The role of the central flexible region on the aggregation and conformational properties of human ataxin-3

The Josephin Domain Determines the Morphological and Mechanical Properties of Ataxin-3 Fibrils

(2011) Laura Masino et al.   BIOPHYSICAL JOURNAL

N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation

(2011) Jeannette Hübener et al.   BRAIN

Characterization of β2-microglobulin conformational intermediates associated to different fibrillation conditions

(2011) Carlo Santambrogio et al.   JOURNAL OF MASS SPECTROMETRY

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein

(2011) Lucy A Woods et al.   Nature Chemical Biology

A Major Role for Side-Chain Polyglutamine Hydrogen Bonding in Irreversible Ataxin-3 Aggregation

(2011) Antonino Natalello et al.   PLoS One

Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death

(2010) Ana-João Rodrigues et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Functional interactions as a survival strategy against abnormal aggregation

(2010) Masino Laura et al.   FASEB JOURNAL

Amyloid oligomers: dynamics and toxicity in the cytosol and nucleus

(2010) Akira Kitamura et al.   FEBS Journal

Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity

(2010) Massimo Stefani   FEBS Journal

Intrinsic disorder in proteins associated with neurodegenerative diseases

(2010) Vladimir et al.   Frontiers in Bioscience-Landmark

Mass spectrometry and the amyloid problem—How far can we go in the gas phase?

(2010) Alison E. Ashcroft   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Structural Transformation of the Tandem Ubiquitin-Interacting Motifs in Ataxin-3 and Their Cooperative Interactions with Ubiquitin Chains

(2010) Ai-Xin Song et al.   PLoS One

Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation

(2010) A. L. Robertson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrospray-ionization mass spectrometry as a tool for fast screening of protein structural properties

(2009) Rita Grandori et al.   Biotechnology Journal

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

(2009) Ashwani K Thakur et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins

(2009) H. M. Saunders et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Conformational Plasticity of the Gerstmann–Sträussler–Scheinker Disease Peptide as Indicated by Its Multiple Aggregation Pathways

(2008) Antonino Natalello et al.   JOURNAL OF MOLECULAR BIOLOGY

Do Ionic Charges in ESI MS Provide Useful Information on Macromolecular Structure?

(2008) I KALTASHOV et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

FTIR reveals structural differences between native β-sheet proteins and amyloid fibrils

(2004) Giorgia Zandomeneghi et al.   PROTEIN SCIENCE