Phosphodiesterase inhibitors as a new generation of antiprotozoan drugs: exploiting the benefit of enzymes that are highly conserved between host and parasite

Kinetoplastida: new therapeutic strategies

(2013) S.L. Croft   Parasite

Factors of occurrence of ocular toxoplasmosis. A review

(2013) H. Talabani et al.   Parasite

State of the Art in African Trypanosome Drug Discovery

(2011) Robert T. Jacobs et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Studies of quinapyramine-resistance of Trypanosoma brucei evansi in China

(2010) Dangjin Liao et al.   ACTA TROPICA

Socio–economic aspects of neglected diseases: sleeping sickness and visceral leishmaniasis

(2010) M. Boelaert et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

(2010) B. Nare et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chemical Validation of Phosphodiesterase C as a Chemotherapeutic Target in Trypanosoma cruzi, the Etiological Agent of Chagas' Disease

(2010) S. King-Keller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The emerging of the fifth malaria parasite (Plasmodium knowlesi): a public health concern?

(2010) Sergio Sabbatani et al.   Brazilian Journal of Infectious Diseases

Cutaneous leishmaniasis: advances in disease pathogenesis, diagnostics and therapeutics

(2010) M. Ameen   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Importance of Nonenteric Protozoan Infections in Immunocompromised People

(2010) J. L. N. Barratt et al.   CLINICAL MICROBIOLOGY REVIEWS

New antileishmanial candidates and lead compounds

(2010) Julian V Richard et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Accelerating drug development and approval

(2010) P. Cole   DRUG NEWS & PERSPECTIVES

The N Terminus of Phosphodiesterase TbrPDEB1 of Trypanosoma brucei Contains the Signal for Integration into the Flagellar Skeleton

(2010) Edith Luginbuehl et al.   EUKARYOTIC CELL

Host immune response to Cryptosporidium parvum infection

(2010) Franz Petry et al.   EXPERIMENTAL PARASITOLOGY

Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis

(2010) Hiro Goto et al.   Expert Review of Anti-Infective Therapy

Emerging and Established Parasitic Lung Infestations

(2010) Vannan Kandi Vijayan et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Giardia taxonomy, phylogeny and epidemiology: Facts and open questions

(2010) Judit Plutzer et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Shrinking the malaria map: progress and prospects

(2010) Richard GA Feachem et al.   LANCET

Chagas disease: changes in knowledge and management

(2010) François-Xavier Lescure et al.   LANCET INFECTIOUS DISEASES

Treating ocular toxoplasmosis: current evidence

(2010) MR Stanford et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Ocular toxoplasmosis: an update and review of the literature

(2010) Alessandra G Commodaro et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi

(2010) Alejandra C. Schoijet et al.   MOLECULAR MICROBIOLOGY

Neglected diseases fund touted

(2010) Declan Butler   NATURE

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

Erratum: Artemisinin resistance: current status and scenarios for containment

(2010) Arjen M. Dondorp et al.   NATURE REVIEWS MICROBIOLOGY

The Selection Landscape of Malaria Parasites

(2010) M. J. Mackinnon et al.   SCIENCE

Following the path of most resistance: dhps K540E dispersal in African Plasmodium falciparum

(2010) Inbarani Naidoo et al.   TRENDS IN PARASITOLOGY

Current and developing therapeutic agents in the treatment of Chagas disease

(2010) Werner Apt   Drug Design Development and Therapy

NECT Is Next: Implementing the New Drug Combination Therapy for Trypanosoma brucei gambiense Sleeping Sickness

(2010) Oliver Yun et al.   PLoS Neglected Tropical Diseases

Diamidine Activity Against Trypanosomes: The State of the Art

(2010) M. Soeiro et al.   Current Molecular Pharmacology

New Treatment Option for Second-Stage African Sleeping Sickness: In Vitro and In Vivo Efficacy of Aza Analogs of DB289

(2009) T. Wenzler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Significance of Enteric Protozoa in the Immunosuppressed Human Population

(2009) D. Stark et al.   CLINICAL MICROBIOLOGY REVIEWS

Cutaneous and mucocutaneous leishmaniasis

(2009) Consuelo V. David et al.   Dermatologic Therapy

Leishmania major: Effect of protein kinase A and phosphodiesterase activity on infectivity and proliferation of promastigotes

(2009) Laura Malki-Feldman et al.   EXPERIMENTAL PARASITOLOGY

Reassessment of the epidemiology of amebiasis: State of the art

(2009) Cecilia Ximénez et al.   INFECTION GENETICS AND EVOLUTION

Human African trypanosomiasis

(2009) Reto Brun et al.   LANCET

Genetics and visceral leishmaniasis: of mice and man

(2009) J. M. BLACKWELL et al.   PARASITE IMMUNOLOGY

A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite

(2009) Robert W. Moon et al.   PLoS Pathogens

Clinical Practice: Management ofToxoplasma gondiiInfection during Pregnancy

(2008) Jose G. Montoya et al.   CLINICAL INFECTIOUS DISEASES

Large differences in the genome organization of different plant Trypanosomatid parasites (Phytomonas spp.) reveal wide evolutionary divergences between taxa

(2008) C. Marín et al.   INFECTION GENETICS AND EVOLUTION

Cyclic nucleotide-specific phosphodiesterases of Plasmodium falciparum: PfPDEα, a non-essential cGMP-specific PDE that is an integral membrane protein

(2008) Laurent Wentzinger et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Trichomonas vaginalisInfection and Human Immunodeficiency Virus Acquisition in African Women

(2008) Barbara Van Der Pol et al.   JOURNAL OF INFECTIOUS DISEASES

Disruption of aPlasmodium falciparumcyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis

(2008) Cathy J. Taylor et al.   MOLECULAR MICROBIOLOGY

FDA launches priority vouchers for neglected-disease drugs

(2008) Emily Waltz   NATURE BIOTECHNOLOGY

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

(2008) Harald Noedl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Leishmaniasis treatment—a challenge that remains: a review

(2008) Dilvani O. Santos et al.   PARASITOLOGY RESEARCH

Ever-increasing complexities of diamidine and arsenical crossresistance in African trypanosomes

(2008) Harry P. de Koning   TRENDS IN PARASITOLOGY

Plasmodium knowlesi Malaria in Humans Is Widely Distributed and Potentially Life Threatening

(2007) J. Cox-Singh et al.   CLINICAL INFECTIOUS DISEASES

Plasmodium knowlesi: The Fifth Human Malaria Parasite

(2007) N. J. White   CLINICAL INFECTIOUS DISEASES