Milk thistle (Silybum marianum ): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Milk thistle (Silybum marianum
): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases
Authors
Keywords
-
Journal
PHYTOTHERAPY RESEARCH
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-08-07
DOI
10.1002/ptr.6171
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Relative Bioavailability of Silybin A and Silybin B From 2 Multiconstituent Dietary Supplement Formulations Containing Milk Thistle Extract: A Single-dose Study
- (2018) Wen-Yi Li et al. CLINICAL THERAPEUTICS
- Silybin inhibits NLRP3 inflammasome assembly through the NAD+/SIRT2 pathway in mice with nonalcoholic fatty liver disease
- (2018) Bangling Zhang et al. FASEB JOURNAL
- Global epidemiology of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: What we need in the future
- (2018) Ana Ruth Araújo et al. LIVER INTERNATIONAL
- The silymarin composition… and why does it matter???
- (2017) Christopher Steven Chambers et al. FOOD RESEARCH INTERNATIONAL
- Silymarin impacts on immune system as an immunomodulator: One key for many locks
- (2017) Nafiseh Esmaeil et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- High Dose of Silymarin in Patients with Decompensated Liver Disease: A Randomized Controlled Trial
- (2017) Waleed Fouad Fathalah et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease
- (2017) Sheng Zhong et al. MEDICINE
- Silybin, a Major Bioactive Component of Milk Thistle (Silybum marianum L. Gaernt.)—Chemistry, Bioavailability, and Metabolism
- (2017) Michal Bijak MOLECULES
- Iron-chelating effect of silymarin in patients with β-thalassemia major: A crossover randomised control trial
- (2017) Hadi Darvishi-Khezri et al. PHYTOTHERAPY RESEARCH
- Traditional Oriental Herbal Medicine and Natural Killer Cells for Cancer Patients: A Systematic Review and Meta-analysis
- (2017) Kyeore Bae et al. PHYTOTHERAPY RESEARCH
- A systematic review on ethnomedicines of anti-cancer plants
- (2017) Akash Tariq et al. PHYTOTHERAPY RESEARCH
- Effects of Silymarin on Diabetes Mellitus Complications: A Review
- (2017) Aline Maria Stolf et al. PHYTOTHERAPY RESEARCH
- Spatial organization of silybin biosynthesis in milk thistle [Silybum marianum (L.) Gaertn]
- (2017) Yongkun Lv et al. PLANT JOURNAL
- Treatment with milk thistle extract (Silybum marianum), ursodeoxycholic acid, or their combination attenuates cholestatic liver injury in rats: Role of the hepatic stem cells
- (2017) Nuray Alaca et al. Turkish Journal of Gastroenterology
- Effect of silymarin on biochemical indicators in patients with liver disease: Systematic review with meta-analysis
- (2017) Camila Ribeiro de Avelar et al. WORLD JOURNAL OF GASTROENTEROLOGY
- From diagnosis to treatment of hepatocellular carcinoma: An epidemic problem for both developed and developing world
- (2017) Dimitrios Dimitroulis et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Effects of Oral Administration of Silymarin in a Juvenile Murine Model of Non-alcoholic Steatohepatitis
- (2017) Veronica Marin et al. Nutrients
- Effect of Mediterranean Diet and Antioxidant Formulation in Non-Alcoholic Fatty Liver Disease: A Randomized Study
- (2017) Ludovico Abenavoli et al. Nutrients
- Silymarin-loaded Eudragit ® RS100 nanoparticles improved the ability of silymarin to resolve hepatic fibrosis in bile duct ligated rats
- (2016) N. Younis et al. BIOMEDICINE & PHARMACOTHERAPY
- Zidovudine and isoniazid induced liver toxicity and oxidative stress: Evaluation of mitigating properties of silibinin
- (2016) Ramanathan Raghu et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer – A comprehensive review
- (2016) Navaneethakrishnan Polachi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Highly bioavailable silibinin nanoparticles inhibit HCV infection
- (2016) Ching-Hsuan Liu et al. GUT
- Dietary supplementation in patients with alcoholic liver disease: a review on current evidence
- (2016) Zeinab Ghorbani et al. Hepatobiliary & Pancreatic Diseases International
- Preventive use of a hepatoprotectant against anti-tuberculosis drug-induced liver injury: A randomized controlled trial
- (2016) Simin Zhang et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Beneficial Effects of Silymarin After the Discontinuation of CCl4-Induced Liver Fibrosis
- (2016) Simona Clichici et al. JOURNAL OF MEDICINAL FOOD
- The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013
- (2016) Jeffrey D Stanaway et al. LANCET
- Acute liver injury and acute liver failure from mushroom poisoning in North America
- (2016) Constantine J. Karvellas et al. LIVER INTERNATIONAL
- Silymarin Prevents Restraint Stress-Induced Acute Liver Injury by Ameliorating Oxidative Stress and Reducing Inflammatory Response
- (2016) Sou Kim et al. MOLECULES
- Variation in the flavonolignan composition of fruits from different Silybum marianum chemotypes and suspension cultures derived therefrom
- (2016) Lennart Poppe et al. PHYTOCHEMISTRY
- Herbal Medicine Offered as an Initiative Therapeutic Option for the Management of Hepatocellular Carcinoma
- (2016) Shao-Ru Chen et al. PHYTOTHERAPY RESEARCH
- Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets
- (2016) Stephen Safe et al. PHYTOTHERAPY RESEARCH
- Metabolic aspects of adult patients with nonalcoholic fatty liver disease
- (2016) Ludovico Abenavoli et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Silibinin: a potential old drug for cancer therapy
- (2016) Xing-Xing Zhu et al. Expert Review of Clinical Pharmacology
- Silymarin and hepatocellular carcinoma
- (2015) Jeanetta K. Mastron et al. ANTI-CANCER DRUGS
- A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury
- (2015) Chote Luangchosiri et al. BMC Complementary and Alternative Medicine
- Evaluating the Safety and Efficacy of Silymarin inβ-Thalassemia Patients: A Review
- (2015) Behjat Al-Sadat Moayedi Esfahani et al. HEMOGLOBIN
- Hepatic inflammation and fibrosis: Functional links and key pathways
- (2015) Ekihiro Seki et al. HEPATOLOGY
- Enhanced oral bioavailability of silymarin using liposomes containing a bile salt: preparation by supercritical fluid technology and evaluation in vitro and in vivo
- (2015) Gang Yang et al. International Journal of Nanomedicine
- Silymarin Inhibits the Progression of Fibrosis in the Early Stages of Liver Injury in CCl4-Treated Rats
- (2015) Simona Clichici et al. JOURNAL OF MEDICINAL FOOD
- Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway
- (2015) Eun Jeong Kim et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Natural antioxidants for non-alcoholic fatty liver disease: molecular targets and clinical perspectives
- (2015) Federico Salomone et al. LIVER INTERNATIONAL
- Effects of Mediterranean diet supplemented with silybin–vitamin E–phospholipid complex in overweight patients with non-alcoholic fatty liver disease
- (2015) Ludovico Abenavoli et al. Expert Review of Gastroenterology & Hepatology
- Silybin exerts antioxidant effects and induces mitochondrial biogenesis in liver of rat with secondary biliary cirrhosis
- (2014) Gaetano Serviddio et al. FREE RADICAL BIOLOGY AND MEDICINE
- Chemistry of silybin
- (2014) D. Biedermann et al. NATURAL PRODUCT REPORTS
- Serum Oxidative Stress Markers and Lipidomic Profile to Detect NASH Patients Responsive to an Antioxidant Treatment: A Pilot Study
- (2014) Paola Stiuso et al. Oxidative Medicine and Cellular Longevity
- In Vivo Efficacy Study of Milk Thistle Extract (ETHIS-094™) in STAM™ Model of Nonalcoholic Steatohepatitis
- (2014) Pilar Pais et al. Drugs in research & development
- Effects and Tolerance of Silymarin (Milk Thistle) in Chronic Hepatitis C Virus Infection Patients: A Meta-Analysis of Randomized Controlled Trials
- (2014) Zongguo Yang et al. Biomed Research International
- Immunosuppressive Effect of Silymarin on Mitogen-Activated Protein Kinase Signalling Pathway: the Impact on T Cell Proliferation and Cytokine Production
- (2013) Marjan Gharagozloo et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- A Phase I Dose-Finding Study of Silybin Phosphatidylcholine (Milk Thistle) in Patients With Advanced Hepatocellular Carcinoma
- (2013) Abby B. Siegel et al. INTEGRATIVE CANCER THERAPIES
- Milk thistle: early seeds of potential
- (2013) Abby B Siegel et al. LANCET ONCOLOGY
- Inhibition of HIV by Legalon-SIL is independent of its effect on cellular metabolism
- (2013) Janela McClure et al. VIROLOGY
- Milk thistle to treat non-alcoholic fatty liver disease: dream or reality?
- (2013) Ludovico Abenavoli et al. Expert Review of Gastroenterology & Hepatology
- Legalon® SIL: The Antidote of Choice in Patients with Acute Hepatotoxicity from Amatoxin Poisoning
- (2012) Ulrich Mengs et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Meta-analysis: silymarin and its combination therapy for the treatment of chronic hepatitis B
- (2012) F. Wei et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Identification of novel mechanisms of silymarin on the carbon tetrachloride-induced liver fibrosis in mice by nuclear factor-κB bioluminescent imaging-guided transcriptomic analysis
- (2012) Chia-Cheng Li et al. FOOD AND CHEMICAL TOXICOLOGY
- Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: A randomized controlled trial
- (2012) Carmela Loguercio et al. FREE RADICAL BIOLOGY AND MEDICINE
- Silymarin suppresses hepatic stellate cell activation in a dietary rat model of non-alcoholic steatohepatitis: Analysis of isolated hepatic stellate cells
- (2012) MINA KIM et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Effect of Silymarin (Milk Thistle) on Liver Disease in Patients With Chronic Hepatitis C Unsuccessfully Treated With Interferon Therapy
- (2012) Michael W. Fried JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Interactions between Herbs and Conventional Drugs: Overview of the Clinical Data
- (2012) Angelo A. Izzo MEDICAL PRINCIPLES AND PRACTICE
- Absorption and metabolism of milk thistle flavanolignans in humans
- (2012) Luca Calani et al. PHYTOMEDICINE
- Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
- (2011) S. J. Schrieber et al. DRUG METABOLISM AND DISPOSITION
- Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases
- (2011) Petra Jančová et al. XENOBIOTICA
- Anti-apoptotic and anti-inflammatory effects of Silybum marianum in treatment of experimental steatohepatitis
- (2010) Safiyeh Aghazadeh et al. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
- Milk thistle in liver diseases: past, present, future
- (2010) Ludovico Abenavoli et al. PHYTOTHERAPY RESEARCH
- Silymarin Ascending Multiple Oral Dosing Phase I Study in Noncirrhotic Patients With Chronic Hepatitis C
- (2009) Roy L. Hawke et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Solid State Mechanochemical Activation of Silybum marianum Dry Extract With Betacyclodextrins: Characterization and Bioavailability of the Coground Systems
- (2009) D. Voinovich et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- The Pharmacokinetics of Silymarin Is Altered in Patients with Hepatitis C Virus and Nonalcoholic Fatty Liver Disease and Correlates with Plasma Caspase-3/7 Activity
- (2008) S. J. Schrieber et al. DRUG METABOLISM AND DISPOSITION
- Drug–drug interactions of silymarin on the perspective of pharmacokinetics
- (2008) Jhy-Wen Wu et al. JOURNAL OF ETHNOPHARMACOLOGY
- An Updated Systematic Review with Meta-Analysis for the Clinical Evidence of Silymarin
- (2008) R. Saller et al. FORSCHENDE KOMPLEMENTARMEDIZIN
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now