Interaction of HIV-1 Nef Protein with the Host Protein Alix Promotes Lysosomal Targeting of CD4 Receptor

How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4

(2014) Xuefeng Ren et al.   eLife

The Yeast Alix Homolog Bro1 Functions as a Ubiquitin Receptor for Protein Sorting into Multivesicular Endosomes

(2013) Natasha Pashkova et al.   DEVELOPMENTAL CELL

Viral Infection Controlled by a Calcium-Dependent Lipid-Binding Module in ALIX

(2013) Christin Bissig et al.   DEVELOPMENTAL CELL

ALIX and the multivesicular endosome: ALIX in Wonderland

(2013) Christin Bissig et al.   TRENDS IN CELL BIOLOGY

ALIX binds a YPX3L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting

(2012) Michael R. Dores et al.   JOURNAL OF CELL BIOLOGY

AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway

(2012) Michael R. Dores et al.   MOLECULAR BIOLOGY OF THE CELL

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

One Protein to Rule them All: Modulation of Cell Surface Receptors and Molecules by HIV Nef

(2011) Alessia Landi et al.   CURRENT HIV RESEARCH

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

HIV-1 Nef Disrupts Intracellular Trafficking of Major Histocompatibility Complex Class I, CD4, CD8, and CD28 by Distinct Pathways That Share Common Elements

(2011) J. A. Leonard et al.   JOURNAL OF VIROLOGY

Immune Evasion and Counteraction of Restriction Factors by HIV-1 and Other Primate Lentiviruses

(2010) Frank Kirchhoff   Cell Host & Microbe

Alix regulates egress of hepatitis B virus naked capsid particles in an ESCRT-independent manner

(2010) Andreas Bardens et al.   CELLULAR MICROBIOLOGY

The Role of Ubiquitination in Lysosomal Trafficking of δ-Opioid Receptors

(2010) Anastasia G. Henry et al.   TRAFFIC

HIV-1 Nef Dimerization Is Required for Nef-Mediated Receptor Downregulation and Viral Replication

(2009) Jerrod A. Poe et al.   JOURNAL OF MOLECULAR BIOLOGY

A Basic Patch on  -Adaptin Is Required for Binding of Human Immunodeficiency Virus Type 1 Nef and Cooperative Assembly of a CD4-Nef-AP-2 Complex

(2009) R. Chaudhuri et al.   JOURNAL OF VIROLOGY

Human Immunodeficiency Virus Type 1 Nef Protein Targets CD4 to the Multivesicular Body Pathway

(2009) L. L. P. daSilva et al.   JOURNAL OF VIROLOGY

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

(2009) Camilla Raiborg et al.   NATURE

A Crescent-Shaped ALIX Dimer Targets ESCRT-III CHMP4 Filaments

(2009) Ricardo Pires et al.   STRUCTURE

Interactions between SIVNef, SIVGagPol and Alix correlate with viral replication and progression to AIDS in rhesus macaques

(2009) Luciana Jesus da Costa et al.   VIROLOGY

Bimolecular Fluorescence Complementation (BiFC) Analysis as a Probe of Protein Interactions in Living Cells

(2008) Tom K. Kerppola   Annual Review of Biophysics

HIV-1 Accessory Proteins—Ensuring Viral Survival in a Hostile Environment

(2008) Michael H. Malim et al.   Cell Host & Microbe

Retromer

(2008) Juan S Bonifacino et al.   CURRENT OPINION IN CELL BIOLOGY

Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor  -chain

(2008) Y. Yamashita et al.   JOURNAL OF CELL SCIENCE

In Vitro Budding of Intralumenal Vesicles into Late Endosomes Is Regulated by Alix and Tsg101

(2008) Thomas Falguières et al.   MOLECULAR BIOLOGY OF THE CELL

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

(2008) Bernard T. Kelly et al.   NATURE

ALIX-CHMP4 interactions in the human ESCRT pathway

(2008) J. McCullough et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Nef: at the crossroads

(2008) John L Foster et al.   Retrovirology

HIV-1 Nef Targets MHC-I and CD4 for Degradation Via a Final Common β-COP–Dependent Pathway in T Cells

(2008) Malinda R. Schaefer et al.   PLoS Pathogens