Prognostic Importance and Therapeutic Implications of PAK1, a Drugable Protein Kinase, in Gastroesophageal Junction Adenocarcinoma

The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes

(2015) Ruchi Singhal et al.   Oncotarget

Esophagus or Stomach? The Seventh TNM Classification for Siewert Type II/III Junctional Adenocarcinoma

(2012) Shinichi Hasegawa et al.   ANNALS OF SURGICAL ONCOLOGY

p21-activated kinases and gastrointestinal cancer

(2012) Hong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular Pathways: Targeting P21-Activated Kinase 1 Signaling in Cancer--Opportunities, Challenges, and Limitations

(2012) J. Eswaran et al.   CLINICAL CANCER RESEARCH

Thrombin stimulation of inflammatory breast cancer cells leads to aggressiveness via the EGFR-PAR1-Pak1 pathway

(2012) Kazufumi Ohshiro et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS

Genome-Wide Screening for Genetic Alterations in Esophageal Cancer by aCGH Identifies 11q13 Amplification Oncogenes Associated with Nodal Metastasis

(2012) Jianming Ying et al.   PLoS One

Overcoming resistance to tyrosine kinase inhibitors: Lessons learned from cancer cells treated with EGFR antagonists

(2011) Brent N. Rexer et al.   CELL CYCLE

Differences underlying EGFR and HER2 oncogene addiction

(2011) Anthony C. Faber et al.   CELL CYCLE

Potential role of minichromosome maintenance protein 2 as a screening biomarker in esophageal cancer high-risk population in China

(2011) Bo Huang et al.   HUMAN PATHOLOGY

PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

(2011) Y Shrestha et al.   ONCOGENE

Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells

(2011) C. C. Ong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular targeted agents for gastric and gastroesophageal junction cancer

(2011) Takashi Oshima et al.   SURGERY TODAY

HER2 Testing in Gastric and Gastroesophageal Junction Cancers

(2011) David G. Hicks et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Curcumin suppresses proliferation and invasion in human gastric cancer cells by down-regulation of PAK1 activity and cyclin D1 expression

(2010) Xin-Ze Cai et al.   CANCER BIOLOGY & THERAPY

Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array–comparative genomic hybridization

(2010) Anna Isinger-Ekstrand et al.   CANCER GENETICS AND CYTOGENETICS

Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer

(2010) Motohisa Tada et al.   CANCER SCIENCE

Estrogen Receptor-  Phosphorylation at Serine 305, Nuclear p21-Activated Kinase 1 Expression, and Response to Tamoxifen in Postmenopausal Breast Cancer

(2010) J. Bostner et al.   CLINICAL CANCER RESEARCH

Esophageal Adenocarcinoma: Treatment Modalities in the Era of Targeted Therapy

(2010) Kaushik Mukherjee et al.   DIGESTIVE DISEASES AND SCIENCES

PAK1 as a therapeutic target

(2010) Julia V Kichina et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Predictive Value of Initial PET-SUVmax in Patients with Locally Advanced Esophageal and Gastroesophageal Junction Adenocarcinoma

(2010) Nabil P. Rizk et al.   Journal of Thoracic Oncology

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

(2010) Yung-Jue Bang et al.   LANCET

Gastric cardiac carcinomas involving the esophagus are more adequately staged as gastric cancers by the 7th edition of the American Joint Commission on Cancer Staging System

(2010) Qin Huang et al.   MODERN PATHOLOGY

A Rac–Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells

(2010) L E Arias-Romero et al.   ONCOGENE

Predicting Response to Treatment in Gastroesophageal Junction Adenocarcinomas: Combining Clinical, Imaging, and Molecular Biomarkers

(2010) G. H. Bain et al.   ONCOLOGIST

Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1

(2009) Funan Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Does Neoadjuvant Treatment for Gastric Cancer Patients with Positive Peritoneal Cytology at Staging Laparoscopy Improve Survival?

(2008) Brian Badgwell et al.   ANNALS OF SURGICAL ONCOLOGY

Analysis of Basement Membrane Structure and Inflammation During the Development of Esophageal Squamous Cell Carcinoma in the Chinese Chaoshan High Risk Region

(2008) Guo-Hong Zhang et al.   CANCER INVESTIGATION

ErbB receptors in the biology and pathology of the aerodigestive tract

(2008) Sarah Morgan et al.   EXPERIMENTAL CELL RESEARCH

Changing trends in the proportion of adenocarcinoma of the esophagogastric junction in a large tertiary referral center in Japan

(2008) Chika Kusano et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Multidisciplinary management of gastric and gastroesophageal cancers

(2008) Markus Moehler et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Esophageal and Gastric Cardia Cancers on 4238 Chinese Patients Residing in Municipal and Rural Regions: A Histopathological Comparison During 24-Year Period

(2008) Yu Jing Fan et al.   WORLD JOURNAL OF SURGERY