Genetic risk factors for drug-induced liver injury in rheumatoid arthritis patients using low-dose methotrexate

Using Genome-Wide Association Studies to Identify Genes Important in Serious Adverse Drug Reactions

(2011) Ann K. Daly   Annual Review of Pharmacology and Toxicology

Comparison of Effect Sizes Associated With Biomarkers Reported in Highly Cited Individual Articles and in Subsequent Meta-analyses

(2011) John P. A. Ioannidis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PharmGKB summary

(2011) Torben S. Mikkelsen et al.   Pharmacogenetics and Genomics

Methylene tetrahydrofolate reductase gene polymorphisms and their association with methotrexate toxicity

(2011) Kalliopi P. Spyridopoulou et al.   Pharmacogenetics and Genomics

The C677T polymorphism in theMTHFRgene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population

(2011) R Cáliz et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Gastrointestinal and liver side effects of drugs in elderly patients

(2010) Konstantinos Triantafyllou et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Gastrointestinal and liver adverse effects of drugs used for treating IBD

(2010) Gerhard Rogler   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Associations between the C677T and A1298C Polymorphisms of MTHFR and the Efficacy and Toxicity of Methotrexate in Rheumatoid Arthritis

(2010) Young Ho Lee et al.   CLINICAL DRUG INVESTIGATION

Pharmacogenomics in Drug Induced Liver Injury

(2010) Raul Andrade et al.   CURRENT DRUG METABOLISM

Ongoing Challenges in Drug Interaction Safety: from Exposure to Pharmacogenomics

(2010) Jane P.F. Bai   Drug Metabolism and Pharmacokinetics

Pharmacogenetics of drug-induced liver injury

(2010) Stefan Russmann et al.   HEPATOLOGY

Standardization of nomenclature and causality assessment in drug-induced liver injury: Summary of a clinical research workshop

(2010) Robert J. Fontana et al.   HEPATOLOGY

Genome-wide association studies in pharmacogenomics

(2010) Ann K. Daly   NATURE REVIEWS GENETICS

Methotrexate—how does it really work?

(2010) Edwin S. L. Chan et al.   Nature Reviews Rheumatology

Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis

(2010) Wouter M Kooloos et al.   PHARMACOGENOMICS

Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases

(2010) J P Mena et al.   PHARMACOGENOMICS JOURNAL

Rare incidence of methotrexate-specific lesions in liver biopsy of patients with arthritis and elevated liver enzymes

(2010) Emilie Quintin et al.   ARTHRITIS RESEARCH & THERAPY

Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide

(2009) J R Curtis et al.   ANNALS OF THE RHEUMATIC DISEASES

Pharmacogenetics in Treatment of Rheumatoid Arthritis

(2009) W. Kooloos et al.   CURRENT PHARMACEUTICAL DESIGN

Metaanalysis of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms Affecting Methotrexate Toxicity

(2009) M. C. FISHER et al.   JOURNAL OF RHEUMATOLOGY

Gene–gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis

(2009) Thierry Dervieux et al.   Pharmacogenetics and Genomics

Hepatotoxicity rates do not differ in patients with rheumatoid arthritis and psoriasis treated with methotrexate

(2009) H. Amital et al.   RHEUMATOLOGY

Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative

(2008) K Visser et al.   ANNALS OF THE RHEUMATIC DISEASES

Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX

(2008) S. L. Hider et al.   RHEUMATOLOGY