nervous System and Periphery of Mice

(2010) Kim K. Appler et al.   PLoS One

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

(2009) Nobuhiro Nakamoto et al.   PLoS Pathogens

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

(2008) Nobuhiro Nakamoto et al.   GASTROENTEROLOGY

Interferon and Interferon‐Induced Chemokine Expression Is Associated with Control of Acute Viremia in West Nile Virus–Infected Blood Donors

(2008) Leslie H. Tobler et al.   JOURNAL OF INFECTIOUS DISEASES

Comprehensive Analysis of West Nile Virus–Specific T Cell Responses in Humans

(2008) Marion C. Lanteri et al.   JOURNAL OF INFECTIOUS DISEASES