A Network Pharmacology Approach to Understanding the Mechanisms of Action of Traditional Medicine: Bushenhuoxue Formula for Treatment of Chronic Kidney Disease
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Title
A Network Pharmacology Approach to Understanding the Mechanisms of Action of Traditional Medicine: Bushenhuoxue Formula for Treatment of Chronic Kidney Disease
Authors
Keywords
Drug discovery, Cytokine receptors, Chronic kidney disease, Epidermal growth factor, Protein interaction networks, Insulin-like growth factors, Cytokines, Herbs
Journal
PLoS One
Volume 9, Issue 3, Pages e89123
Publisher
Public Library of Science (PLoS)
Online
2014-03-06
DOI
10.1371/journal.pone.0089123
References
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Note: Only part of the references are listed.- Rutin (Quercetin Rutinoside) Induced Protein-Energy Malnutrition in Chronic Kidney Disease, but Quercetin Acted Beneficially
- (2013) Chiu-Lan Hsieh et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Beneficial therapeutic effect of Chinese herbal Bushen formula on CHB patients with mildly elevated alanine aminotransferase by down-regulating CD4+CD25+T cells
- (2013) Man Li et al. JOURNAL OF ETHNOPHARMACOLOGY
- Material Basis of Chinese Herbal Formulas Explored by Combining Pharmacokinetics with Network Pharmacology
- (2013) Lixia Pei et al. PLoS One
- Tanshinone IIA protects rabbits against LPS-induced disseminated intravascular coagulation (DIC)
- (2012) Liang-cai Wu et al. ACTA PHARMACOLOGICA SINICA
- Nephrotoxicity of Alternative Medicine Practice
- (2012) Valerie A. Luyckx ADVANCES IN CHRONIC KIDNEY DISEASE
- Metabolic Syndrome and Progression of Chronic Kidney Disease: A Systematic Review
- (2012) AMERICAN JOURNAL OF KIDNEY DISEASES
- Anti-obesity and hypolipidemic effects of Rheum undulatum in high-fat diet-fed C57BL/6 mice through protein tyrosine phosphatase 1B inhibition
- (2012) Woo-Jung Lee et al. BMB Reports
- β2-Adrenoceptor and insulin receptor expression in the skeletal muscle of streptozotocin induced diabetic rats: Antagonism by vitamin D3 and curcumin
- (2012) Serene Xavier et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Gene expression profiling in glomeruli of diabetic nephropathy rat
- (2012) Qian Zhang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- A Systems Biology Approach to Understanding the Mechanisms of Action of Chinese Herbs for Treatment of Cardiovascular Disease
- (2012) Bohui Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Application of dispersive solid-phase extraction and ultra-fast liquid chromatography–tandem quadrupole mass spectrometry in food additive residue analysis of red wine
- (2012) Xiao-Hong Chen et al. JOURNAL OF CHROMATOGRAPHY A
- Progress in Gammaglobulin Therapy for Immunodeficiency: From Subcutaneous to Intravenous Infusions and Back Again
- (2012) Richard L. Wasserman JOURNAL OF CLINICAL IMMUNOLOGY
- Prevalence of chronic kidney disease in China: a cross-sectional survey
- (2012) Luxia Zhang et al. LANCET
- Antidepressants for depression in stage 3–5 chronic kidney disease: a systematic review of pharmacokinetics, efficacy and safety with recommendations by European Renal Best Practice (ERBP)*
- (2012) Evi V. Nagler et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Tanshinone IIA Prevents Uric Acid Nephropathy in Rats through NF-κB Inhibition
- (2012) Xinlin Wu et al. PLANTA MEDICA
- Ameliorative Effects of Quercetin on Sodium Fluoride-Induced Oxidative Stress in Rat’s Kidney
- (2012) Seyed Mohammad Nabavi et al. RENAL FAILURE
- TGF-β Signaling via TAK1 Pathway: Role in Kidney Fibrosis
- (2012) Mary E. Choi et al. SEMINARS IN NEPHROLOGY
- Chapter 5: Network Biology Approach to Complex Diseases
- (2012) Dong-Yeon Cho et al. PLoS Computational Biology
- Focal Adhesion Kinase Signaling Mediates Acute Renal Injury Induced by Ischemia/Reperfusion
- (2011) Yu Qin et al. AMERICAN JOURNAL OF PATHOLOGY
- Targeting Endothelium-Pericyte Cross Talk by Inhibiting VEGF Receptor Signaling Attenuates Kidney Microvascular Rarefaction and Fibrosis
- (2011) Shuei-Liong Lin et al. AMERICAN JOURNAL OF PATHOLOGY
- Cardiovascular actions and therapeutic potential of tanshinone IIA
- (2011) Si Gao et al. ATHEROSCLEROSIS
- Curcumin Attenuates Lipopolysaccharide-Induced Renal Inflammation
- (2011) Fang Zhong et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Emodin Inhibits Proinflammatory Responses and Inactivates Histone Deacetylase 1 in Hypoxic Rheumatoid Synoviocytes
- (2011) Mi-Kyoung Ha et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Preventive Effects and Mechanisms of Rhein on Renal Interstitial Fibrosis in Obstructive Nephropathy
- (2011) Dongyuan He et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Curcumin Protects from Cardiac Reperfusion Damage by Attenuation of Oxidant Stress and Mitochondrial Dysfunction
- (2011) Alfredo González-Salazar et al. Cardiovascular Toxicology
- Rhein inhibits angiogenesis and the viability of hormone-dependent and -independent cancer cells under normoxic or hypoxic conditions in vitro
- (2011) Vivian E. Fernand et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Chronic Inflammatory Disorders and Accelerated Atherosclerosis: Chronic Kidney Disease
- (2011) Kaveh D. Navab et al. CURRENT PHARMACEUTICAL DESIGN
- Rhein protects against acetaminophen-induced hepatic and renal toxicity
- (2011) Yan-Ling Zhao et al. FOOD AND CHEMICAL TOXICOLOGY
- Identification of Essential Proteins Based on Edge Clustering Coefficient
- (2011) Jianxin Wang et al. IEEE-ACM Transactions on Computational Biology and Bioinformatics
- Simultaneous determination of 3,3′,4′,5,7-pentamethylquercetin and its possible metabolite 3,3′,4′,7-tetramethylquercetin in dog plasma by liquid chromatography–tandem mass spectrometry and its application to preclinical pharmacokinetic study
- (2011) Xiaomei Chen et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Optimized project of traditional Chinese medicine in treating chronic kidney disease stage 3: A multicenter double-blinded randomized controlled trial
- (2011) Yong-jun Wang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Expression of Focal Adhesion Proteins in the Developing Rat Kidney
- (2011) Sato Matsuura et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Phosphodiesterase 5 inhibitors attenuate renal tubular apoptosis after partial unilateral ureteral obstruction: An experimental study
- (2011) Turgay Akgül et al. KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
- Upregulation of MicroRNA-210 Regulates Renal Angiogenesis Mediated by Activation of VEGF Signaling Pathway under Ischemia/Perfusion Injury in vivo and in vitro
- (2011) Fen Liu et al. KIDNEY & BLOOD PRESSURE RESEARCH
- Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis
- (2011) Steven G. Coca et al. KIDNEY INTERNATIONAL
- Metabolomics Study on Quality Control and Discrimination of Three Curcuma Species based on Gas Chromatograph-Mass Spectrometry
- (2011) Zheng Xiang et al. PHYTOCHEMICAL ANALYSIS
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- (2011) Zhi-Mei Lv et al. PLoS One
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- (2010) Yongsheng Li et al. Journal of Huazhong University of Science and Technology-Medical Sciences
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- (2010) Yun Liu et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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- (2010) Peter Y. Chuang et al. KIDNEY INTERNATIONAL
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- (2010) VIVEKANAND JHA NEPHROLOGY
- DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs
- (2010) C. Knox et al. NUCLEIC ACIDS RESEARCH
- Vitamin D, chronic kidney disease and survival: a pluripotent hormone or just another bone drug?
- (2010) Patrick H. Biggar et al. PEDIATRIC NEPHROLOGY
- Renoprotective effect of Tanshinone IIA, an active component of Salvia miltiorrhiza, on rats with chronic kidney disease
- (2010) Young-Min Ahn et al. PHYTOTHERAPY RESEARCH
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- (2009) S. I. Berger et al. BIOINFORMATICS
- Protective Effect of Tanshinone IIA on the Early Stage of Experimental Diabetic Nephropathy
- (2009) Su Kang Kim et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Characterization and renal protective effect of a polysaccharide from Astragalus membranaceus
- (2009) Shi-gang Li et al. CARBOHYDRATE POLYMERS
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- (2009) Mingzhu Zhu et al. JOURNAL OF DRUG TARGETING
- Protection against cisplatin-induced nephrotoxicity in mice by Curcuma comosa Roxb. ethanol extract
- (2009) Surawat Jariyawat et al. Journal of Natural Medicines
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- (2009) Q.-L. Ma et al. JOURNAL OF NEUROSCIENCE
- Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-β in rats with unilateral ureteral obstruction
- (2009) Chuan Zuo et al. Journal of Zhejiang University-SCIENCE B
- Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications for cancer prevention
- (2009) Mohammad Iqbal et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Predicting new molecular targets for known drugs
- (2009) Michael J. Keiser et al. NATURE
- Mechanisms of drug combinations: interaction and network perspectives
- (2009) Jia Jia et al. NATURE REVIEWS DRUG DISCOVERY
- A simple isocratic HPLC method for the simultaneous determination of curcuminoids in commercial turmeric extracts
- (2009) Wisut Wichitnithad et al. PHYTOCHEMICAL ANALYSIS
- A Review of the Effects of Growth Hormone Changes on Symptoms of Frailty in the Elderly with Chronic Kidney Disease
- (2009) Emaad Abdel-Rahman et al. SEMINARS IN DIALYSIS
- 197: Role of Renin Angiotensin System (RAS) in Anemia Related to Chronic Kidney Disease (CKD)
- (2008) Aniruddha Palya et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Renal Parenchymal Hypoxia, Hypoxia Response and the Progression of Chronic Kidney Disease
- (2008) Samuel N. Heyman et al. AMERICAN JOURNAL OF NEPHROLOGY
- Identification of Information Flow-Modulating Drug Targets: A Novel Bridging Paradigm for Drug Discovery
- (2008) W-C Hwang et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
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- (2008) Zhenwei Gong et al. ENDOCRINOLOGY
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- (2008) V Eybl et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Application of high-performance liquid chromatography–electrospray ionization time-of-flight mass spectrometry for analysis and quality control of Radix Astragali and its preparations
- (2008) Lian-Wen Qi et al. JOURNAL OF CHROMATOGRAPHY A
- Advancement in analysis of Salviae miltiorrhizae Radix et Rhizoma (Danshen)
- (2008) Yong-Guo Li et al. JOURNAL OF CHROMATOGRAPHY A
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- (2008) Jianxiong Yang et al. JOURNAL OF ETHNOPHARMACOLOGY
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- Traditional Chinese medicine
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- (2008) R. Stone SCIENCE
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- (2008) Xiaohai Guan et al. TRANSPLANT INTERNATIONAL
- A systematic review of patient and health system characteristics associated with late referral in chronic kidney disease
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- (2007) S. Nagao et al. KIDNEY INTERNATIONAL
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