The Tempered Polymerization of Human Neuroserpin

Molecular basis of α1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer

(2011) Masayuki Yamasaki et al.   EMBO REPORTS

Existence of Metastable Intermediate Lysozyme Conformation Highlights the Role of Alcohols in Altering Protein Stability

(2011) Michele D′Amico et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization

(2011) Beena Krishnan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

On the molecular structure of human neuroserpin polymers

(2011) Maria Grazia Santangelo et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Two Latent and Two Hyperstable Polymeric Forms of Human Neuroserpin

(2010) Stefano Ricagno et al.   BIOPHYSICAL JOURNAL

A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1-antitrypsin deficiency

(2010) Elena Miranda et al.   HEPATOLOGY

Defining the mechanism of polymerization in the serpinopathies

(2010) U. I. Ekeowa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational Pathology of the Serpins: Themes, Variations, and Therapeutic Strategies

(2009) Bibek Gooptu et al.   Annual Review of Biochemistry

Probing Neuroserpin Polymerization and Interaction with Amyloid-β Peptides Using Single Molecule Fluorescence

(2009) Albert Chiou et al.   BIOPHYSICAL JOURNAL

Branching in Amyloid Fibril Growth

(2009) Christian Beyschau Andersen et al.   BIOPHYSICAL JOURNAL

Fibril Fragmentation Enhances Amyloid Cytotoxicity

(2009) Wei-Feng Xue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroserpin Polymers Activate NF-κB by a Calcium Signaling Pathway That Is Independent of the Unfolded Protein Response

(2009) Mark J. Davies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Neuroserpin: Structure and Time-Dependent Inhibition

(2009) Stefano Ricagno et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein stability modulated by a conformational effector: effects of trifluoroethanol on bovine serum albumin

(2009) Rita Carrotta et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB

(2008) E. Miranda et al.   HUMAN MOLECULAR GENETICS

The Structural Basis of Serpin Polymerization Studied by Hydrogen/Deuterium Exchange and Mass Spectrometry

(2008) Yuko Tsutsui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization

(2008) Masayuki Yamasaki et al.   NATURE