Microtubule C-Terminal Tails Can Change Characteristics of Motor Force Production

Microtubule detyrosination guides chromosomes during mitosis

(2015) M. Barisic et al.   SCIENCE

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation

(2015) Albert Herms et al.   Nature Communications

Kinesin-1 translocation: Surprising differences between bovine brain and MCF7-derived microtubules

(2014) Mitra Shojania Feizabadi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of α-Tubulin K40 Acetylation and Detyrosination on Kinesin-1 Motility in a Purified System

(2014) Neha Kaul et al.   BIOPHYSICAL JOURNAL

Calibration of Optical Tweezers for In Vivo Force Measurements: How do Different Approaches Compare?

(2014) Yonggun Jun et al.   BIOPHYSICAL JOURNAL

The family-specific K-loop influences the microtubule on-rate but not the superprocessivity of kinesin-3 motors

(2014) Virupakshi Soppina et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

(2014) Minhajuddin Sirajuddin et al.   NATURE CELL BIOLOGY

CK2 activates kinesin via induction of a conformational change

(2014) M. K. Mattson-Hoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family

(2014) Adeline Goulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells

(2013) Arpan K. Rai et al.   CELL

“Snapshots” of Ispinesib-induced Conformational Changes in the Mitotic Kinesin Eg5

(2013) Hung Yi Kristal Kaan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Second Tubulin Binding Site on the Kinesin-13 Motor Head Domain Is Important during Mitosis

(2013) Dong Zhang et al.   PLoS One

Measuring Molecular Motor Forces In Vivo: Implications for Tug-of-War Models of Bidirectional Transport

(2012) Christina Leidel et al.   BIOPHYSICAL JOURNAL

The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5

(2012) Adeline Goulet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neck-Linker Length Dependence of Processive Kinesin-5 Motility

(2012) André Düselder et al.   JOURNAL OF MOLECULAR BIOLOGY

Tubulin Acetylation Alone Does Not Affect Kinesin-1 Velocity and Run Length In Vitro

(2012) Wilhelm J. Walter et al.   PLoS One

Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors

(2012) A. G. Hendricks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning Multiple Motor Travel via Single Motor Velocity

(2012) Jing Xu et al.   TRAFFIC

The Loop 5 Element Structurally and Kinetically Coordinates Dimers of the Human Kinesin-5, Eg5

(2011) Joshua S. Waitzman et al.   BIOPHYSICAL JOURNAL

Productive Cooperation among Processive Motors Depends Inversely on Their Mechanochemical Efficiency

(2011) Jonathan W. Driver et al.   BIOPHYSICAL JOURNAL

Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport

(2011) A. Kunwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interhead tension determines processivity across diverse N-terminal kinesins

(2011) S. Shastry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Kinesins Transport Cargo Primarily via the Action of One Motor: Implications for Intracellular Transport

(2010) D. Kenneth Jamison et al.   BIOPHYSICAL JOURNAL

LIS1 and NudE Induce a Persistent Dynein Force-Producing State

(2010) Richard J. McKenney et al.   CELL

The Effect of Monastrol on the Processive Motility of a Dimeric Kinesin-5 Head/Kinesin-1 Stalk Chimera

(2010) Stefan Lakämper et al.   JOURNAL OF MOLECULAR BIOLOGY

Intracellular Transport: How Do Motors Work Together?

(2009) Roop Mallik et al.   CURRENT BIOLOGY

Motor-dependent microtubule disassembly driven by tubulin tyrosination

(2009) Leticia Peris et al.   JOURNAL OF CELL BIOLOGY

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

(2009) Yoshiyuki Konishi et al.   NATURE NEUROSCIENCE

Consequences of Motor Copy Number on the Intracellular Transport of Kinesin-1-Driven Lipid Droplets

(2008) George T. Shubeita et al.   CELL

Stepping, Strain Gating, and an Unexpected Force-Velocity Curve for Multiple-Motor-Based Transport

(2008) Ambarish Kunwar et al.   CURRENT BIOLOGY

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells

(2008) S. Dunn et al.   JOURNAL OF CELL SCIENCE