Review
Medicine, General & Internal
David Nunan, Ting Cai, Antoni D. Gardener, Jose M. Ordonez-Mena, Nia W. Roberts, Elizabeth T. Thomas, Kamal R. Mahtani
Summary: This study evaluated the benefits and harms of physical activity interventions in adults with irritable bowel syndrome (IBS) based on 11 randomized controlled trials. The results suggest that physical activity may improve symptoms of IBS, but the effects on quality of life and abdominal pain are uncertain. The certainty of evidence is very low, indicating a need for higher quality research in this area.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2022)
Review
Nutrition & Dietetics
Marcelina Radziszewska, Joanna Smarkusz-Zarzecka, Lucyna Ostrowska
Summary: Irritable Bowel Syndrome (IBS) is a chronic digestive disorder that is diagnosed based on the Rome IV criteria. People with IBS often associate their symptoms with the food they eat, leading to dietary restrictions. The FODMAP diet is currently recommended for IBS patients, but it may not work for everyone. Other unconventional diets lack research support and may worsen nutritional status. Physical activity and supplementation, such as probiotics and vitamin D, can be beneficial for managing IBS symptoms. This review aims to analyze the impact of various food items, physical activity, and dietary supplementation on the course of IBS.
Article
Sport Sciences
Martin Bahls, Till Ittermann, Ralf Ewert, Beate Stubbe, Henry Voelzke, Nele Friedrich, Stephan B. Felix, Marcus Doerr
Summary: The study suggests that sports and leisure time related physical activity may attenuate the age-related decline in cardiorespiratory fitness, while work-related physical activity was not associated with CRF.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Gastroenterology & Hepatology
Vivek C. Goodoory, Lesley A. Houghton, Yan Yiannakou, Christopher J. Black, Alexander C. Ford
Summary: This study found that the natural history of irritable bowel syndrome (IBS) defined according to the Rome IV criteria is more severe compared to IBS defined by the Rome III criteria. Approximately 60% of the participants met the Rome IV criteria, while approximately 40% met the Rome III criteria. Individuals with Rome IV IBS were more likely to seek medical care, start new treatments, and have more treatment cycles compared to those with Rome III IBS. Additionally, Rome IV IBS patients had more severe symptoms, greater impact on daily activities, and poorer psychological health.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Medicine, General & Internal
Jiaqu Cui, Zhiliang Lin, Hongliang Tian, Bo Yang, Di Zhao, Chen Ye, Ning Li, Huanlong Qin, Qiyi Chen
Summary: This study aimed to investigate the long-term efficacy of fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome (IBS). The results from a 60-month follow-up period established the safety and efficacy of FMT for IBS, but highlighted the need for periodic and repetitive treatments to maintain the sustained effect.
FRONTIERS IN MEDICINE
(2021)
Article
Clinical Neurology
Berta Portugal, Fanny Artaud, Isabelle Degaey, Emmanuel Roze, Agnes Fournier, Gianluca Severi, Marianne Canonico, Cecile Proust-Lima, Alexis Elbaz
Summary: By studying women and using lagged analyses to address reverse causation, this study found that higher physical activity level is associated with lower incidence of Parkinson's disease (PD), which is important for PD prevention interventions.
Article
Gastroenterology & Hepatology
Giovanni Marasco, Cesare Cremon, Maria Raffaella Barbaro, Giulia Cacciari, Francesca Falangone, Anna Kagramanova, Dmitry Bordin, Vasile Drug, Egidia Miftode, Pietro Fusaroli, Salem Youssef Mohamed, Chiara Ricci, Massimo Bellini, Mohammed Masudur Rahman, Luigi Melcarne, Javier Santos, Beatriz Lobo, Serhat Bor, Suna Yapali, Deniz Akyol, Ferdane Pirincci Sapmaz, Yonca Yilmaz Urun, Tugce Eskazan, Altay Celebi, Huseyin Kacmaz, Berat Ebik, Hatice Cilem Binicier, Mehmet Sait Bugdayci, Munkhtsetseg Banzragch Yagci, Husnu Pullukcu, Berrin Yalinbas Kaya, Ali Tureyen, Ibrahim Hatemi, Elif Sitre Koc, Goktug Sirin, Ali Riza Caliskan, Goksel Bengi, Esra Ergun Alis, Snezana Lukic, Meri Trajkovska, Keren Hod, Dan Dumitrascu, Antonello Pietrangelo, Elena Corradini, Magnus Simren, Jessica Sjoelund, Navkiran Tornkvist, Uday C. Ghoshal, Olga Kolokolnikova, Antonio Colecchia, Jordi Serra, Giovanni Maconi, Roberto De Giorgio, Silvio Danese, Piero Portincasa, Antonio Di Sabatino, Marcello Maggio, Elena Philippou, Yeong Yeh Lee, Daniele Salvi, Alessandro Venturi, Claudio Borghi, Marco Zoli, Paolo Gionchetti, Pierluigi Viale, Vincenzo Stanghellini, Giovanni Barbara
Summary: This study aimed to evaluate the prevalence of gastrointestinal symptoms and post-COVID-19 disorders of gut-brain interaction among hospitalized patients with SARS-CoV-2 infection. The results showed that patients with COVID-19 had higher rates of gastrointestinal symptoms on hospital admission and lower rates of constipation and hard stools at 12 months post-infection compared to the control group. Additionally, the rate of irritable bowel syndrome was significantly higher in patients with COVID-19 than in controls.
Article
Multidisciplinary Sciences
Agata Furgala, Katarzyna Ciesielczyk, Magdalena Przybylska-Felus, Konrad Jablonski, Krzysztof Gil, Malgorzata Zwolinska-Wcislo
Summary: This study aimed to assess the postprandial response, including gut peptide secretion and gastric myoelectric activity, in patients with constipation-predominant irritable bowel syndrome (IBS-C). The results showed that IBS-C patients had significantly elevated preprandial levels of gastrin and insulin, while VIP and ghrelin levels were decreased. Moreover, the gastric motility was impaired in IBS-C patients. These findings suggest that disturbances in the postprandial concentration of gut peptides may contribute to abnormal gastric function and intestinal motility, leading to exacerbation of clinical symptoms in IBS patients.
SCIENTIFIC REPORTS
(2023)
Review
Gastroenterology & Hepatology
Schin Bek, Yao Neng Teo, Xin-Hui Tan, Kristie H. R. Fan, Kewin Tien Ho Siah
Summary: Patients with irritable bowel syndrome (IBS) are at risk of developing micronutrient deficiencies, especially in vitamin B1, B2, calcium, iron, and zinc, due to exclusion diets. Dietary management of IBS patients should include a dietitian review to ensure nutritional adequacy.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Nutrition & Dietetics
Jorge Subias-Perie, David Navarrete-Villanueva, Angel Ivan Fernandez-Garcia, Ana Moradell, Eva Gesteiro, Jorge Perez-Gomez, Ignacio Ara, German Vicente-Rodriguez, Jose Antonio Casajus, Alba Gomez-Cabello
Summary: Metabolic syndrome has a high prevalence in Spanish older adults, but varies with different definitions. Sex and frailty do not appear to influence the development of MetS. However, physical activity seems to decrease the risk of central obesity, hypertension, and developing MetS.
Article
Clinical Neurology
Andre O. Werneck, Felipe B. Schuch, Davy Vancampfort, Brendon Stubbs, Paulo A. Lotufo, Isabela Bensenor, Megan Teychenne, Andre R. Brunoni
Summary: This study investigated the dose-response relationships between different types of physical activity (total, leisure-time, and transport) and the incidence of clinical depression. The results indicated that greater volumes of total and leisure-time physical activity were associated with a lower risk of developing clinical depression, even at lower doses. However, transport-related physical activity only showed protection at the lower category.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Gastroenterology & Hepatology
Michael Camilleri, Guy Boeckxstaens
Summary: This article evaluates the evidence that targeted pathophysiological mechanisms and customized treatments can be an alternative approach to treating patients with irritable bowel syndrome (IBS). The authors conducted a literature review on the mechanisms and treatments of IBS, identifying various noninvasive clinical tests that can assess the underlying mechanisms responsible for symptom generation. These mechanisms include rectal evacuation disorders, abnormal transit, visceral hypersensitivity or hypervigilance, bile acid diarrhea, sugar intolerances, barrier dysfunction, the microbiome, immune activation, and chemicals released by these mechanisms. The authors also recognized the basic molecular mechanisms contributing to these pathophysiologies, offering opportunities for interventions with medications targeted at specific food components, receptors, and potentially the microbiome. Although the evidence supporting interventions for each mechanism varies, the current state-of-the-art allows for a shift from symptom-based treatment to individualized treatment guided by pathophysiology and clinically identified biomarkers.
Article
Gastroenterology & Hepatology
Colleen H. Parker, Bruce D. Naliboff, Wendy Shih, Angela P. Presson, Lisa Kilpatrick, Arpana Gupta, Cathy Liu, Laurie A. Keefer, Jenny S. Sauk, Robert Hirten, Bruce E. Sands, Lin Chang
Summary: The study found that resilience is lower in patients with Irritable Bowel Syndrome (IBS) compared to the general population, leading to more severe symptoms. The impact of global mental health on resilience is more significant in IBS compared to the general population, and early adverse life events also decrease the ability to bounce back from adversity. While resilience in IBS is lower than the general US population, it is comparable to other chronic gastrointestinal conditions.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Nutrition & Dietetics
Francesca Curci, Filomena Corbo, Maria Lisa Clodoveo, Lara Salvagno, Antonio Rosato, Ivan Corazza, Roberta Budriesi, Matteo Micucci, Laura Beatrice Mattioli
Summary: This study examined the potential of olive-oil waste water as a food supplement for patients with irritable bowel syndrome. The results showed that Plus30 exhibited excellent antioxidant activity and had significant effects on microorganisms, making it a promising candidate for IBS patients as a food supplement.
Article
Cardiac & Cardiovascular Systems
Piero Clavario, Vincenzo De Marzo, Roberta Lotti, Cristina Barbara, Annalisa Porcile, Carmelo Russo, Federica Beccaria, Marco Bonavia, Luigi Carlo Bottaro, Marta Caltabellotta, Flavia Chioni, Monica Santangelo, Arto J. Hautala, Raffaele Griffo, Gianfranco Parati, Ugo Corra, Italo Porto
Summary: The study found that three months after discharge, about one-third of COVID-19 survivors may experience impaired cardiopulmonary function, leading to muscle functional limitations. Multivariate analysis showed that lung function, CO diffusion capacity, and DLE maximal strength were associated with pVO2.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Gastroenterology & Hepatology
Per-Ove Stotzer, Hasse Abrahamsson, Antal Bajor, Anders Kilander, Riadh Sadik, Henrik Sjovall, Magnus Simren
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2015)
Article
Surgery
Per Hedenstrom, Hanns-Ulrich Marschall, Bengt Nilsson, Akif Demir, Bjorn Lindkvist, Ola Nilsson, Riadh Sadik
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2018)
Article
Gastroenterology & Hepatology
Per Hedenstrom, Bengt Nilsson, Akif Demir, Carola Andersson, Fredrik Enlund, Ola Nilsson, Riadh Sadik
WORLD JOURNAL OF GASTROENTEROLOGY
(2017)
Article
Oncology
Karolina S. Jabbar, Liisa Arike, Caroline S. Verbeke, Riadh Sadik, Gunnar C. Hansson
JOURNAL OF CLINICAL ONCOLOGY
(2018)
Article
Gastroenterology & Hepatology
Elisabet Johannesson, Magnus Simren, Hans Strid, Antal Bajor, Riadh Sadik
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2011)
Article
Gastroenterology & Hepatology
Hans Tornblom, Lukas Van Oudenhove, Riadh Sadik, Hasse Abrahamsson, Jan Tack, Magnus Simren
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2012)
Article
Gastroenterology & Hepatology
Maria Benito de Valle, Tobias Mueller, Einar Bjoernsson, Morgane Otten, Martin Volkmann, Olaf Guckelberger, Bertram Wiedenmann, Riadh Sadik, Eckart Schott, Mats Andersson, Thomas Berg, Bjoern Lindkvist
DIGESTIVE AND LIVER DISEASE
(2014)
Article
Oncology
Karolina S. Jabbar, Caroline Verbeke, Anders G. Hyltander, Henrik Sjovall, Gunnar C. Hansson, Riadh Sadik
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2014)
Letter
Oncology
Karolina S. Jabbar, Caroline Verbeke, Anders G. Hyltander, Henrik Sjovall, Gunar C. Hanson, Riadh Sadik
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2014)
Article
Gastroenterology & Hepatology
Hans Strid, Magnus Simren, Stine Storsrud, Per-Ove Stotzer, Riadh Sadik
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2011)
Article
Gastroenterology & Hepatology
Perjohan Lindfors, Hans Tornblom, Riadh Sadik, Einar S. Bjornsson, Hasse Abrahamsson, Magnus Simren
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2012)
Article
Gastroenterology & Hepatology
Riadh Sadik, Evangelos Kalaitakis, Anders Thune, Jan Hansen, Claes Jonson
WORLD JOURNAL OF GASTROENTEROLOGY
(2011)
Article
Nursing
Elisabet Johannesson, Eva Jakobsson Ung, Gisela Ringstrom, Riadh Sadik
JOURNAL OF CLINICAL NURSING
(2019)
Article
Gastroenterology & Hepatology
Per Hedenstrom, Vasilis Chatzikyriakos, Roozbeh Shams, Catarina Lewerin, Riadh Sadik
Summary: This study evaluated the accuracy and safety of EUS-guided fine-needle biopsy sampling (EUS-FNB) in intrathoracic and intraabdominal lymphadenopathy, showing that both EUS-FNB and EUS-FNA are safe and highly sensitive for detecting metastatic lymph nodes, but diagnosing lymphoma remains challenging regardless of the needle used.
CLINICAL ENDOSCOPY
(2021)