Role for Krüppel-Like Transcription Factor 11 in Mesenchymal Cell Function and Fibrosis

A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment

(2013) Minoti V. Apte et al.   GASTROENTEROLOGY

Hepatic stellate cells in liver development, regeneration, and cancer

(2013) Chunyue Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetics: A Promising Paradigm for Better Understanding and Managing Pain

(2013) Seungmae Seo et al.   JOURNAL OF PAIN

Pancreatic Stellate Cell Models for Transcriptional Studies of Desmoplasia-Associated Genes

(2013) Angela Mathison et al.   PANCREATOLOGY

Krüppel-like Factor 11 Differentially Couples to Histone Acetyltransferase and Histone Methyltransferase Chromatin Remodeling Pathways to Transcriptionally Regulate Dopamine D2 Receptor in Neuronal Cells

(2012) Seungmae Seo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic Role for a Novel Glucocorticoid-KLF11 (TIEG2) Protein Pathway in Stress-induced Monoamine Oxidase A Expression

(2012) Matthew Grunewald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequence-specific Recruitment of Heterochromatin Protein 1 via Interaction with Krüppel-like Factor 11, a Human Transcription Factor Involved in Tumor Suppression and Metabolic Diseases

(2012) Gwen Lomberk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse KLF11 regulates hepatic lipid metabolism

(2012) Huabing Zhang et al.   JOURNAL OF HEPATOLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

The role of stroma in pancreatic cancer: diagnostic and therapeutic implications

(2012) Mert Erkan et al.   Nature Reviews Gastroenterology & Hepatology

The extracellular matrix: an active or passive player in fibrosis?

(2011) Thomas N. Wight et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Disruption of a Novel Krüppel-like Transcription Factor p300-regulated Pathway for Insulin Biosynthesis Revealed by Studies of the c.-331INSMutation Found in Neonatal Diabetes Mellitus

(2011) Amélie Bonnefond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ephrin B2/EphB4 pathway in hepatic stellate cells stimulates Erk-dependent VEGF production and sinusoidal endothelial cell recruitment

(2010) Amitava Das et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Distinct Role of Kruppel-like Factor 11 in the Regulation of Prostaglandin E2Biosynthesis

(2010) Navtej S. Buttar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma

(2009) Thomas Amann et al.   CANCER SCIENCE

Hepatic fibrosis

(2009) Jingjing Jiao et al.   CURRENT OPINION IN GASTROENTEROLOGY

MODY7Gene,KLF11, Is a Novel p300-dependent Regulator ofPdx-1(MODY4) Transcription in Pancreatic Islet β Cells

(2009) Martin E. Fernandez-Zapico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of steroid receptor co-activator-3 attenuates carbon tetrachloride-induced murine hepatic injury and fibrosis

(2009) Xinran Ma et al.   LABORATORY INVESTIGATION

KLF Family Members Regulate Intrinsic Axon Regeneration Ability

(2009) D. L. Moore et al.   SCIENCE

Inhibition of transforming growth factor-β-induced liver fibrosis by a retinoic acid derivative via the suppression of Col 1A2 promoter activity

(2008) Kun-Lin Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TGF-β regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3–Sp1–KLF6 interaction

(2008) Luisa M. Botella et al.   BIOCHEMICAL JOURNAL

The sunset of somatic genetics and the dawn of epigenetics: a new frontier in pancreatic cancer research

(2008) Gwen Lomberk et al.   CURRENT OPINION IN GASTROENTEROLOGY

The Kruppel-Like Factor 6 Genotype Is Associated With Fibrosis in Nonalcoholic Fatty Liver Disease

(2008) Luca Miele et al.   GASTROENTEROLOGY

Newly proposed fibrosis staging criterion for assessing carbon tetrachloride- and albumin complex-induced liver fibrosis in rodents

(2008) Xin-Yan Zhao et al.   PATHOLOGY INTERNATIONAL