A Randomized Study of Lubiprostone for Opioid-Induced Constipation in Patients with Chronic Noncancer Pain

Analgesia during long-term lubiprostone therapy in patients with opioid-induced constipation and chronic, non-cancer pain: results from a phase 3, open-label clinical trial

(2013) T. Joswick et al.   JOURNAL OF PAIN

Prevalence and comorbidity of chronic pain in the German general population

(2012) Maurice M. Ohayon et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Opioid-Induced Constipation: Challenges and Therapeutic Opportunities

(2011) Michael Camilleri   AMERICAN JOURNAL OF GASTROENTEROLOGY

A Randomized, Placebo-Controlled Phase 3 Trial (Study SB-767905/012) of Alvimopan for Opioid-Induced Bowel Dysfunction in Patients With Non-Cancer Pain

(2011) Jan-Peter Jansen et al.   JOURNAL OF PAIN

A Randomized, Placebo-Controlled Phase 3 Trial (Study SB-767905/013) of Alvimopan for Opioid-Induced Bowel Dysfunction in Patients With Non-Cancer Pain

(2011) Gordon Irving et al.   JOURNAL OF PAIN

Prevalence and Characteristics of Chronic Pain Among Long-term Social Assistance Recipients Compared to the General Population in Norway

(2010) Borghild Løyland et al.   CLINICAL JOURNAL OF PAIN

The Prevalence of Chronic Pain in United States Adults: Results of an Internet-Based Survey

(2010) Catherine B. Johannes et al.   JOURNAL OF PAIN

Efficacy and Safety of Lubiprostone in Patients with Chronic Constipation

(2009) Charles F. Barish et al.   DIGESTIVE DISEASES AND SCIENCES

Long-Acting Opioids and Short-Acting Opioids: Appropriate Use in Chronic Pain Management

(2009) Perry G. Fine et al.   PAIN MEDICINE

Opioid receptors in the gastrointestinal tract

(2009) Peter Holzer   REGULATORY PEPTIDES

Alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist for the treatment of opioid-induced bowel dysfunction: Results from a randomized, double-blind, placebo-controlled, dose-finding study in subjects taking opioids for chronic non-cancer pain

(2008) Lynn Webster et al.   PAIN

The Prevalence, Severity, and Impact of Opioid-Induced Bowel Dysfunction: Results of a US and European Patient Survey (PROBE 1)

(2008) Timothy J. Bell et al.   PAIN MEDICINE

Multicenter, 4-Week, Double-Blind, Randomized, Placebo-Controlled Trial of Lubiprostone, a Locally-Acting Type-2 Chloride Channel Activator, in Patients With Chronic Constipation

(2007) John F Johanson et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY