γH2AX Assay as DNA Damage Biomarker for Human Population Studies: Defining Experimental Conditions

Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker

(2016) Christophe E. Redon et al.   Aging-US

Gamma histone 2AX (γ-H2AX)as a predictive tool in radiation oncology

(2014) Stamatia Pouliliou et al.   BIOMARKERS

γ-H2AX as a biomarker for DNA double-strand breaks in ecotoxicology

(2014) Marko Gerić et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The γH2AX Assay for Genotoxic and Nongenotoxic Agents: Comparison of H2AX Phosphorylation with Cell Death Response

(2014) Teodora Nikolova et al.   TOXICOLOGICAL SCIENCES

Kinetics of nuclear phosphorylation ( -H2AX) in human lymphocytes treated in vitro with UVB, bleomycin and mitomycin C

(2013) R. Scarpato et al.   MUTAGENESIS

Effect of blood storage conditions on DNA repair capacity measurements in peripheral blood mononuclear cells

(2013) Alessandra Allione et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies

(2013) Vanessa Valdiglesias et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Dose-Response Modeling of Etoposide-Induced DNA Damage Response

(2013) Zhenhong Li et al.   TOXICOLOGICAL SCIENCES

Age and gender effects on DNA strand break repair in peripheral blood mononuclear cells

(2012) Christian Garm et al.   AGING CELL

In vivo versus in vitro individual radiosensitivity analysed in healthy donors and in prostate cancer patients with and without severe side effects after radiotherapy

(2012) Kinga Brzozowska et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles

(2011) Steve Quiros et al.   CELL CYCLE

Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines

(2011) Kimiyo N. Yamamoto et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment

(2011) Emma C. Bourton et al.   INTERNATIONAL JOURNAL OF CANCER

Okadaic acid induces morphological changes, apoptosis and cell cycle alterations in different human cell types

(2011) Vanessa Valdiglesias et al.   JOURNAL OF ENVIRONMENTAL MONITORING

DNA damage response in resting and proliferating peripheral blood lymphocytes treated by camptothecin or X-ray

(2011) Ming Tian et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Evaluation of Okadaic Acid-Induced Genotoxicity in Human Cells Using the Micronucleus Test and γH2AX Analysis

(2011) Vanessa Valdiglesias et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

γH2AX foci as a measure of DNA damage: A computational approach to automatic analysis

(2011) Alesia N. Ivashkevich et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Genotoxicity screening via the γH2AX by flow assay

(2011) D.J. Smart et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

γH2Ax: Biomarker of Damage or Functional Participant in DNA Repair “All that Glitters Is not Gold!”

(2011) James E. Cleaver   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease

(2011) Wenjian Ma et al.   PLoS Genetics

Residual γH2AX foci as an indication of lethal DNA lesions

(2010) Judit P Banáth et al.   BMC CANCER

Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis

(2010) Mary Mohrin et al.   Cell Stem Cell

γH2AX as a molecular marker of aging and disease

(2010) Li-Jeen Mah et al.   Epigenetics

Whole cell-ELISA to measure the γH2AX response of six aneugens and eight DNA-damaging chemicals

(2010) Kaori Matsuzaki et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Role of oxidatively induced DNA lesions in human pathogenesis

(2010) Olga A. Sedelnikova et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Delayed kinetics of DNA double-strand break processing in normal and pathological aging

(2009) Olga A. Sedelnikova et al.   AGING CELL

Intercellular communication of cellular stress monitored by γ-H2AX induction

(2009) Jennifer S. Dickey et al.   CARCINOGENESIS

γ-H2AX Foci as a Biomarker for Patient X-Ray Exposure in Pediatric Cardiac Catheterization

(2009) Laurence Beels et al.   CIRCULATION

The heat-induced γ-H2AX response does not play a role in hyperthermic cell killing

(2009) Andrei Laszlo et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

H2AX phosphorylation as a genotoxicity endpoint

(2009) Gary Peter Watters et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

An in vitro micronucleus assay with size-classified micronucleus counting to discriminate aneugens from clastogens

(2009) Kiyohiro Hashimoto et al.   TOXICOLOGY IN VITRO