GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas

Initial Assessment of Tumor Regrowth After Vismodegib in Advanced Basal Cell Carcinoma

(2012) Anne Lynn S. Chang et al.   ARCHIVES OF DERMATOLOGY

Hedgehog pathway inhibition and the race against tumor evolution

(2012) Scott X. Atwood et al.   JOURNAL OF CELL BIOLOGY

Establishment of Murine Basal Cell Carcinoma Allografts: A Potential Model for Preclinical Drug Testing and for Molecular Analysis

(2011) Grace Ying Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Amplification of the Driving Oncogene, KRAS or BRAF, Underpins Acquired Resistance to MEK1/2 Inhibitors in Colorectal Cancer Cells

(2011) A. S. Little et al.   Science Signaling

Non-consensus GLI binding sites in Hedgehog target gene regulation

(2010) Martina Winklmayr et al.   BMC MOLECULAR BIOLOGY

Itraconazole, a Commonly Used Antifungal that Inhibits Hedgehog Pathway Activity and Cancer Growth

(2010) James Kim et al.   CANCER CELL

Small Molecule Inhibition of GDC-0449 Refractory Smoothened Mutants and Downstream Mechanisms of Drug Resistance

(2010) Gerrit J. P. Dijkgraaf et al.   CANCER RESEARCH

Cell Polarity in Eggs and Epithelia: Parallels and Diversity

(2010) Daniel St Johnston et al.   CELL

MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling

(2010) Marina Bershteyn et al.   DEVELOPMENTAL CELL

Hedgehog controls neural stem cells through p53-independent regulation of Nanog

(2010) Agnese Po et al.   EMBO JOURNAL

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector

(2010) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis

(2010) E. Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

(2010) S. Buonamici et al.   Science Translational Medicine

aPKC Phosphorylates Miranda to Polarize Fate Determinants during Neuroblast Asymmetric Cell Division

(2009) Scott X. Atwood et al.   CURRENT BIOLOGY

Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

(2009) R. L. Yauch et al.   SCIENCE

A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb

(2008) S. A. Vokes et al.   GENES & DEVELOPMENT