The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5

All-Atom Structural Investigation of Kinesin–Microtubule Complex Constrained by High-Quality Cryo-Electron-Microscopy Maps

(2012) Minghui Li et al.   BIOCHEMISTRY

Neck-Linker Length Dependence of Processive Kinesin-5 Motility

(2012) André Düselder et al.   JOURNAL OF MOLECULAR BIOLOGY

The Loop 5 Element Structurally and Kinetically Coordinates Dimers of the Human Kinesin-5, Eg5

(2011) Joshua S. Waitzman et al.   BIOPHYSICAL JOURNAL

Role of Insert-1 of Myosin VI in Modulating Nucleotide Affinity

(2011) Olena Pylypenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Finding rigid bodies in protein structures: Application to flexible fitting into cryoEM maps

(2011) Arun Prasad Pandurangan et al.   JOURNAL OF STRUCTURAL BIOLOGY

Analysis of the interaction of the Eg5 Loop5 with the nucleotide site

(2011) Timothy D. Harrington et al.   JOURNAL OF THEORETICAL BIOLOGY

A universal pathway for kinesin stepping

(2011) Bason E Clancy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Conserved L5 Loop Establishes the Pre-Powerstroke Conformation of the Kinesin-5 Motor, Eg5

(2010) Adam G. Larson et al.   BIOPHYSICAL JOURNAL

Neck Linker Length Determines the Degree of Processivity in Kinesin-1 and Kinesin-2 Motors

(2010) Shankar Shastry et al.   CURRENT BIOLOGY

Modulation of the Kinesin ATPase Cycle by Neck Linker Docking and Microtubule Binding

(2010) Yu Cheng Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loop 5-directed Compounds Inhibit Chimeric Kinesin-5 Motors

(2010) Liqiong Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loop L5 Acts as a Conformational Latch in the Mitotic Kinesin Eg5

(2010) William M. Behnke-Parks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Allosteric Drug Discrimination Is Coupled to Mechanochemical Changes in the Kinesin-5 Motor Core

(2010) Elizabeth D. Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An atomic-level mechanism for activation of the kinesin molecular motors

(2010) C. V. Sindelar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitotic functions of kinesin-5

(2010) Nick P. Ferenz et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

An allosteric transition trapped in an intermediate state of a new kinesin–inhibitor complex

(2009) Hung Yi Kristal Kaan et al.   BIOCHEMICAL JOURNAL

Thermodynamics of Nucleotide and Inhibitor Binding to Wild-Type and Ispinesib-Resistant Forms of Human Kinesin Spindle Protein

(2009) Payal R. Sheth et al.   BIOCHEMISTRY

ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism

(2009) Courtney L. Parke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

9-Ångström Structure of a Microtubule-Bound Mitotic Motor

(2009) Andrew J. Bodey et al.   JOURNAL OF MOLECULAR BIOLOGY

Why kinesin is so processive

(2009) E. Toprak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting the Kinesin Spindle Protein: Basic Principles and Clinical Implications

(2008) V. Sarli et al.   CLINICAL CANCER RESEARCH

The Role of Kinesin Neck Linker and Neck in Velocity Regulation

(2008) Nikolina Kalchishkova et al.   JOURNAL OF MOLECULAR BIOLOGY

Kinesin's cover-neck bundle folds forward to generate force

(2008) A. S. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Structure Fitting and Refinement Guided by Cryo-EM Density

(2008) Maya Topf et al.   STRUCTURE

Force Generation in Kinesin Hinges on Cover-Neck Bundle Formation

(2008) Wonmuk Hwang et al.   STRUCTURE

The role of microtubules in processive kinesin movement

(2008) Masahide Kikkawa   TRENDS IN CELL BIOLOGY