The utility of yeast as a tool for cell-based, target-directed high-throughput screening

Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

(2013) E. Bilsland et al.   Open Biology

Identification of Biologically Active PDE11-Selective Inhibitors Using a Yeast-Based High-Throughput Screen

(2012) Ozge Ceyhan et al.   CHEMISTRY & BIOLOGY

Understanding and creating value from open source drug discovery for neglected tropical diseases

(2012) Minna Allarakhia et al.   Expert Opinion on Drug Discovery

An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages

(2012) Jair L. Siqueira-Neto et al.   PLoS Neglected Tropical Diseases

Functional genetics in Apicomplexa: Potentials and limits

(2011) Julien Limenitakis et al.   FEBS LETTERS

Phosphodiesterase inhibitors as a new generation of antiprotozoan drugs: exploiting the benefit of enzymes that are highly conserved between host and parasite

(2011) Thomas Seebeck et al.   Future Medicinal Chemistry

Exploring Leishmania major Inositol Phosphorylceramide Synthase (LmjIPCS): Insights into the ceramide binding domain

(2011) John G. Mina et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A yeast-based assay identifies drugs active against human mitochondrial disorders

(2011) E. Couplan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Expression of Parasite Drug Targets and Their Human Orthologs in Yeast

(2011) Elizabeth Bilsland et al.   PLoS Neglected Tropical Diseases

Recent Progress in Phosphoinositide 3-Kinases: Oncogenic Properties and Prognostic and Therapeutic Implications

(2010) Guojun Wu   CURRENT PROTEIN & PEPTIDE SCIENCE

Targeting kinases for the treatment of inflammatory diseases

(2010) Susanne Müller et al.   Expert Opinion on Drug Discovery

A plate-based assay system for analyses and screening of the Leishmania major inositol phosphorylceramide synthase

(2010) John G. Mina et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cell-Based Assays for High-Throughput Screening

(2010) W. Frank An et al.   MOLECULAR BIOTECHNOLOGY

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

Recombinant yeast screen for new inhibitors of human acetyl-CoA carboxylase 2 identifies potential drugs to treat obesity

(2010) J. Marjanovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Antimalarial Drug Quinine Disrupts Tat2p-mediated Tryptophan Transport and Causes Tryptophan Starvation

(2009) Combiz Khozoie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target

(2009) John G. Mina et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Identification of Human Intracellular Targets of the Medicinal Herb St. John’s Wort by Chemical−Genetic Profiling in Yeast

(2008) Patrick P. McCue et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY