Amyloid Beta Precursor Protein and Prion Protein Have a Conserved Interaction Affecting Cell Adhesion and CNS Development

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

(2012) Oliver D. King et al.   BRAIN RESEARCH

Memory Deficits of British Dementia Knock-In Mice Are Prevented by A -Precursor Protein Haploinsufficiency

(2012) R. Tamayev et al.   JOURNAL OF NEUROSCIENCE

Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain

(2012) Victoria Lewis et al.   PLoS One

A  neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

(2012) H. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tol2gene trap integrations in the zebrafish amyloid precursor protein genesappaandaplp2reveal accumulation of secreted APP at the embryonic veins

(2011) Hsin-Kai Liao et al.   DEVELOPMENTAL DYNAMICS

An N-terminal Polybasic Domain and Cell Surface Localization Are Required for Mutant Prion Protein Toxicity

(2011) Isaac H. Solomon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A  Inhibition of Ionic Conductance in Mouse Basal Forebrain Neurons Is Dependent upon the Cellular Prion Protein PrPC

(2011) K. Alier et al.   JOURNAL OF NEUROSCIENCE

Drosophila Amyloid Precursor Protein-Like Is Required for Long-Term Memory

(2011) V. Goguel et al.   JOURNAL OF NEUROSCIENCE

Ablation of Cellular Prion Protein Does Not Ameliorate Abnormal Neural Network Activity or Cognitive Dysfunction in the J20 Line of Human Amyloid Precursor Protein Transgenic Mice

(2011) M. Cisse et al.   JOURNAL OF NEUROSCIENCE

Prion protein at the crossroads of physiology and disease

(2011) Emiliano Biasini et al.   TRENDS IN NEUROSCIENCES

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

(2011) Darragh B. Freir et al.   Nature Communications

The role of RNA in mammalian prion protein conversion

(2011) Mariana P. B. Gomes et al.   Wiley Interdisciplinary Reviews-RNA

Tau, prions and Aβ: the triad of neurodegeneration

(2010) Lilla Reiniger et al.   ACTA NEUROPATHOLOGICA

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples

(2010) Douglas B. Kell   ARCHIVES OF TOXICOLOGY

Investigating regeneration and functional integration of CNS neurons: Lessons from zebrafish genetics and other fish species

(2010) Valerie C. Fleisch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an alzheimer's disease model mouse

(2010) Erika Chung et al.   BMC NEUROSCIENCE

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Prion protein and Aβ-related synaptic toxicity impairment

(2010) Anna Maria Calella et al.   EMBO Molecular Medicine

Prion protein and RNA: a view from the cytoplasm

(2010) Xavier Roucou   Frontiers in Bioscience-Landmark

Familial Alzheimer's disease and inherited prion disease in the UK are poorly ascertained

(2010) J. C. Stevens et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein

(2010) D. A. Gimbel et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Mechanisms of AD neurodegeneration may be independent of Aβ and its derivatives

(2010) Nikolaos K. Robakis   NEUROBIOLOGY OF AGING

Uncovering Molecular Biomarkers That Correlate Cognitive Decline with the Changes of Hippocampus' Gene Expression Profiles in Alzheimer's Disease

(2010) Martín Gómez Ravetti et al.   PLoS One

Early Embryonic Gene Expression Profiling of Zebrafish Prion Protein (Prp2) Morphants

(2010) Rasoul Nourizadeh-Lillabadi et al.   PLoS One

Prion protein and Alzheimer disease

(2010) Katherine A.B. Kellett et al.   Prion

PrPs

(2010) Edward Málaga-Trillo et al.   Prion

Synthetic amyloid-  oligomers impair long-term memory independently of cellular prion protein

(2010) C. Balducci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease

(2010) Victoria M. Perreau et al.   PROTEOMICS

New insights into cellular prion protein (PrPc) functions: The “ying and yang” of a relevant protein

(2009) Oriol Nicolas et al.   BRAIN RESEARCH REVIEWS

Amyloid precursor protein is required for convergent-extension movements during Zebrafish development

(2009) Powrnima Joshi et al.   DEVELOPMENTAL BIOLOGY

β-amyloid oligomers and cellular prion protein in Alzheimer’s disease

(2009) Erik C. Gunther et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Recent advances in our understanding of neurodegeneration

(2009) Kurt A. Jellinger   JOURNAL OF NEURAL TRANSMISSION

Quantitative Reverse-Transcription Polymerase Chain Reaction Analysis of Alzheimer's-Associated Genes in Mouse Scrapie

(2009) Sarah Medina et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Regulation of Embryonic Cell Adhesion by the Prion Protein

(2009) Edward Málaga-Trillo et al.   PLOS BIOLOGY

Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones

(2009) Joel C. Watts et al.   PLoS Pathogens

The Prion's Elusive Reason for Being

(2008) Adriano Aguzzi et al.   Annual Review of Neuroscience

No Association between CALHM1 and Alzheimer's Disease Risk

(2008) Lars Bertram et al.   CELL

Controlling morpholino experiments: don't stop making antisense

(2008) J. S. Eisen et al.   DEVELOPMENT

Protocadherin-18a has a role in cell adhesion, behavior and migration in zebrafish development

(2008) Emil Aamar et al.   DEVELOPMENTAL BIOLOGY

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

(2008) Konstanze F Winklhofer et al.   EMBO JOURNAL

Stress-protective signalling of prion protein is corrupted by scrapie prions

(2008) Angelika S Rambold et al.   EMBO JOURNAL

Homophilic Interactions of the Amyloid Precursor Protein (APP) Ectodomain Are Regulated by the Loop Region and Affect β-Secretase Cleavage of APP

(2008) Daniela Kaden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

(2008) Houman Khosravani et al.   JOURNAL OF CELL BIOLOGY

First Report of Creutzfeldt-Jakob Disease Occurring in 2 Siblings Unexplained byPRNPMutation

(2008) Thomas E.F. Webb et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines

(2008) Oleg Broytman et al.   NEUROBIOLOGY OF AGING

Prion protein aggresomes are poly(A)+ ribonucleoprotein complexes that induce a PKR-mediated deficient cell stress response

(2007) Kevin Goggin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH