Phage P1-Derived Artificial Chromosomes Facilitate Heterologous Expression of the FK506 Gene Cluster
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Title
Phage P1-Derived Artificial Chromosomes Facilitate Heterologous Expression of the FK506 Gene Cluster
Authors
Keywords
Streptomyces, Biosynthesis, Bacteriophages, Gene regulation, Genetic engineering, Mycelium, Cloning, Polymerase chain reaction
Journal
PLoS One
Volume 8, Issue 7, Pages e69319
Publisher
Public Library of Science (PLoS)
Online
2013-07-12
DOI
10.1371/journal.pone.0069319
References
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- (2013) Mamoru Komatsu et al. ACS Synthetic Biology
- Roles offkbNin Positive Regulation andtcs7in Negative Regulation of FK506 Biosynthesis in Streptomyces sp. Strain KCTC 11604BP
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- (2012) Dandan Chen et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Taxonomy and chemically semi-defined media for the analysis of the tacrolimus producer ‘Streptomyces tsukubaensis’
- (2012) Miriam Martínez-Castro et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis
- (2012) Dušan Goranovič et al. BMC MICROBIOLOGY
- Enhancement of tacrolimus productivity in Streptomyces tsukubaensis by the use of novel precursors for biosynthesis
- (2012) Jadwiga Turło et al. ENZYME AND MICROBIAL TECHNOLOGY
- Draft Genome of Streptomyces tsukubaensis NRRL 18488, the Producer of the Clinically Important Immunosuppressant Tacrolimus (FK506)
- (2012) C. Barreiro et al. JOURNAL OF BACTERIOLOGY
- Heterologous Production of 4-O-Demethylbarbamide, a Marine Cyanobacterial Natural Product
- (2012) Eun Ji Kim et al. ORGANIC LETTERS
- Novel chemobiosynthetic approach for exclusive production of FK506
- (2011) Gregor Kosec et al. METABOLIC ENGINEERING
- antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
- (2011) Marnix H. Medema et al. NUCLEIC ACIDS RESEARCH
- Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate
- (2011) J. N. Andexer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
- (2011) L. Laureti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cloning large natural product gene clusters from the environment: Piecing environmental DNA gene clusters back together with TAR
- (2010) Jeffrey H. Kim et al. BIOPOLYMERS
- Heterologous expression of the biosynthetic gene clusters of coumermycin A1, clorobiocin and caprazamycins in genetically modified Streptomyces coelicolor strains
- (2010) Katrin Flinspach et al. BIOPOLYMERS
- Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules
- (2010) Jacob J Banik et al. CURRENT OPINION IN MICROBIOLOGY
- Origin of the Allyl Group in FK506 Biosynthesis
- (2010) Dušan Goranovič et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biosynthesis of the Allylmalonyl-CoA Extender Unit for the FK506 Polyketide Synthase Proceeds through a Dedicated Polyketide Synthase and Facilitates the Mutasynthesis of Analogues
- (2010) SangJoon Mo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters
- (2010) Juan Pablo Gomez-Escribano et al. Microbial Biotechnology
- Cloning and Sequencing of the Biosynthetic Gene Cluster for Saquayamycin Z and Galtamycin B and the Elucidation of the Assembly of Their Saccharide Chains
- (2009) Annette Erb et al. CHEMBIOCHEM
- Long-term safety of tacrolimus ointment in atopic dermatitis
- (2009) Anita Remitz et al. Expert Opinion On Drug Safety
- Reducing the variability of antibiotic production in Streptomyces by cultivation in 24-square deepwell plates
- (2009) Stefanie Siebenberg et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- Enhanced FK506 production in Streptomyces clavuligerus CKD1119 by engineering the supply of methylmalonyl-CoA precursor
- (2009) SangJoon Mo et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Transcriptional regulation of the novobiocin biosynthetic gene cluster
- (2009) V. Dangel et al. MICROBIOLOGY-SGM
- Genomic basis for natural product biosynthetic diversity in the actinomycetes
- (2009) Markus Nett et al. NATURAL PRODUCT REPORTS
- Renaissance in antibacterial discovery from actinomycetes
- (2008) R BALTZ CURRENT OPINION IN PHARMACOLOGY
- Selective isolation of genomic loci from complex genomes by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae
- (2008) Natalay Kouprina et al. Nature Protocols
- Heterologous Expression And Genetic Engineering of the Phenalinolactone Biosynthetic Gene Cluster by Using Red/ET Recombineering
- (2007) Tina M. Binz et al. CHEMBIOCHEM
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