Article
Multidisciplinary Sciences
Julia Diaz-Escobar, Nelson E. Ordonez-Guillen, Salvador Villarreal-Reyes, Alejandro Galaviz-Mosqueda, Vitaly Kober, Raul Rivera-Rodriguez, Jose E. Lozano Rizk
Summary: The study evaluates and compares deep-learning techniques for detecting COVID-19 infections from lung ultrasound imagery. The findings suggest that the InceptionV3 network provides the most promising predictive results, which can be used to further develop a viable computer-assisted screening tool for COVID-19 based on ultrasound imagery.
Article
Cardiac & Cardiovascular Systems
Donna M. Mancini, Danielle L. Brunjes, Anuradha Lala, Maria Giovanna Trivieri, Johanna P. Contreras, Benjamin H. Natelson
Summary: The study showed that circulatory impairment, abnormal ventilatory pattern, and ME/CFS are common in patients with PASC. Dysfunctional breathing, resting hypocapnia, and ME/CFS may contribute to symptoms. CPET is a valuable tool for assessing these patients.
JACC-HEART FAILURE
(2021)
Article
Virology
Enric Monreal, Sainz S. de la Maza, Pedro Gullon, Elena Natera-Villalba, Juan Luis Chico-Garcia, Alvaro Beltran-Corbellini, Javier Martinez-Sanz, Nuria Garcia-Barragan, Javier Buisan, Rafael Toledano, Araceli Alonso-Canovas, Paula Perez-Torre, Maria C. Matute-Lozano, Jose Luis Lopez-Sendon, Guillermo Garcia-Ribas, Inigo Corral, Jesus Fortun, Beatriz Montero-Errasquin, Luis Manzano, Luis Maiz-Carro, Lucienne Costa-Frossard, Jaime Masjuan
Summary: This study found that immunosuppression may reduce the risk of moderate to severe ARDS in COVID-19 patients, especially among those with autoimmune diseases.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Review
Food Science & Technology
Suelen Neris Almeida Viana, Tamires do Reis Santos Pereira, Janaina de Carvalho Alves, Caroline Tianeze de Castro, Lucas Santana C. da Silva, Lucio Henrique Sousa Pinheiro, Mariana Nougalli Roselino
Summary: This study found that probiotics, as adjunctive treatment for COVID-19 patients, are effective in reducing symptoms and improving cough, headaches, and diarrhea.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Virology
Zhiyong Han, Fortunato Battaglia, Stanley R. Terlecky
Summary: Some discharged COVID-19 patients are testing positive for SARS-CoV-2 RNA again, but it is unclear if they are contagious. Timely parallel testing of different samples is needed for further understanding.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Xu Yuyun, Yu Lexi, Wang Haochu, Shu Zhenyu, Gong Xiangyang
Summary: The study found differences in lung involvement between ordinary and severe/critical COVID-19 patients at different time points. Quantitative analysis based on chest CT images can provide early warning information for potentially severe/critical patients.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Respiratory System
Sabina A. Guler, Lukas Ebner, Catherine Aubry-Beigelman, Pierre-Olivier Bridevaux, Martin Brutsche, Christian Clarenbach, Christian Garzoni, Thomas K. Geiser, Alexandra Lenoir, Marco Mancinetti, Bruno Naccini, Sebastian R. Ott, Lise Piquilloud, Maura Prella, Yok-Ai Que, Paula M. Soccal, Christophe von Garnier, Manuela Funke-Chambour
Summary: The Swiss COVID-19 lung study investigated pulmonary sequelae of COVID-19 in 113 survivors. Severe/critical COVID-19 was associated with significant functional and radiological abnormalities 4 months after infection, potentially due to small-airway and lung parenchymal disease. Systematic follow-up for survivors needs to be evaluated to optimize care for patients recovering from COVID-19.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Multidisciplinary Sciences
Aziza Kantri, Jihane Ziati, Mohamed Khalis, Amal Haoudar, Karim El Aidaoui, Youssef Daoudi, Inas Chikhaoui, Khalid El Yamani, Mohammed Mouhaoui, Jalila El Bakkouri, Nezha Dini, Mohammed Mahi, Abdelhamid Naitlho, Abdelkrim Bahlaoui, Ahmed Bennana, Mustapha Noussair, Lahcen Belyamani, Chafik El Kettani
Summary: This study critically analyzed the clinical and biological characteristics of 134 patients from the North African Mediterranean region with COVID-19, finding that factors such as age, comorbidities, gender, and infection type were associated with disease progression to a severe state. Abnormalities in certain parameters were closely linked to disease deterioration.
Article
Virology
Ana B. Gorini da Veiga, Leticia G. Martins, Irina Riediger, Alix Mazetto, Maria do Carmo Debur, Tatiana S. Gregianini
Summary: Respiratory viral infections can be severe, especially for children, elderly, and patients with comorbidities. In Brazil, the official surveillance system investigates various viruses, but some cases with no identified pathogens remain. This study analyzed viruses in patients without underlying diseases, revealing the potential for coronaviruses to cause severe disease in healthy adults.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Fatima Higuera-de-la-Tijera, Alfredo Servin-Caamano, Daniel Reyes-Herrera, Argelia Flores-Lopez, Enrique J. A. Robiou-Vivero, Felipe Martinez-Rivera, Victor Galindo-Hernandez, Victor H. Rosales-Salyano, Catalina Casillas-Suarez, Oscar Chapa-Azuela, Alfonso Chavez-Morales, Billy Jimenez-Bobadilla, Maria L. Hernandez-Medel, Benjamin Orozco-Zuniga, Jed R. Zacarias-Ezzat, Santiago Camacho, Jose L. Perez-Hernandez
Summary: In COVID-19 patients, elevated AST levels, D-dimer levels, and age at admission can efficiently predict the need for ICU admission.
Article
Medicine, General & Internal
Liran Levy, Ofir Deri, Ella Huszti, Eyal Nachum, Stephane Ledot, Nir Shimoni, Milton Saute, Leonid Sternik, Ran Kremer, Yigal Kassif, Nona Zeitlin, Jonathan Frogel, Ilya Lambrikov, Ilia Matskovski, Sumit Chatterji, Lior Seluk, Nadav Furie, Inbal Shafran, Ronen Mass, Amir Onn, Ehud Raanani, Amir Grinberg, Yuval Levy, Arnon Afek, Yitshak Kreiss, Alexander Kogan
Summary: Severe respiratory failure caused by COVID-19 often requires mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Lung transplantation (LTx) may be considered as a last resort, but the patient selection and timing for referral and listing remain uncertain. A retrospective study analyzed severe COVID-19 patients supported by veno-venous ECMO and listed for LTx. Out of 20 patients, 16 were compared, including nine who recovered and seven who died while awaiting LTx. Younger age was significantly associated with a higher likelihood of recovery without LTx after a median of 59 days on ECMO. Referral to LTx should be delayed for 8-10 weeks after ECMO initiation, especially for younger patients with a higher probability of spontaneous recovery.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Virology
Rui-kun Zhang, Qi Xiao, Sheng-lang Zhu, Hai-yan Lin, Ming Tang
Summary: Using 38 blood test indicators, different machine learning models can effectively classify COVID-19 patients into mild and severe cases, with the naive Bayes model showing the best performance.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Immunology
Enric Monreal, Susana Sainz de la Maza, Jose Ignacio Fernandez-Velasco, Elena Natera-Villalba, Claudia Geraldine Rita, Fernando Rodriguez-Jorge, Alvaro Beltran-Corbellini, Ignacio Iturrieta-Zuazo, Enrique Rodriguez de Santiago, Mercedes Espino, Ana de Andres, Jesus Fortun, Esther Barbero, Monica Vazquez, Milagros Fernandez Lucas, Luis Manzano, Beatriz Montero-Errasquin, Lucienne Costa-Frossard, Jaime Masjuan, Luisa Maria Villar
Summary: Research revealed that COVID-19 hospitalized patients receiving immunosuppressive treatment for autoimmune diseases had a lower risk of developing severe ARDS, while those receiving immunosuppressive treatment without autoimmune diseases may have a higher mortality rate.
JOURNAL OF CLINICAL IMMUNOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maurizio Balbi, Caterina Conti, Gianluca Imeri, Anna Caroli, Alessandra Surace, Andrea Corsi, Elisa Mercanzin, Alberto Arrigoni, Giulia Villa, Fabiano Di Marco, Pietro Andrea Bonaffini, Sandro Sironi
Summary: This study evaluated chest CT and PFT findings in severe COVID-19 patients after discharge, revealing that most survivors still had abnormal CT results about three months post-disease onset, with compromised lung volume correlated with PFT results. A small proportion of patients showed impaired diffusion capacity, possibly indicating pulmonary vasculopathy.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Editorial Material
Respiratory System
Sadiyah Sheikh, Fergus W. Hamilton, George W. Nava, Florence K. A. Gregson, David T. Arnold, Colleen Riley, Jules Brown, Jonathan P. Reid, Bryan R. Bzdek, Nicholas A. Maskell, James William Dodd
Summary: Pulmonary function tests are essential for diagnosing respiratory diseases, but the production of potentially infectious aerosols during testing has been a concern. This study found that coughing generated the highest aerosol emission, while the use of viral filters and masks significantly reduced aerosol emission. Mitigation strategies such as these could help reduce the risk of transmission to staff during lung function testing.
Article
Physics, Multidisciplinary
Paolo Castiglioni, Giampiero Merati, Gianfranco Parati, Andrea Faini
Summary: This study aims to compare different entropy measures (DistEn, SampEn, and FuzzyEn) for assessing heart rate variability (HRV). The results show that DistEn mainly reflects cardiovascular complexity, while SampEn and FuzzyEn primarily measure HRV randomness. These methods also exhibit different performance in analyzing postural changes and spinal cord injuries.
Review
Cardiac & Cardiovascular Systems
Luis M. Ruilope, Alberto Ortiz, Alejandro Lucia, Blanca Miranda, Gloria Alvarez-Llamas, Maria G. Barderas, Massimo Volpe, Gema Ruiz-Hurtado, Bertram Pitt
Summary: Chronic kidney disease (CKD) is a leading cause of death that requires early detection for effective management. The current diagnostic criteria for CKD only identify advanced stages, leaving a 'blind spot' in detection where kidney injury is present but undetectable. Elevated urinary albumin-excretion rate can predict future cardiovascular events. Implementing opportunistic or systematic albuminuria screening and therapy has the potential to improve cardiorenal outcomes and mitigate the projected burden of CKD and cardiovascular diseases in the future.
EUROPEAN HEART JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Lucas Lauder, Felix Mahfoud, Michel Azizi, Deepak L. Bhatt, Sebastian Ewen, Kazuomi Kario, Gianfranco Parati, Patrick Rossignol, Markus P. Schlaich, Koon K. Teo, Raymond R. Townsend, Costas Tsioufis, Michael A. Weber, Thomas Weber, Michael Boehm
Summary: Arterial hypertension is a leading cause of death worldwide, with increasing incidence due to aging, obesity, socioeconomic and environmental changes. Lifestyle modifications and antihypertensive drugs are recommended for lowering blood pressure and reducing cardiovascular morbidity and mortality. New drugs and treatments improve cardiovascular and renal outcomes. Comorbidities often complicate management of hypertension.
EUROPEAN HEART JOURNAL
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Rocco Vergallo, Massimo Volpe
EUROPEAN HEART JOURNAL
(2023)
Correction
Cardiac & Cardiovascular Systems
Giuseppe Mascia, Lia Crotti, Antonella Groppelli, Marco Canepa, Andrea Carlo Merlo, Stefano Benenati, Paolo Di Donna, Roberta Della Bona, Davide Soranna, Antonella Zambon, Italo Porto, Iacopo Olivotto, Gianfranco Parati, Michele Brignole, Franco Cecchi
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Review
Oncology
Marta Masini, Matteo Toma, Paolo Spallarossa, Italo Porto, Pietro Ameri
Summary: RCTs have demonstrated that rivaroxaban, edoxaban, and apixaban are equally effective as LMWH in treating CAT, but increase the risk of major gastrointestinal bleeding. Apixaban and rivaroxaban can also prevent CAT in high-risk chemotherapy patients, but may lead to higher bleeding likelihood. Limited data is available for using DOAC in individuals with intracranial tumors or thrombocytopenia, and drug interactions with anticancer agents may affect DOAC effectiveness-safety profile. Current guidelines recommend DOAC as the first-line anticoagulants for CAT, but caution should be exercised in specific patient subgroups.
CURRENT ONCOLOGY REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Edoardo Bertero, Giulia Fracasso, Virginia Eustachi, Domenico Coviello, Massimiliano Cecconi, Stefano Giovinazzo, Matteo Toma, Marco Merlo, Gianfranco Sinagra, Italo Porto, Pietro Ameri, Marco Canepa
Summary: This study aims to assess the diagnostic yield of genetic testing and the relationship between left ventricular reverse remodelling (LVRR) and DNA pathogenic or likely pathogenic variants in patients with dilated cardiomyopathy (DCM). The results showed a diagnostic yield of 24% for genetic testing, and patients without genetic variants had a better LVRR response to guideline-directed medical therapy.
Editorial Material
Cardiac & Cardiovascular Systems
Antonio Salsano, Matilde Bertramino, Luisiana Pastorino, Italo Porto, Francesco Santini
EUROPEAN HEART JOURNAL-CASE REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Arto J. Hautala, Babooshka Shavazipour, Bekir Afsar, Mikko P. Tulppo, Kaisa Miettinen
Summary: This study evaluated the applicability of machine learning tools for predicting healthcare costs in patients with acute coronary syndrome based on known risk markers, and found that depression score is the most significant predictor of healthcare costs.
CARDIOVASCULAR DIGITAL HEALTH JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Mattia Galli, Giovanni M. Vescovo, Felicita Andreotti, Domenico D'amario, Antonio M. Leone, Stefano Benenati, Rocco Vergallo, Giampaolo Niccoli, Carlo Trani, Italo Porto
Summary: In patients with chronic coronary syndromes, the addition of percutaneous coronary intervention (PCI) to optimal medical therapy (OMT) only reduces hard composite outcomes after excluding periprocedural myocardial infarctions (MIs), according to a meta-analysis of randomized controlled trials.
MINERVA CARDIOLOGY AND ANGIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Alessandro Sticchi, Francesco Costa, Saverio Muscoli, Filippo Zilio, Andrea Buono, Rossella Ruggiero, Alessandra Scoccia, Alessandro Caracciolo, Roberto Licordari, Valeria Cammalleri, Fortunato Iacovelli, Marco Loffi, Domenico Scordino, Jayme Ferro, Andrea Rognoni, Stefano Nava, Stefano Albani, Marco Pavani, Iginio Colaiori, Stefano Benenati, Fabio Pescetelli, Vincenzo DE Marzo, Marco Borghesi, Valentina Regazzoni, Antonia Mannarini, Francesco Spione, Baldassarre Doronzo, Michele de Benedictis, Roberto Bonmassari, Gian B. Danzi, Mario Galli, Alfonso Ielasi, Giuseppe Musumeci, Fabrizio Tomai, Antonio Micari, Vincenzo Pasceri, Giuseppe Patti, Italo Porto, Gianluca Campo, Antonio Colombo, Francesco Giannini
Summary: This study aimed to compare predictors of symptoms-to-emergency-call timing delay in acute coronary syndrome (ACS) and their impact on mortality before and during the COVID-19 outbreak. The study found that unstable angina, typical and atypical symptoms, and intermittent angina were significant predictors of symptoms-to-emergency-call timing delay. Contrary to the period before COVID-19, hypertension and dyspnea were not predictors of delay during the pandemic. Furthermore, family attendance at ACS onset was found to reduce symptoms-to-emergency-call timing and mortality.
MINERVA CARDIOLOGY AND ANGIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Gennaro Sardella, Giulio Stefanini, Pier Pasquale Leone, Giacomo Boccuzzi, Natalia Tovar Fovero, Nicolas Van Mieghem, Giuseppe Giacchi, Javier Escaned, Massimo Fineschi, Luca Testa, Renato Valenti, Carlo Di Mario, Carlo Briguori, Bernardo Cortese, Flavio Ribichini, Jacopo Andrea Oreglia, Antonio Colombo, Giuseppe Sangiorgi, Emanuele Barbato, Jeroen Sonck, Fabrizio Ugo, Carlo Trani, Fausto Castriota, Anita Paggi, Italo Porto, Fabrizio Tomai, Massimo Mancone
Summary: This study evaluated the efficacy and safety of IVL with the Shockwave Coronary Rx Lithotripsy System as an elective or bail-out strategy in lesions with severe CAC after RA. The results showed that IVL was effective and safe in treating severe CAC lesions.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Physiology
Kalle Pikkarainen, Rasmus I. P. Valtonen, Heidi E. Hintsala, Antti Kiviniemi, Craig G. Crandall, Juha Perkiomaki, Arto J. Hautala, Mikko P. Tulppo, Jouni J. K. Jaakkola, Tiina M. Ikaheimo
Summary: A cold environment has different effects on post-exercise cardiovascular and autonomic responses. Static upper-body exercise increases post-exercise BRS and overall vagal activity, while dynamic upper-body exercise reduces vagal BRS.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Medicine, General & Internal
Luca Barca, Giuseppe Mascia, Paolo Di Donna, Paolo Sartori, Daniele Bianco, Roberta Della Bona, Stefano Benenati, Andrea Carlo Merlo, Antonia Luisa Buongiorno, Niki Kaufman, Antonio Vena, Matteo Bassetti, Italo Porto
Summary: Transvenous lead extraction (TLE) is the gold standard for the treatment of cardiac implantable electronic devices (CIEDs)-related infection and lead malfunction. However, there is limited data on post-procedural and long-term mortality, particularly in the aging population. This study found that age, atrial fibrillation, and anemia are predictors of mortality in aging patients undergoing TLE.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Edelvita Fernanda Duarte Cunha, Matheus Sobral Silveira, Juliana Cristina Milan-Mattos, Heitor Fernandes Silveira Cavalini, Adrya Aryelle Ferreira, Joice de Souza Batista, Lara Caze Uzumaki, Joao Paulo Coelho Guimaraes, Pedro Igor Lustosa Roriz, Fabianne Maisa de Novaes Assis Dantas, Arto J. Hautala, Raphael Martins de Abreu, Aparecida Maria Catai, Paulo Adriano Schwingel, Victor Ribeiro Neves
Summary: This study assessed the impact of COVID-19 on cardiac autonomic function and functional capacity in individuals with systemic arterial hypertension (SAH). The results showed that SAH individuals post-COVID-19 had shorter walking distances in the 6-minute walk test (6MWT), but there was no impaired cardiac autonomic function compared to SAH individuals without COVID-19.
JOURNAL OF PERSONALIZED MEDICINE
(2023)