Improvement of Neuromuscular Synaptic Phenotypes without Enhanced Survival and Motor Function in Severe Spinal Muscular Atrophy Mice Selectively Rescued in Motor Neurons
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Title
Improvement of Neuromuscular Synaptic Phenotypes without Enhanced Survival and Motor Function in Severe Spinal Muscular Atrophy Mice Selectively Rescued in Motor Neurons
Authors
Keywords
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Journal
PLoS One
Volume 8, Issue 9, Pages e75866
Publisher
Public Library of Science (PLoS)
Online
2013-09-24
DOI
10.1371/journal.pone.0075866
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- (2012) R. G. Gogliotti et al. JOURNAL OF NEUROSCIENCE
- Survival Motor Neuron Protein in Motor Neurons Determines Synaptic Integrity in Spinal Muscular Atrophy
- (2012) T. L. Martinez et al. JOURNAL OF NEUROSCIENCE
- Limited Phenotypic Effects of Selectively Augmenting the SMN Protein in the Neurons of a Mouse Model of Severe Spinal Muscular Atrophy
- (2012) Andrew J-H. Lee et al. PLoS One
- Spinal muscular atrophy: going beyond the motor neuron
- (2012) Gillian Hamilton et al. TRENDS IN MOLECULAR MEDICINE
- Spinal Muscular Atrophy
- (2011) Stephen J. Kolb ARCHIVES OF NEUROLOGY
- Muscles in a mouse model of spinal muscular atrophy show profound defects in neuromuscular development even in the absence of failure in neuromuscular transmission or loss of motor neurons
- (2011) Young il Lee et al. DEVELOPMENTAL BIOLOGY
- A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse
- (2011) Paul N. Porensky et al. HUMAN MOLECULAR GENETICS
- Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy
- (2011) K. K. Y. Ling et al. HUMAN MOLECULAR GENETICS
- Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy
- (2011) Cathleen M. Lutz et al. JOURNAL OF CLINICAL INVESTIGATION
- Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
- (2011) Yimin Hua et al. NATURE
- A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology
- (2011) Mélissa Bowerman et al. NEUROMUSCULAR DISORDERS
- SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals
- (2011) Laura Torres-Benito et al. PLoS One
- CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy
- (2010) Marco A. Passini et al. JOURNAL OF CLINICAL INVESTIGATION
- Reduced Survival of Motor Neuron (SMN) Protein in Motor Neuronal Progenitors Functions Cell Autonomously to Cause Spinal Muscular Atrophy in Model Mice Expressing the Human Centromeric (SMN2) Gene
- (2010) G.-H. Park et al. JOURNAL OF NEUROSCIENCE
- Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN
- (2010) Kevin D Foust et al. NATURE BIOTECHNOLOGY
- Mouse Survival Motor Neuron Alleles That Mimic SMN2 Splicing and Are Inducible Rescue Embryonic Lethality Early in Development but Not Late
- (2010) Suzan M. Hammond et al. PLoS One
- Impaired Synaptic Vesicle Release and Immaturity of Neuromuscular Junctions in Spinal Muscular Atrophy Mice
- (2009) L. Kong et al. JOURNAL OF NEUROSCIENCE
- Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
- (2009) Arthur H. M. Burghes et al. NATURE REVIEWS NEUROSCIENCE
- A Cluster of Cholinergic Premotor Interneurons Modulates Mouse Locomotor Activity
- (2009) Laskaro Zagoraiou et al. NEURON
- Identification of a battery of tests for drug candidate evaluation in the SMNΔ7 neonate model of spinal muscular atrophy
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- Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect
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