Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing

A longer and healthier life with TOR down-regulation: genetics and drugs: Figure 1

(2011) Ivana Bjedov et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Modelling gene and protein regulatory networks with Answer Set Programming

(2011) Timur Fayruzov et al.   International Journal of Data Mining and Bioinformatics

Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

(2011) N. Alic et al.   Molecular Systems Biology

Deep proteome and transcriptome mapping of a human cancer cell line

(2011) N. Nagaraj et al.   Molecular Systems Biology

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor

(2010) Nazif Alic et al.   AGING CELL

Logic-Based Models for the Analysis of Cell Signaling Networks

(2010) Melody K. Morris et al.   BIOCHEMISTRY

Discovering modulators of gene expression

(2010) Özgün Babur et al.   NUCLEIC ACIDS RESEARCH

Computational biology for ageing

(2010) D. Wieser et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

(2010) C. Kenyon   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Modelling the Response of FOXO Transcription Factors to Multiple Post-Translational Modifications Made by Ageing-Related Signalling Pathways

(2010) Graham R. Smith et al.   PLoS One

Mathematical Modelling of Cell-Fate Decision in Response to Death Receptor Engagement

(2010) Laurence Calzone et al.   PLoS Computational Biology

Dynamic Switch of Negative Feedback Regulation in Drosophila Akt–TOR Signaling

(2010) Lutz Kockel et al.   PLoS Genetics

Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk

(2010) Cathy Slack et al.   PLoS Genetics

Molecular mechanisms of metabolic regulation by insulin inDrosophila

(2009) Aurelio A. Teleman   BIOCHEMICAL JOURNAL

Logical modelling of regulatory networks with GINsim 2.3

(2009) A. Naldi et al.   BIOSYSTEMS

BioQuali Cytoscape plugin: analysing the global consistency of regulatory networks

(2009) Carito Guziolowski et al.   BMC GENOMICS

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction

(2009) Julio Saez-Rodriguez et al.   Molecular Systems Biology

Genome-wide identification of post-translational modulators of transcription factor activity in human B cells

(2009) Kai Wang et al.   NATURE BIOTECHNOLOGY

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

The Drosophila SH2B Family Adaptor Lnk Acts in Parallel to Chico in the Insulin Signaling Pathway

(2009) Christian Werz et al.   PLoS Genetics

14-3-3ɛ antagonizes FoxO to control growth, apoptosis and longevity inDrosophila

(2008) Mette Damgaard Nielsen et al.   AGING CELL

Modeling Biological Networks by Action Languages via Answer Set Programming

(2008) Steve Dworschak et al.   CONSTRAINTS

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

(2007) Colin Selman et al.   FASEB JOURNAL