Zinc Finger Nuclease Mediated Knockout of ADP-Dependent Glucokinase in Cancer Cell Lines: Effects on Cell Survival and Mitochondrial Oxidative Metabolism

Identification of functional elements of the GDP-fucose transporter SLC35C1 using a novel Chinese hamster ovary mutant

(2012) Peiqing Zhang et al.   GLYCOBIOLOGY

Expression and role in glycolysis of human ADP-dependent glucokinase

(2012) Susan Richter et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

T cell Activation Is Driven by an ADP-Dependent Glucokinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation

(2012) Marcin M. Kamiński et al.   Cell Reports

GeneSetDB: A comprehensive meta-database, statistical and visualisation framework for gene set analysis

(2012) Hiromitsu Araki et al.   FEBS Open Bio

Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration

(2011) Ryan J. Mailloux et al.   BIOCHEMICAL JOURNAL

Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells

(2011) Lianchun Fan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Zinc-Finger Nucleases: A Panoramic View

(2011) Dana Carroll   CURRENT GENE THERAPY

An unbiased genome-wide analysis of zinc-finger nuclease specificity

(2011) Richard Gabriel et al.   NATURE BIOTECHNOLOGY

Mining the O-glycoproteome using zinc-finger nuclease–glycoengineered SimpleCell lines

(2011) Catharina Steentoft et al.   NATURE METHODS

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

(2011) Vikram Pattanayak et al.   NATURE METHODS

Zinc-finger nucleases: how to play two good hands

(2011) Mark Isalan   NATURE METHODS

Enhancement of DNA uptake in FUT8-deleted CHO cells for transient production of afucosylated antibodies

(2010) Athena W. Wong et al.   BIOTECHNOLOGY AND BIOENGINEERING

L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells

(2010) K. Doberstein et al.   CARCINOGENESIS

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

(2010) Beate Neumann et al.   NATURE

Genome editing with engineered zinc finger nucleases

(2010) Fyodor D. Urnov et al.   NATURE REVIEWS GENETICS

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

BAKandBAXdeletion using zinc-finger nucleases yields apoptosis-resistant CHO cells

(2009) Gregory J. Cost et al.   BIOTECHNOLOGY AND BIOENGINEERING

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

(2009) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

N-cadherin knock-down decreases invasiveness of esophageal squamous cell carcinoma in vitro

(2009) Ke Li et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)

(2008) Masato Yoneda et al.   BMC GASTROENTEROLOGY

Comparison of Zinc Finger Nucleases for Use in Gene Targeting in Mammalian Cells

(2008) Shondra M Pruett-Miller et al.   MOLECULAR THERAPY

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

(2008) Elena E Perez et al.   NATURE BIOTECHNOLOGY

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases

(2008) Y. Santiago et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy

(2008) Saroj P. Mathupala et al.   SEMINARS IN CANCER BIOLOGY