Transcription factor FOXL2 protects granulosa cells from stress and delays cell cycle: role of its regulation by the SIRT1 deacetylase

GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis

(2010) Antti Kyrönlahti et al.   ENDOCRINE-RELATED CANCER

Mutational analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers

(2010) Min Sung Kim et al.   JOURNAL OF PATHOLOGY

The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary

(2010) Stacey Jamieson et al.   MODERN PATHOLOGY

SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2

(2010) Barrie Peck et al.   MOLECULAR CANCER THERAPEUTICS

FOXL2 Interacts with Steroidogenic Factor-1 (SF-1) and Represses SF-1-InducedCYP17Transcription in Granulosa Cells

(2010) Mira Park et al.   MOLECULAR ENDOCRINOLOGY

FoxL2 Is Required for Activin Induction of the Mouse and Human Follicle-Stimulating Hormone β-Subunit Genes

(2010) Patrick S. Corpuz et al.   MOLECULAR ENDOCRINOLOGY

Functional Exploration of the Adult Ovarian Granulosa Cell Tumor-Associated Somatic FOXL2 Mutation p.Cys134Trp (c.402C>G)

(2010) Bérénice A. Benayoun et al.   PLoS One

Microarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter

(2010) Jean M Escudero et al.   Journal of Ovarian Research

Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation

(2009) N. Henriette Uhlenhaut et al.   CELL

Human forkhead L2 represses key genes in granulosa cell differentiation including aromatase, P450scc, and cyclin D2

(2009) Ikuko K. Bentsi-Barnes et al.   FERTILITY AND STERILITY

Towards a functional classification of pathogenic FOXL2 mutations using transactivation reporter systems

(2009) Aurélie Dipietromaria et al.   HUMAN MOLECULAR GENETICS

Functional evidence implicating FOXL2 in non-syndromic premature ovarian failure and in the regulation of the transcription factor OSR2

(2009) P Laissue et al.   JOURNAL OF MEDICAL GENETICS

A Novel Role for the Forkhead Transcription Factor FOXL2 in Activin A-Regulated Follicle-Stimulating Hormone β Subunit Transcription

(2009) Pankaj Lamba et al.   MOLECULAR ENDOCRINOLOGY

The evolution of Fox genes and their role in development and disease

(2009) Sridhar Hannenhalli et al.   NATURE REVIEWS GENETICS

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

(2009) Sohrab P. Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Specificity of the FOXL2 c.402C>G Somatic Mutation: A Survey of Solid Tumors

(2009) Kasmintan A. Schrader et al.   PLoS One

Role of Sertoli cell number and function on regulation of spermatogenesis

(2008) Larry Johnson et al.   ANIMAL REPRODUCTION SCIENCE

Positive and negative feedback regulates the transcription factor FOXL2 in response to cell stress: evidence for a regulatory imbalance induced by disease-causing mutations

(2008) Bérénice A. Benayoun et al.   HUMAN MOLECULAR GENETICS

The identification and characterization of a FOXL2 response element provides insights into the pathogenesis of mutant alleles

(2008) Bérénice A. Benayoun et al.   HUMAN MOLECULAR GENETICS

Growth arrest and DNA damage-45 alpha (GADD45α)

(2008) A. Rosemary Siafakas et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

FoxL2 and Smad3 Coordinately Regulate Follistatin Gene Transcription

(2008) Amy L. Blount et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The post-translational modification profile of the forkhead transcription factor FOXL2 suggests the existence of parallel processive/concerted modification pathways

(2008) Bérénice A. Benayoun et al.   PROTEOMICS

Granulosa cell tumor of the ovary

(2007) D. Pectasides et al.   CANCER TREATMENT REVIEWS