Intrinsically Disordered and Aggregation Prone Regions Underlie β-Aggregation in S100 Proteins

Intrinsic Disorder-based Protein Interactions and their Modulators

(2013) Vladimir N. Uversky   CURRENT PHARMACEUTICAL DESIGN

Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens

(2013) S. M. Damo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A decade and a half of protein intrinsic disorder: Biology still waits for physics

(2013) Vladimir N. Uversky   PROTEIN SCIENCE

Evolutionary selection for protein aggregation

(2012) Natalia Sanchez de Groot et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Protein Misfolded Oligomers: Experimental Approaches, Mechanism of Formation, and Structure-Toxicity Relationships

(2012) Francesco Bemporad et al.   CHEMISTRY & BIOLOGY

Metal ions as modulators of protein conformation and misfolding in neurodegeneration

(2012) Sónia S. Leal et al.   COORDINATION CHEMISTRY REVIEWS

Pro-Inflammatory S100A8 and S100A9 Proteins: Self-Assembly into Multifunctional Native and Amyloid Complexes

(2012) Thomas Vogl et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tyrosine Residues Mediate Fibril Formation in a Dynamic Light Chain Dimer Interface

(2012) Ara Celi DiCostanzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S100A6 Amyloid Fibril Formation Is Calcium-modulated and Enhances Superoxide Dismutase-1 (SOD1) Aggregation

(2012) Hugo M. Botelho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation

(2012) Samuel I.A. Cohen et al.   JOURNAL OF MOLECULAR BIOLOGY

The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory-Agency-Approved Drug

(2012) Steven M. Johnson et al.   JOURNAL OF MOLECULAR BIOLOGY

Targeting of Monomer/Misfolded SOD1 as a Therapeutic Strategy for Amyotrophic Lateral Sclerosis

(2012) H.-N. Liu et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein misfolding and Parkinson's disease

(2011) Leonid Breydo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Intrinsically disordered proteins may escape unwanted interactions via functional misfolding

(2011) Vladimir N. Uversky   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Multiphoton ANS fluorescence microscopy as an in vivo sensor for protein misfolding stress

(2011) Kevin C. Hadley et al.   CELL STRESS & CHAPERONES

Mapping out the multistage fibrillation of glucagon

(2011) Shirin Ghodke et al.   FEBS Journal

Intrinsic disorder in S100 proteins

(2011) Sergei E. Permyakov et al.   Molecular BioSystems

Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states

(2010) Mikael Lindgren et al.   FEBS Journal

Natural and amyloid self-assembly of S100 proteins: structural basis of functional diversity

(2010) Günter Fritz et al.   FEBS Journal

Substoichiometric Levels of Cu2+Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer Disease

(2010) Claire J. Sarell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

(2010) Sebastian Maurer-Stroh et al.   NATURE METHODS

S100A4 and Metastasis

(2009) Kjetil Boye et al.   AMERICAN JOURNAL OF PATHOLOGY

Formation of Monomeric S100B and S100A11 Proteins at Low Ionic Strength†

(2009) Nicole M. Marlatt et al.   BIOCHEMISTRY

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function

(2009) Olga V Moroz et al.   BMC BIOCHEMISTRY

The Crystal Structures of Human S100A12 in Apo Form and in Complex with Zinc: New Insights into S100A12 Oligomerisation

(2009) Olga V. Moroz et al.   JOURNAL OF MOLECULAR BIOLOGY

Amyloid Formation by the Pro-Inflammatory S100A8/A9 Proteins in the Ageing Prostate

(2009) Kiran Yanamandra et al.   PLoS One

The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis

(2008) Thamir M. Ismail et al.   CARCINOGENESIS

The Zyggregator method for predicting protein aggregation propensities

(2008) Gian Gaetano Tartaglia et al.   CHEMICAL SOCIETY REVIEWS

Crystal Structure of Ca2+-Free S100A2 at 1.6-Å Resolution

(2008) Michael Koch et al.   JOURNAL OF MOLECULAR BIOLOGY

Prediction of Aggregation-Prone Regions in Structured Proteins

(2008) Gian Gaetano Tartaglia et al.   JOURNAL OF MOLECULAR BIOLOGY

Analysis of the structure of human apo-S100B at low temperature indicates a unimodal conformational distribution is adopted by calcium-free S100 proteins

(2008) Shahid Malik et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A review of the S100 proteins in cancer

(2007) I. Salama et al.   EJSO