The Relationship between Aggregation and Toxicity of Polyglutamine-Containing Ataxin-3 in the Intracellular Environment of Escherichia coli

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation

(2011) Jeannette Hübener et al.   BRAIN

Amyloid deposits: Protection against toxic protein species?

(2011) Sebastian Treusch et al.   CELL CYCLE

Bacterial Inclusion Bodies of Alzheimer's Disease β-Amyloid Peptides Can Be Employed To Study Native-Like Aggregation Intermediate States

(2011) Muralidhar Dasari et al.   CHEMBIOCHEM

Biological role of bacterial inclusion bodies: a model for amyloid aggregation

(2011) Elena García-Fruitós et al.   FEBS Journal

Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology

(2011) Pietro Gatti-Lafranconi et al.   FEBS Journal

The role of the central flexible region on the aggregation and conformational properties of human ataxin-3

(2011) Carlo Santambrogio et al.   FEBS Journal

Structural Characterization of Polyglutamine Fibrils by Solid-State NMR Spectroscopy

(2011) Robert Schneider et al.   JOURNAL OF MOLECULAR BIOLOGY

Aβ40 and Aβ42 Amyloid Fibrils Exhibit Distinct Molecular Recycling Properties

(2011) Laia Sánchez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Major Role for Side-Chain Polyglutamine Hydrogen Bonding in Irreversible Ataxin-3 Aggregation

(2011) Antonino Natalello et al.   PLoS One

Macromolecular crowding converts the human recombinant PrPC to the soluble neurotoxic β-oligomers

(2010) Liqin Huang et al.   FASEB JOURNAL

Functional interactions as a survival strategy against abnormal aggregation

(2010) Masino Laura et al.   FASEB JOURNAL

Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool

(2010) Maya A. Olshina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Low-Level Expression of a Folding-Incompetent Protein in Escherichia coli: Search for the Molecular Determinants of Protein Aggregation In Vivo

(2010) Julia Winkelmann et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative Relationships between Huntingtin Levels, Polyglutamine Length, Inclusion Body Formation, and Neuronal Death Provide Novel Insight into Huntington's Disease Molecular Pathogenesis

(2010) J. Miller et al.   JOURNAL OF NEUROSCIENCE

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Formation and Toxicity of Soluble Polyglutamine Oligomers in Living Cells

(2010) Patrick Lajoie et al.   PLoS One

Solid-State NMR Spectroscopy Reveals thatE. coliInclusion Bodies of HET-s(218-289) are Amyloids

(2009) Christian Wasmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fibril Fragmentation Enhances Amyloid Cytotoxicity

(2009) Wei-Feng Xue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

(2009) Ashwani K Thakur et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

(2009) Jennifer L. Tomic et al.   NEUROBIOLOGY OF DISEASE

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins

(2009) H. M. Saunders et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Amyloids in bacterial inclusion bodies

(2009) Natalia S. de Groot et al.   TRENDS IN BIOCHEMICAL SCIENCES

Orthogonal Cross-Seeding: An Approach To Explore Protein Aggregates In Living Cells†

(2008) Justyna Hinz et al.   BIOCHEMISTRY

Inclusion bodies: Specificity in their aggregation process and amyloid-like structure

(2008) Montse Morell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effects of recombinant protein misfolding and aggregation on bacterial membranes

(2008) D. Ami et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Studies on bacterial inclusion bodies

(2008) Natalia S de Groot et al.   Future Microbiology

Sequence Determinants of Bacterial Amyloid Formation

(2008) Xuan Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

In vivo aggregation of bovine β-lactoglobulin is affected by Cys at position 121

(2008) Gaetano Invernizzi et al.   PROTEIN EXPRESSION AND PURIFICATION