Exosomes: Implications in HIV-1 Pathogenesis

Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex

(2015) Marisa N. Madison et al.   VIROLOGY

Interaction of HIV-1 Nef Protein with the Host Protein Alix Promotes Lysosomal Targeting of CD4 Receptor

(2014) Nathaly A. Amorim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical role for bone marrow stromal antigen 2 in acute Chikungunya virus infection

(2014) W. D. Mahauad-Fernandez et al.   JOURNAL OF GENERAL VIROLOGY

Human pegivirus RNA is found in multiple blood mononuclear cells in vivo and serum-derived viral RNA-containing particles are infectious in vitro

(2014) E. T. Chivero et al.   JOURNAL OF GENERAL VIROLOGY

Association of Cytokines With Exosomes in the Plasma of HIV-1–Seropositive Individuals

(2014) Kateena Addae Konadu et al.   JOURNAL OF INFECTIOUS DISEASES

Exosomes from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells License Quiescent CD4+ T Lymphocytes To Replicate HIV-1 through a Nef- and ADAM17-Dependent Mechanism

(2014) C. Arenaccio et al.   JOURNAL OF VIROLOGY

CD47-dependent immunomodulatory and angiogenic activities of extracellular vesicles produced by T cells

(2014) Sukhbir Kaur et al.   MATRIX BIOLOGY

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

(2014) L. Vojtech et al.   NUCLEIC ACIDS RESEARCH

Novel HIV-1 MiRNAs Stimulate TNFα Release in Human Macrophages via TLR8 Signaling Pathway

(2014) Mark A. Bernard et al.   PLoS One

Nef Neutralizes the Ability of Exosomes from CD4+ T Cells to Act as Decoys during HIV-1 Infection

(2014) Julianne V. de Carvalho et al.   PLoS One

Quantitative and stoichiometric analysis of the microRNA content of exosomes

(2014) J. R. Chevillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1

(2014) Claudia Arenaccio et al.   Retrovirology

Human semen contains exosomes with potent anti-HIV-1 activity

(2014) Marisa N Madison et al.   Retrovirology

Exosomes from breast milk inhibit HIV-1 infection of dendritic cells and subsequent viral transfer to CD4+ T cells

(2013) Tanja I. Näslund et al.   AIDS

Methamphetamine Inhibits HIV-1 Replication in CD4+ T Cells by Modulating Anti–HIV-1 miRNA Expression

(2013) Chinmay K. Mantri et al.   AMERICAN JOURNAL OF PATHOLOGY

CD169 mediates the capture of exosomes in spleen and lymph node

(2013) S. C. Saunderson et al.   BLOOD

Exosomes Derived from HIV-1-infected Cells Contain Trans-activation Response Element RNA

(2013) Aarthi Narayanan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes

(2013) Daniel Perez-Hernandez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

(2013) Marina Colombo et al.   JOURNAL OF CELL SCIENCE

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

(2013) Jianhua Li et al.   NATURE IMMUNOLOGY

Exosome Secretion Is Enhanced by Invadopodia and Drives Invasive Behavior

(2013) Daisuke Hoshino et al.   Cell Reports

Interferon-Inducible Mechanism of Dendritic Cell-Mediated HIV-1 Dissemination Is Dependent on Siglec-1/CD169

(2013) Wendy Blay Puryear et al.   PLoS Pathogens

Sequences within RNA coding for HIV-1 Gag p17 are efficiently targeted to exosomes

(2012) Sandra Columba Cabezas et al.   CELLULAR MICROBIOLOGY

Klebsiella pneumoniae secretes outer membrane vesicles that induce the innate immune response

(2012) Je Chul Lee et al.   FEMS MICROBIOLOGY LETTERS

Trans-infection but Not Infection from within Endosomal Compartments after Cell-to-cell HIV-1 Transfer to CD4+T Cells

(2012) Marc Permanyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical and Biologic Characterization of Exosomes and Microvesicles as Facilitators of HIV-1 Infection in Macrophages

(2012) I. Kadiu et al.   JOURNAL OF IMMUNOLOGY

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

(2012) Esther N. M. Nolte-’t Hoen et al.   NUCLEIC ACIDS RESEARCH

Cocaine Enhances HIV-1 Replication in CD4+ T Cells by Down-Regulating MiR-125b

(2012) Chinmay K. Mantri et al.   PLoS One

Prostasomes are heterogeneous regarding size and appearance but affiliated to one DNA-containing exosome family

(2012) Göran K. Ronquist et al.   PROSTATE

Siglec-1 Is a Novel Dendritic Cell Receptor That Mediates HIV-1 Trans-Infection Through Recognition of Viral Membrane Gangliosides

(2012) Nuria Izquierdo-Useros et al.   PLOS BIOLOGY

The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

(2011) Guillaume van Niel et al.   DEVELOPMENTAL CELL

Ca2+ Signaling Tools Acquired from Prostasomes Are Required for Progesterone-Induced Sperm Motility

(2011) K.-H. Park et al.   Science Signaling

Prostasomes as Potential Modulators of Tyrosine Phosphorylation in Human Spermatozoa

(2011) Shaliha Bechoua et al.   Systems Biology in Reproductive Medicine

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Genetic Characterization of HIV Type 1 Nef-Induced Vesicle Secretion

(2010) Syed A. Ali et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV Type 1 Nef Is Released from Infected Cells in CD45+ Microvesicles and Is Present in the Plasma of HIV-Infected Individuals

(2010) A.D. Raymond et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

TLR2-Mediated Expansion of MDSCs Is Dependent on the Source of Tumor Exosomes

(2010) Xiaoyu Xiang et al.   AMERICAN JOURNAL OF PATHOLOGY

Characterization of Two Distinct Populations of Epididymosomes Collected in the Intraluminal Compartment of the Bovine Cauda Epididymis1

(2010) Gilles Frenette et al.   BIOLOGY OF REPRODUCTION

Human prostasomes express CD48 and interfere with NK cell function

(2010) R. Tarazona et al.   IMMUNOBIOLOGY

Prostasomes: inhibitors of capacitation and modulators of cellular signalling in human sperm

(2010) H. Pons-Rejraji et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Nanostructural and Transcriptomic Analyses of Human Saliva Derived Exosomes

(2010) Viswanathan Palanisamy et al.   PLoS One

Characterization of Yeast Extracellular Vesicles: Evidence for the Participation of Different Pathways of Cellular Traffic in Vesicle Biogenesis

(2010) Débora L. Oliveira et al.   PLoS One

Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples

(2010) Javier Conde-Vancells et al.   Proteomics Clinical Applications

Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F

(2010) Atanu K. Khatua et al.   VIROLOGY

The ESCRT pathway and HIV-1 budding: Figure 1

(2009) Yoshiko Usami et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Massive Secretion by T Cells Is Caused by HIV Nef in Infected Cells and by Nef Transfer to Bystander Cells

(2009) Claudia Muratori et al.   Cell Host & Microbe

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

(2009) Mehmet Kesimer et al.   FASEB JOURNAL

Galectin-3 is associated with prostasomes in human semen

(2009) Jennifer L. Jones et al.   GLYCOCONJUGATE JOURNAL

Human Immunodeficiency Virus Type 1 Nef Protein Targets CD4 to the Multivesicular Body Pathway

(2009) L. L. P. daSilva et al.   JOURNAL OF VIROLOGY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

A role for CD81 on the late steps of HIV-1 replication in a chronically infected T cell line

(2009) Boyan Grigorov et al.   Retrovirology

HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

(2009) Metka Lenassi et al.   TRAFFIC

Multivesicular Endosome Biogenesis in the Absence of ESCRTs

(2009) Susanne Stuffers et al.   TRAFFIC

miR-198 Inhibits HIV-1 Gene Expression and Replication in Monocytes and Its Mechanism of Action Appears To Involve Repression of Cyclin T1

(2009) Tzu-Ling Sung et al.   PLoS Pathogens

Cellular microRNA expression correlates with susceptibility of monocytes/macrophages to HIV-1 infection

(2008) X. Wang et al.   BLOOD

Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

(2008) N. Izquierdo-Useros et al.   BLOOD

Discrimination between exosomes and HIV-1: Purification of both vesicles from cell-free supernatants

(2008) Réjean Cantin et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Exosomes Packaging APOBEC3G Confer Human Immunodeficiency Virus Resistance to Recipient Cells

(2008) A. K. Khatua et al.   JOURNAL OF VIROLOGY

Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication

(2008) Jasmine K Ahluwalia et al.   Retrovirology

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

HIV-1 Nef Targets MHC-I and CD4 for Degradation Via a Final Common β-COP–Dependent Pathway in T Cells

(2008) Malinda R. Schaefer et al.   PLoS Pathogens