Loss of aPKCλ in Differentiated Neurons Disrupts the Polarity Complex but Does Not Induce Obvious Neuronal Loss or Disorientation in Mouse Brains

PKCλ is critical in AMPA receptor phosphorylation and synaptic incorporation during LTP

(2013) Si-Qiang Ren et al.   EMBO JOURNAL

The Adhesion-GPCR BAI1 Regulates Synaptogenesis by Controlling the Recruitment of the Par3/Tiam1 Polarity Complex to Synaptic Sites

(2013) J. G. Duman et al.   JOURNAL OF NEUROSCIENCE

GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas

(2013) Scott X. Atwood et al.   NATURE

Prkcz null mice show normal learning and memory

(2013) Anna M. Lee et al.   NATURE

PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory

(2013) Lenora J. Volk et al.   NATURE

Phenotypical Analysis of Atypical PKCs In Vivo Function Display a Compensatory System at Mouse Embryonic Day 7.5

(2013) Sebastian Seidl et al.   PLoS One

Genetic dissection of medial habenula–interpeduncular nucleus pathway function in mice

(2013) Yuki Kobayashi et al.   Frontiers in Behavioral Neuroscience

Tumor Type-Dependent Function of the Par3 Polarity Protein in Skin Tumorigenesis

(2012) Sandra Iden et al.   CANCER CELL

Loss of the Par3 Polarity Protein Promotes Breast Tumorigenesis and Metastasis

(2012) Luke Martin McCaffrey et al.   CANCER CELL

Loss of Par3 promotes breast cancer metastasis by compromising cell–cell cohesion

(2012) Bin Xue et al.   NATURE CELL BIOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Lgl1 Activation of Rab10 Promotes Axonal Membrane Trafficking Underlying Neuronal Polarization

(2011) Tong Wang et al.   DEVELOPMENTAL CELL

Phosphorylation of E3 Ligase Smurf1 Switches Its Substrate Preference in Support of Axon Development

(2011) Pei-lin Cheng et al.   NEURON

Epithelial organization, cell polarity and tumorigenesis

(2011) Luke Martin McCaffrey et al.   TRENDS IN CELL BIOLOGY

TGF-β Signaling Specifies Axons during Brain Development

(2010) Jason J. Yi et al.   CELL

Par proteins and neuronal polarity

(2010) Ryan Insolera et al.   Developmental Neurobiology

Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction

(2010) T. Yamanaka et al.   HUMAN MOLECULAR GENETICS

Atypical Protein Kinase C Regulates Primary Dendrite Specification of Cerebellar Purkinje Cells by Localizing Golgi Apparatus

(2010) K. Tanabe et al.   JOURNAL OF NEUROSCIENCE

Atypical Protein Kinase C  Is Required for Bronchioalveolar Stem Cell Expansion and Lung Tumorigenesis

(2009) R. P. Regala et al.   CANCER RESEARCH

The apicobasal polarity kinase aPKC functions as a nuclear determinant and regulates cell proliferation and fate during Xenopus primary neurogenesis

(2009) N. Sabherwal et al.   DEVELOPMENT

A cell polarity protein aPKCλ is required for eye lens formation and growth

(2009) Yuki Sugiyama et al.   DEVELOPMENTAL BIOLOGY

PAR-1 Phosphorylates Mind Bomb to Promote Vertebrate Neurogenesis

(2009) Olga Ossipova et al.   DEVELOPMENTAL CELL

The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis

(2009) L. M. McCaffrey et al.   GENES & DEVELOPMENT

Axonal elongation triggered by stimulus-induced local translation of a polarity complex protein

(2009) Ulrich Hengst et al.   NATURE CELL BIOLOGY

An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics

(2009) Daisuke Mori et al.   NATURE CELL BIOLOGY

Spindle orientation during asymmetric cell division

(2009) Karsten H. Siller et al.   NATURE CELL BIOLOGY

Myosin II Motors and F-Actin Dynamics Drive the Coordinated Movement of the Centrosome and Soma during CNS Glial-Guided Neuronal Migration

(2009) David J. Solecki et al.   NEURON

Mammalian Par3 Regulates Progenitor Cell Asymmetric Division via Notch Signaling in the Developing Neocortex

(2009) Ronald S. Bultje et al.   NEURON

An Essential Role of the Universal Polarity Protein, aPKCλ, on the Maintenance of Podocyte Slit Diaphragms

(2009) Tomonori Hirose et al.   PLoS One

A role for the TGF -Par6 polarity pathway in breast cancer progression

(2009) A. M. Viloria-Petit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Asymmetric Stem Cell Division

(2008) Juergen A. Knoblich   CELL

The PAR-6 Polarity Protein Regulates Dendritic Spine Morphogenesis through p190 RhoGAP and the Rho GTPase

(2008) Huaye Zhang et al.   DEVELOPMENTAL CELL

Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor

(2008) Tomoyuki Yamanaka et al.   EMBO JOURNAL

Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth

(2008) Tomoyuki Yamanaka   Frontiers in Bioscience-Landmark

Phosphatidylinositol-3-Kinase-Atypical Protein Kinase C Signaling Is Required for Wnt Attraction and Anterior-Posterior Axon Guidance

(2008) A. M. Wolf et al.   JOURNAL OF NEUROSCIENCE