A2A Adenosine Receptors Are Differentially Modulated by Pharmacological Treatments in Rheumatoid Arthritis Patients and Their Stimulation Ameliorates Adjuvant-Induced Arthritis in Rats

Leflunomide or methotrexate? Comparison of clinical efficacy and safety in low socio-economic rheumatoid arthritis patients

(2014) Muhammad Ishaq et al.   Modern Rheumatology

Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2011

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The Anti-Tumor Effect of A3 Adenosine Receptors Is Potentiated by Pulsed Electromagnetic Fields in Cultured Neural Cancer Cells

(2012) Fabrizio Vincenzi et al.   PLoS One

Adenosine A2A Receptor Activation Prevents Wear Particle-Induced Osteolysis

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Selective Activation of Adenosine A2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis

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Optimising treatment in rheumatoid arthritis: a review of potential biological markers of response

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Animal models for arthritis: innovative tools for prevention and treatment

(2011) G. Kollias et al.   ANNALS OF THE RHEUMATIC DISEASES

Disease activity score-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis: data from the GUEPARD trial and ESPOIR cohort

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Imaging studies in Freund's complete adjuvant model of regional polyarthritis, a model suitable for the study of pain mechanisms, in the rat

(2011) Lina Almarestani et al.   ARTHRITIS AND RHEUMATISM

Polydeoxyribonucleotide reduces cytokine production and the severity of collagen-induced arthritis by stimulation of adenosine A2A receptor

(2011) Alessandra Bitto et al.   ARTHRITIS AND RHEUMATISM

Biologics-Based Therapy for the Treatment of Rheumatoid Arthritis

(2011) D L Scott   CLINICAL PHARMACOLOGY & THERAPEUTICS

The −1082A/G polymorphism in the Interleukin-10 gene and the risk of rheumatoid arthritis: A meta-analysis

(2011) Jie Zhang et al.   CYTOKINE

Adenosine receptor targeting in health and disease

(2011) Stefania Gessi et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E2and cytokine release in human osteoarthritic synovial fibroblasts

(2011) A. Ongaro et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CGS 21680, an Agonist of the Adenosine (A2A) Receptor, Reduces Progression of Murine Type II Collagen-induced Arthritis

(2011) EMANUELA MAZZON et al.   JOURNAL OF RHEUMATOLOGY

The Pathogenesis of Rheumatoid Arthritis

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International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update

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Anti-Inflammatory and Immunosuppressive Effects of the A2AAdenosine Receptor

(2011) Gillian R. Milne et al.   TheScientificWorldJOURNAL

A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release

(2011) Katia Varani et al.   ARTHRITIS RESEARCH & THERAPY

Anti-inflammatory and antihyperalgesic effects of the combination of ibuprofen and hemin in adjuvant-induced arthritis in the Wistar rat

(2011) Shamsherjit Kaur et al.   INFLAMMOPHARMACOLOGY

Infection with an intestinal helminth parasite reduces Freund's complete adjuvant-induced monoarthritis in mice

(2010) Meiqing Shi et al.   ARTHRITIS AND RHEUMATISM

The role of adenosine receptors in rheumatoid arthritis

(2010) Katia Varani et al.   AUTOIMMUNITY REVIEWS

Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes

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A2A Receptor Ligands: Past, Present and Future Trends

(2010) C. Manera et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis

(2010) Hetal B. Patel et al.   FASEB JOURNAL

Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death

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Immunologic rheumatic disorders

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Targeting B cells in immune-mediated inflammatory disease: A comprehensive review of mechanisms of action and identification of biomarkers

(2010) Thomas Dörner et al.   PHARMACOLOGY & THERAPEUTICS

A Variant of TNFR2-Fc Fusion Protein Exhibits Improved Efficacy in Treating Experimental Rheumatoid Arthritis

(2010) Tong Yang et al.   PLoS Computational Biology

Normalization of A2Aand A3adenosine receptor up-regulation in rheumatoid arthritis patients by treatment with anti-tumor necrosis factor α but not methotrexate

(2009) Katia Varani et al.   ARTHRITIS AND RHEUMATISM

Enhanced pain perception in rheumatoid arthritis: Novel considerations

(2009) Patrick B. Wood   Current Pain and Headache Reports

The A2aR adenosine receptor controls cytokine production in iNKT cells

(2009) Michael Nowak et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adenosine receptor agonists for promotion of dermal wound healing

(2008) María D. Valls et al.   BIOCHEMICAL PHARMACOLOGY

An A2Aadenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models

(2008) Christopher C Moore et al.   BMC INFECTIOUS DISEASES