FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis

Roles offkbNin Positive Regulation andtcs7in Negative Regulation of FK506 Biosynthesis in Streptomyces sp. Strain KCTC 11604BP

(2012) SangJoon Mo et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Improvement of FK506 Production in Streptomyces tsukubaensis by Genetic Enhancement of the Supply of Unusual Polyketide Extender Units via Utilization of Two Distinct Site-Specific Recombination Systems

(2012) Dandan Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Characterisation of a γ-butyrolactone receptor of Streptomyces tacrolimicus: effect on sporulation and tacrolimus biosynthesis

(2011) Zahra Salehi-Najafabadi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Novel chemobiosynthetic approach for exclusive production of FK506

(2011) Gregor Kosec et al.   METABOLIC ENGINEERING

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

(2010) Juan-Francisco Martín et al.   CURRENT OPINION IN MICROBIOLOGY

Origin of the Allyl Group in FK506 Biosynthesis

(2010) Dušan Goranovič et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Robust reporter system based on chalcone synthase rppA gene from Saccharopolyspora erythraea

(2010) V. Magdevska et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Biosynthesis of the Allylmalonyl-CoA Extender Unit for the FK506 Polyketide Synthase Proceeds through a Dedicated Polyketide Synthase and Facilitates the Mutasynthesis of Analogues

(2010) SangJoon Mo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

(2010) Y. Zhuo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs

(2009) Edmund I. Graziani   NATURAL PRODUCT REPORTS

The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997

(2008) Weiqing He et al.   ARCHIVES OF MICROBIOLOGY

The use of the rare UUA codon to define “Expression Space” for genes involved in secondary metabolism, development and environmental adaptation in Streptomyces

(2008) Keith F. Chater et al.   JOURNAL OF MICROBIOLOGY