Adult ovarian granulosa cell tumor transcriptomics: prevalence of FOXL2 target genes misregulation gives insights into the pathogenic mechanism of the p.Cys134Trp somatic mutation
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Title
Adult ovarian granulosa cell tumor transcriptomics: prevalence of FOXL2 target genes misregulation gives insights into the pathogenic mechanism of the p.Cys134Trp somatic mutation
Authors
Keywords
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Journal
ONCOGENE
Volume 32, Issue 22, Pages 2739-2746
Publisher
Springer Nature
Online
2012-07-16
DOI
10.1038/onc.2012.298
References
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- Transcription factor FOXL2 protects granulosa cells from stress and delays cell cycle: role of its regulation by the SIRT1 deacetylase
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- Removing Batch Effects in Analysis of Expression Microarray Data: An Evaluation of Six Batch Adjustment Methods
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- GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis
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- Defective Gonadotropin-Dependent Ovarian Folliculogenesis and Granulosa Cell Gene Expression in Inhibin-Deficient Mice
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- Mutational analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers
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- Differential apoptotic activities of wild-type FOXL2 and the adult-type granulosa cell tumor-associated mutant FOXL2 (C134W)
- (2010) J-H Kim et al. ONCOGENE
- Functional Exploration of the Adult Ovarian Granulosa Cell Tumor-Associated Somatic FOXL2 Mutation p.Cys134Trp (c.402C>G)
- (2010) Bérénice A. Benayoun et al. PLoS One
- Aromatase Is a Direct Target of FOXL2: C134W in Granulosa Cell Tumors via a Single Highly Conserved Binding Site in the Ovarian Specific Promoter
- (2010) Nicholas I. Fleming et al. PLoS One
- GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
- (2009) Eran Eden et al. BMC BIOINFORMATICS
- Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation
- (2009) N. Henriette Uhlenhaut et al. CELL
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary
- (2009) Sohrab P. Shah et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Specificity of the FOXL2 c.402C>G Somatic Mutation: A Survey of Solid Tumors
- (2009) Kasmintan A. Schrader et al. PLoS One
- The new molecular biology of granulosa cell tumors of the ovary
- (2009) Nicolas Kalfa et al. Genome Medicine
- Positive and negative feedback regulates the transcription factor FOXL2 in response to cell stress: evidence for a regulatory imbalance induced by disease-causing mutations
- (2008) Bérénice A. Benayoun et al. HUMAN MOLECULAR GENETICS
- FoxL2 and Smad3 Coordinately Regulate Follistatin Gene Transcription
- (2008) Amy L. Blount et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Granulosa cell tumor of the ovary
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