Copper Deficiency Leads to Anemia, Duodenal Hypoxia, Upregulation of HIF-2α and Altered Expression of Iron Absorption Genes in Mice

The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption

(2013) Sheila A. Anderson et al.   Cell Metabolism

Copper deficiency has minimal impact on ferroportin expression or function

(2012) Joseph R. Prohaska et al.   BIOMETALS

Regulation of Heme Synthesis and Proteasomal Activity by Copper: Possible Implications for Wilson's Disease

(2012) Ravit Hait-Darshan et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Discovery of a cytosolic/soluble ferroxidase in rodent enterocytes

(2012) P. N. Ranganathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepcidin and iron regulation, 10 years later

(2011) T. Ganz   BLOOD

Duodenal cytochrome b (Cybrd 1) and HIF-2α expression during acute hypoxic exposure in mice

(2011) Gladys O. Latunde-Dada et al.   EUROPEAN JOURNAL OF NUTRITION

Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice

(2011) Matthew Taylor et al.   GASTROENTEROLOGY

Excess Copper Chelating Therapy for Wilson Disease Induces Anemia and Liver Dysfunction

(2011) Masaru Harada et al.   INTERNAL MEDICINE

Cellular Hypoxia of Pancreatic β-Cells Due to High Levels of Oxygen Consumption for Insulin Secretionin Vitro

(2011) Yoshifumi Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestinal Hypoxia-inducible Factor-2α (HIF-2α) Is Critical for Efficient Erythropoiesis

(2011) Erik R. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Cardiac Copper Deficiency Activates a Systemic Signaling Mechanism that Communicates with the Copper Acquisition and Storage Organs

(2010) Byung-Eun Kim et al.   Cell Metabolism

Metabolic crossroads of iron and copper

(2010) James F Collins et al.   NUTRITION REVIEWS

Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

(2009) Yatrik M. Shah et al.   Cell Metabolism

Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone1

(2009) S. L. Hansen et al.   JOURNAL OF ANIMAL SCIENCE

HIF-2α, but not HIF-1α, promotes iron absorption in mice

(2009) Maria Mastrogiannaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence for a critical role of ceruloplasmin oxidase activity in iron metabolism of Wilson disease gene knockout mice

(2009) Uta Merle et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepcidin Decreases Iron Transporter Expression in Vivo in Mouse Duodenum and Spleen and in Vitro in THP-1 Macrophages and Intestinal Caco-2 Cells

(2009) Bomee Chung et al.   JOURNAL OF NUTRITION

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

(2009) Gregg L. Semenza   PHYSIOLOGY

Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro

(2008) Steven Wyman et al.   FEBS LETTERS

Copper deficient rats and mice both develop anemia but only rats have lower plasma and brain iron levels

(2007) Joshua W. Pyatskowit et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY