The role of the extracellular loops of the CGRP receptor, a family B GPCR

Lifting the lid on GPCRs: the role of extracellular loops

(2012) M Wheatley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function

(2011) James Barwell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs?

(2011) James Barwell et al.   BRITISH JOURNAL OF PHARMACOLOGY

Refinement of Glucagon-like Peptide 1 Docking to Its Intact Receptor Using Mid-region Photolabile Probes and Molecular Modeling

(2011) Laurence J. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shared and separate functions of the RAMP-based adrenomedullin receptors

(2011) Kenji Kuwasako et al.   PEPTIDES

Structural insights into RAMP modification of secretin family G protein-coupled receptors: implications for drug development

(2011) Julia K. Archbold et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonists in the Treatment of Migraine

(2010) Paul L. Durham et al.   CNS DRUGS

Secretin Occupies a Single Protomer of the Homodimeric Secretin Receptor Complex

(2010) Maoqing Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism

(2010) Ernst ter Haar et al.   STRUCTURE

The minor binding pocket: a major player in 7TM receptor activation

(2010) Mette M. Rosenkilde et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Regulation of signal transduction by calcitonin gene-related peptide receptors

(2010) Christopher S Walker et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Molecular Basis of Association of Receptor Activity-Modifying Protein 3 with the Family B G Protein-Coupled Secretin Receptor

(2009) Kaleeckal G. Harikumar et al.   BIOCHEMISTRY

Juxtamembranous Region of the Amino Terminus of the Family B G Protein-coupled Calcitonin Receptor Plays a Critical Role in Small-molecule Agonist Action

(2009) Maoqing Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alanine Scanning Mutagenesis of the Second Extracellular Loop of Type 1 Corticotropin-Releasing Factor Receptor Revealed Residues Critical for Peptide Binding

(2009) K. Gkountelias et al.   MOLECULAR PHARMACOLOGY

A  -Arrestin-Biased Agonist of the Parathyroid Hormone Receptor (PTH1R) Promotes Bone Formation Independent of G Protein Activation

(2009) D. Gesty-Palmer et al.   Science Translational Medicine

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?

(2009) Christoph Parthier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mapping Peptide Hormone−Receptor Interactions Using a Disulfide-Trapping Approach†

(2008) Paul Monaghan et al.   BIOCHEMISTRY

Class-B GPCR activation: is ligand helix-capping the key?

(2008) Jean-Michel Neumann et al.   TRENDS IN BIOCHEMICAL SCIENCES