Indoxyl Sulfate Down-Regulates SLCO4C1 Transporter through Up-Regulation of GATA3

Current Understanding of Drug Disposition in Kidney Disease

(2012) Judith Naud et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Normal and Pathologic Concentrations of Uremic Toxins

(2012) F. Duranton et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Antioxidant EPC-K1 Attenuates Renal Ischemia-Reperfusion Injury in a Rat Model

(2011) Shunsuke Yamamoto et al.   AMERICAN JOURNAL OF NEPHROLOGY

NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells

(2011) Hidehisa Shimizu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effects of Chronic Renal Failure on Kidney Drug Transporters and Cytochrome P450 in Rats

(2011) J. Naud et al.   DRUG METABOLISM AND DISPOSITION

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice

(2011) Mei Tran et al.   JOURNAL OF CLINICAL INVESTIGATION

Update on the Pharmacokinetics and Redox Properties of Protein-Bound Uremic Toxins

(2011) Hiroshi Watanabe et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Transcriptional Regulation of Organic Anion Transporting Polypeptide SLCO4C1 as a New Therapeutic Modality to Prevent Chronic Kidney Disease

(2011) Takehiro Suzuki et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

An Update on Protein-Bound Uremic Retention Solutes

(2011) Raymond Vanholder et al.   JOURNAL OF RENAL NUTRITION

Uremic Toxins Inhibit Transport by Breast Cancer Resistance Protein and Multidrug Resistance Protein 4 at Clinically Relevant Concentrations

(2011) Henricus A. M. Mutsaers et al.   PLoS One

Role of Indoxyl Sulfate in the Progression of Chronic Kidney Disease and Cardiovascular Disease: Experimental and Clinical Effects of Oral Sorbent AST-120

(2011) Toshimitsu Niwa   THERAPEUTIC APHERESIS AND DIALYSIS

Inflammation-mediated changes in drug transporter expression/activity: implications for therapeutic drug response

(2011) Alexander M Cressman et al.   Expert Review of Clinical Pharmacology

Indoxyl Sulfate Upregulates Expression of ICAM-1 and MCP-1 by Oxidative Stress-Induced NF-ĸB Activation

(2010) Zohra Tumur et al.   AMERICAN JOURNAL OF NEPHROLOGY

Simultaneous determination of guanidinosuccinic acid and guanidinoacetic acid in urine using high performance liquid chromatography/tandem mass spectrometry

(2010) Daisuke Saigusa et al.   ANALYTICA CHIMICA ACTA

Guanidino Compounds as Cause of Cardiovascular Damage in Chronic Kidney Disease: An in vitro Evaluation

(2010) Eva Schepers et al.   BLOOD PURIFICATION

Indoxyl Sulfate-Induced Endothelial Dysfunction in Patients with Chronic Kidney Disease via an Induction of Oxidative Stress

(2010) M. Yu et al.   Clinical Journal of the American Society of Nephrology

Regulation of Drug Metabolism and Transporters

(2010) Jordi Muntane   CURRENT DRUG METABOLISM

Metabolomic profiling of uremic solutes in CKD patients

(2010) Takafumi Toyohara et al.   HYPERTENSION RESEARCH

SLCO4C1 Transporter Eliminates Uremic Toxins and Attenuates Hypertension and Renal Inflammation

(2009) T. Toyohara et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Guanidino Compounds as Uremic (Neuro)Toxins

(2009) Peter Paul De Deyn et al.   SEMINARS IN DIALYSIS

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression

(2008) N. Obara et al.   BLOOD

Emerging Evidence of the Impact of Kidney Disease on Drug Metabolism and Transport

(2008) TD Nolin et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

New insights into uremic toxicity

(2008) Amanda C Raff et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

A Bench to Bedside View of Uremic Toxins

(2008) R. Vanholder et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY