Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting M. tuberculosis QcrB

Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening

(2012) Sarah A. Stanley et al.   ACS Chemical Biology

A High-Throughput Screen To Identify Inhibitors of ATP Homeostasis in Non-replicating Mycobacterium tuberculosis

(2012) Puiying A. Mak et al.   ACS Chemical Biology

SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis

(2012) Kapil Tahlan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability

(2012) Michael S. Scherman et al.   BIOORGANIC & MEDICINAL CHEMISTRY

MmpL Genes Are Associated with Mycolic Acid Metabolism in Mycobacteria and Corynebacteria

(2012) Cristian Varela et al.   CHEMISTRY & BIOLOGY

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action

(2012) Katherine A Sacksteder et al.   Future Microbiology

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

(2012) Anna E Grzegorzewicz et al.   Nature Chemical Biology

Update in Tuberculosis and Nontuberculous Mycobacterial Disease 2010

(2011) Wing Wai Yew et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212

(2011) Valentina La Rosa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Totally Drug-Resistant Tuberculosis in India

(2011) Z. F. Udwadia et al.   CLINICAL INFECTIOUS DISEASES

The challenge of new drug discovery for tuberculosis

(2011) Anil Koul et al.   NATURE

High throughput screening of a library based on kinase inhibitor scaffolds against Mycobacterium tuberculosis H37Rv

(2011) Robert C. Reynolds et al.   TUBERCULOSIS

Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity

(2011) Garrett C. Moraski et al.   ACS Medicinal Chemistry Letters

Fast Standardized Therapeutic-Efficacy Assay for Drug Discovery against Tuberculosis

(2010) J. Rullas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

TMC207: the first compound of a new class of potent anti-tuberculosis drugs

(2010) Alberto Matteelli et al.   Future Microbiology

Drug-resistant tuberculosis: Past, present, future

(2010) Chen-Yuan CHIANG et al.   RESPIROLOGY

The Population Dynamics and Control of Tuberculosis

(2010) C. Dye et al.   SCIENCE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

(2009) Luke R. Odell et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antituberculosis activity of the molecular libraries screening center network library

(2009) Joseph A. Maddry et al.   TUBERCULOSIS

High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv

(2009) Subramaniam Ananthan et al.   TUBERCULOSIS

High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors

(2009) Thierry Christophe et al.   PLoS Pathogens

The Q-cycle reviewed: How well does a monomeric mechanism of the bc1 complex account for the function of a dimeric complex?

(2008) Antony R. Crofts et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

(2008) S. P. S. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA