γ-Tocotrienol Induces Paraptosis-Like Cell Death in Human Colon Carcinoma SW620 Cells

First Evidence That  -Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF- B Pathway

(2012) K. A. Manu et al.   CLINICAL CANCER RESEARCH

FH535 Inhibited Migration and Growth of Breast Cancer Cells

(2012) Joji Iida et al.   PLoS One

Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31

(2011) Hannah M. Heath-Engel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

γ-Tocotrienol Induces Apoptosis in Human T Cell Lymphoma through Activation of Both Intrinsic and Extrinsic Pathways

(2011) Chandan Wilankar et al.   CURRENT PHARMACEUTICAL DESIGN

The 21st Century Form of Vitamin E - Tocotrienol

(2011) Jayeeta Bardhan et al.   CURRENT PHARMACEUTICAL DESIGN

Interaction of natural products with cell survival and signaling pathways in the biochemical elucidation of drug targets in cancer

(2011) Yasrib Qurishi et al.   Future Oncology

Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide

(2011) Qing Jiang et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation

(2011) Xiangming Ji et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

γ-Tocotrienol inhibits angiogenesis of human umbilical vein endothelial cell induced by cancer cell

(2011) Yang Li et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells

(2011) Dorrelyn Patacsil et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Induction of Apoptosis byγ-Tocotrienol in Human Cancer Cell Lines and Leukemic Blasts From Patients: Dependency on Bid, Cytochromec, and Caspase Pathway

(2011) Akiko Inoue et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Effects of Epidural Capsaicin on Nociceptive Threshold and Neurological Functions in Rabbits

(2011) Ying-Wei Dong et al.   PAIN MEDICINE

A paraptosis-like cell death induced by δ-tocotrienol in human colon carcinoma SW620 cells is associated with the suppression of the Wnt signaling pathway

(2011) Jing-Shu Zhang et al.   TOXICOLOGY

Tocotrienols, the vitamin E of the 21st century: Its potential against cancer and other chronic diseases

(2010) Bharat B. Aggarwal et al.   BIOCHEMICAL PHARMACOLOGY

γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent

(2010) Peramaiyan Rajendran et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53

(2010) Binghui Li et al.   CANCER LETTERS

Targeting Wnt Signaling in Colon Cancer Stem Cells

(2010) E. M. F. de Sousa et al.   CLINICAL CANCER RESEARCH

Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers

(2010) D Mahalingam et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Tocotrienols Inhibited Growth and Induced Apoptosis in Human HeLa Cells Through the Cell Cycle Signaling Pathway

(2010) Shu-Jing Wu et al.   INTEGRATIVE CANCER THERAPIES

Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells

(2010) Jyoti Nautiyal et al.   INTERNATIONAL JOURNAL OF CANCER

Tocotrienol Distribution in Foods: Estimation of Daily Tocotrienol Intake of Japanese Population

(2010) Phumon Sookwong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

γ-Tocotrienol Promotes TRAIL-Induced Apoptosis through Reactive Oxygen Species/Extracellular Signal-Regulated Kinase/p53–Mediated Upregulation of Death Receptors

(2010) Ramaswamy Kannappan et al.   MOLECULAR CANCER THERAPEUTICS

Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis

(2010) Michael A. James et al.   MOLECULAR CARCINOGENESIS

Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin

(2010) E Lavergne et al.   ONCOGENE

γ-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line

(2010) Sheng Bi et al.   TOXICOLOGY

Monitoring early responses to irradiation with dual-tracer micro-PET in dual-tumor bearing mice

(2010) Hui Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Worldwide Variations in Colorectal Cancer

(2009) M. M. Center et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Caspase-Independent Pathways of Programmed Cell Death: The Unraveling of New Targets of Cancer Therapy?

(2009) C. Constantinou et al.   CURRENT CANCER DRUG TARGETS

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells

(2009) Mi Jin Yoon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibitory effects of γ-tocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells☆☆☆

(2009) Hui-Kun Liu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Inhibition of proliferation and induction of apoptosis by γ-tocotrienol in human colon carcinoma HT-29 cells

(2009) Wei-Li Xu et al.   NUTRITION

Suppression of Tumor Growth by Palm Tocotrienols Via the Attenuation of Angiogenesis

(2009) Wong Weng-Yew et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Induction of Caspase-Independent Programmed Cell Death by Vitamin E Natural Homologs and Synthetic Derivatives

(2009) Constantina Constantinou et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Wnt Signaling Is Regulated by Endoplasmic Reticulum Retention

(2009) J. Susie Zoltewicz et al.   PLoS One

Wnt/β-catenin signaling: new (and old) players and new insights

(2008) He Huang et al.   CURRENT OPINION IN CELL BIOLOGY

β-Ionone suppresses mammary carcinogenesis, proliferative activity and induces apoptosis in the mammary gland of the Sprague-Dawley rat

(2008) Jia-Ren Liu et al.   INTERNATIONAL JOURNAL OF CANCER

γ-Tocotrienol induces mitochondria-mediated apoptosis in human gastric adenocarcinoma SGC-7901 cells

(2008) Wenguang Sun et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A small-molecule inhibitor of Tcf/ -catenin signaling down-regulates PPAR  and PPAR  activities

(2008) S. Handeli et al.   MOLECULAR CANCER THERAPEUTICS