Gamma histone 2AX (γ-H2AX)as a predictive tool in radiation oncology
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Title
Gamma histone 2AX (γ-H2AX)as a predictive tool in radiation oncology
Authors
Keywords
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Journal
BIOMARKERS
Volume 19, Issue 3, Pages 167-180
Publisher
Informa UK Limited
Online
2014-03-10
DOI
10.3109/1354750x.2014.898099
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Note: Only part of the references are listed.- DNA mismatch repair protein MSH2 dictates cellular survival in response to low dose radiation in endometrial carcinoma cells
- (2013) Lynn M. Martin et al. CANCER LETTERS
- Inhibition of polo-like kinase 1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitisation
- (2013) Anita T. Tandle et al. EUROPEAN JOURNAL OF CANCER
- Relative biological effectiveness of mammography X-rays at the level of DNA and chromosomes in lymphocytes
- (2013) Julie Depuydt et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Relative biological efficiency of protons at low and therapeutic doses in induction of 53BP1/γH2AX foci in lymphocytes from umbilical cord blood
- (2013) Svetlana Sorokina et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- In Vitro and In Vivo Enhancement of Chemoradiation Using the Oral PARP Inhibitor ABT-888 in Colorectal Cancer Cells
- (2013) Joseph W. Shelton et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- ID1 affects the efficacy of radiotherapy in glioblastoma through inhibition of DNA repair pathways
- (2013) Qinhua Guo et al. MEDICAL ONCOLOGY
- Inhibiting UHRF1 expression enhances radiosensitivity in human esophageal squamous cell carcinoma
- (2013) Congrong Yang et al. MOLECULAR BIOLOGY REPORTS
- γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies
- (2013) Vanessa Valdiglesias et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Are mouse lens epithelial cells more sensitive to γ-irradiation than lymphocytes?
- (2013) Kristina Bannik et al. RADIATION AND ENVIRONMENTAL BIOPHYSICS
- Correlation of dynamic changes in γ-H2AX expression in peripheral blood lymphocytes from head and neck cancer patients with radiation-induced oral mucositis
- (2013) Ping Li et al. Radiation Oncology
- Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions
- (2013) Vincent A. Potiron et al. RADIOTHERAPY AND ONCOLOGY
- Residual γH2AX foci predict local tumour control after radiotherapy
- (2013) Ulrike Koch et al. RADIOTHERAPY AND ONCOLOGY
- HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity
- (2013) Thorsten Rieckmann et al. RADIOTHERAPY AND ONCOLOGY
- Dynamics of γH2AX formation and elimination in mammalian cells after X-irradiation
- (2012) Denis Firsanov et al. BIOCHIMIE
- The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy
- (2012) Remko Prevo et al. CANCER BIOLOGY & THERAPY
- Ferulic Acid Inhibits Gamma Radiation-Induced DNA Strand Breaks and Enhances the Survival of Mice
- (2012) Dharmendra Kumar Maurya et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Autocrine regulation of γ-irradiation-induced DNA damage response via extracellular nucleotides-mediated activation of P2Y6 and P2Y12 receptors
- (2012) Naoko Nishimaki et al. DNA REPAIR
- Targeting epidermal growth factor receptor/human epidermal growth factor receptor 2 signalling pathway by a dual receptor tyrosine kinase inhibitor afatinib for radiosensitisation in murine bladder carcinoma
- (2012) Yu-Chieh Tsai et al. EUROPEAN JOURNAL OF CANCER
- In vivo versus in vitro individual radiosensitivity analysed in healthy donors and in prostate cancer patients with and without severe side effects after radiotherapy
- (2012) Kinga Brzozowska et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Compromised hematopoiesis and increased DNA damage following non-lethal ionizing radiation of a human hematopoietic system reconstituted in immunodeficient mice
- (2012) Changshan Wang et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Radioprotective effect of hypothermia on cells – a multiparametric approach to delineate the mechanisms
- (2012) Li Dang et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- DNA damage response in CD133 + stem/progenitor cells from umbilical cord blood: Low level of endogenous foci and high recruitment of 53BP1
- (2012) Stanislav A. Vasilyev et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- DNA Double-Strand Break Analysis by γ-H2AX Foci: A Useful Method for Determining the Overreactors to Radiation-Induced Acute Reactions Among Head-and-Neck Cancer Patients
- (2012) Hassan Venkatesh Goutham et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Mangiferin aglycone attenuates radiation-induced damage on human intestinal epithelial cells
- (2012) Jixiao Lei et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The Defect of Ku70 Affects Sensitivity to X-Ray and Radiation-Induced Caspase-Dependent Apoptosis in Lung Cells
- (2012) Manabu KOIKE et al. JOURNAL OF VETERINARY MEDICAL SCIENCE
- Depletion of the type 1 IGF receptor delays repair of radiation-induced DNA double strand breaks
- (2012) Benjamin W. Turney et al. RADIOTHERAPY AND ONCOLOGY
- Suberoylanilide hydroxamic acid affects γH2AX expression in osteosarcoma, atypical teratoid rhabdoid tumor and normal tissue cell lines after irradiation
- (2012) C. Blattmann et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Radiosensitizing effect of epothilone B on human epithelial cancer cells
- (2012) T. Baumgart et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Radiation-induced blood–brain barrier damages: An in vitro study
- (2011) William Fauquette et al. BRAIN RESEARCH
- Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy
- (2011) Emil Kendziorra et al. CARCINOGENESIS
- Activation of DNA damage response signaling in mouse embryonic stem cells
- (2011) Ilya A. Chuykin et al. CELL CYCLE
- γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization
- (2011) Markus Löbrich et al. CELL CYCLE
- CD44 is a biomarker associated with human prostate cancer radiation sensitivity
- (2011) WeiWei Xiao et al. CLINICAL & EXPERIMENTAL METASTASIS
- TGF 1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In Vivo
- (2011) F. Bouquet et al. CLINICAL CANCER RESEARCH
- The presence of iodinated contrast agents amplifies DNA radiation damage in computed tomography
- (2011) Caroline Pathe et al. Contrast Media & Molecular Imaging
- Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment
- (2011) Emma C. Bourton et al. INTERNATIONAL JOURNAL OF CANCER
- DNA double-strand breaks induced by mammographic screening procedures in human mammary epithelial cells
- (2011) Catherine Colin et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Adamantanyl-Histone Deacetylase Inhibitor H6CAHA Exhibits Favorable Pharmacokinetics and Augments Prostate Cancer Radiation Sensitivity
- (2011) Zacharoula Konsoula et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- DNA damage response in resting and proliferating peripheral blood lymphocytes treated by camptothecin or X-ray
- (2011) Ming Tian et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Targeting Radiation-Induced G2 Checkpoint Activation with the Wee-1 Inhibitor MK-1775 in Glioblastoma Cell Lines
- (2011) B. Sarcar et al. MOLECULAR CANCER THERAPEUTICS
- Repeated exposure of human fibroblasts to ionizing radiation reveals an adaptive response that is not mediated by interleukin-6 or TGF-β
- (2011) Birger Dieriks et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells
- (2011) R. N. Fernando et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elevated radiation-induced γH2AX foci in G2 phase heterozygous BRCA2 fibroblasts
- (2011) Andrea Beucher et al. RADIOTHERAPY AND ONCOLOGY
- Residual DNA double strand breaks in perfused but not in unperfused areas determine different radiosensitivity of tumours
- (2011) Apostolos Menegakis et al. RADIOTHERAPY AND ONCOLOGY
- Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy
- (2011) Melvin Lee Kiang Chua et al. RADIOTHERAPY AND ONCOLOGY
- Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction
- (2010) L Stingl et al. BRITISH JOURNAL OF CANCER
- H2AX phosphorylation screen of cells from radiosensitive cancer patients reveals a novel DNA double-strand break repair cellular phenotype
- (2010) R S Vasireddy et al. BRITISH JOURNAL OF CANCER
- A Small Interfering RNA Screen of Genes Involved in DNA Repair Identifies Tumor-Specific Radiosensitization by POLQ Knockdown
- (2010) Geoff S. Higgins et al. CANCER RESEARCH
- DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue
- (2010) S. Jaamaa et al. CANCER RESEARCH
- Wip1 Directly Dephosphorylates -H2AX and Attenuates the DNA Damage Response
- (2010) H. Cha et al. CANCER RESEARCH
- "Contextual" Synthetic Lethality and/or Loss of Heterozygosity: Tumor Hypoxia and Modification of DNA Repair
- (2010) N. Chan et al. CLINICAL CANCER RESEARCH
- Circulating tumor cells: a window into cancer biology and metastasis
- (2010) Shyamala Maheswaran et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Lack of a correlation between γH2AX foci kinetics in lymphocytes and the severity of acute normal tissue reactions during IMRT treatment for head and neck cancer
- (2010) Joke Werbrouck et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Protection by methylproamine of irradiated human keratinocytes correlates with reduction of DNA damage
- (2010) Pavel N. Lobachevsky et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Accumulation of DNA Double-Strand Breaks in Normal Tissues After Fractionated Irradiation
- (2010) Claudia E. Rübe et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- DNA Repair Alterations in Children With Pediatric Malignancies: Novel Opportunities to Identify Patients at Risk for High-Grade Toxicities
- (2010) Claudia E. Rübe et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- The Impact of Individual In Vivo Repair of DNA Double-Strand Breaks on Oral Mucositis in Adjuvant Radiotherapy of Head-and-Neck Cancer
- (2010) Jochen Fleckenstein et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Radiosensitization of glioma cells by modulation of Met signalling with the hepatocyte growth factor neutralizing antibody, AMG102
- (2010) Ian M. Buchanan et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Early Increase of Radiation-induced γH2AX Foci in a Human Ku70/80 Knockdown Cell Line Characterized by an Enhanced Radiosensitivity
- (2010) Veerle VANDERSICKEL et al. JOURNAL OF RADIATION RESEARCH
- Detailed Analysis of DNA Repair and Senescence Marker Kinetics Over the Life Span of a Human Fibroblast Cell Line
- (2010) H. Endt et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Targeting Epidermal Growth Factor Receptor-Associated Signaling Pathways in Non-Small Cell Lung Cancer Cells: Implication in Radiation Response
- (2010) E. J. Choi et al. MOLECULAR CANCER RESEARCH
- Selective Inhibition of Histone Deacetylases Sensitizes Malignant Cells to Death Receptor Ligands
- (2010) T. E. Wood et al. MOLECULAR CANCER THERAPEUTICS
- Methylproamine protects against ionizing radiation by preventing DNA double-strand breaks
- (2010) Carl N. Sprung et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201
- (2010) Sergio Huerta et al. SURGERY
- H2AX Expression in Tumors Exposed to Cisplatin and Fractionated Irradiation
- (2009) C. A. Banuelos et al. CLINICAL CANCER RESEARCH
- In vitro and In vivo Radiosensitization of Glioblastoma Cells by the Poly (ADP-Ribose) Polymerase Inhibitor E7016
- (2009) A. L. Russo et al. CLINICAL CANCER RESEARCH
- Celastrol Potentiates Radiotherapy by Impairment of DNA Damage Processing in Human Prostate Cancer
- (2009) Yao Dai et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Phase 0 Clinical Trial of the Poly (ADP-Ribose) Polymerase Inhibitor ABT-888 in Patients With Advanced Malignancies
- (2009) Shivaani Kummar et al. JOURNAL OF CLINICAL ONCOLOGY
- Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts
- (2009) A. Baschnagel et al. MOLECULAR CANCER THERAPEUTICS
- Expression of Activated Checkpoint Kinase 2 and Histone 2AX in Exfoliative Oral Cells after Exposure to Ionizing Radiation
- (2009) Angela J. Yoon et al. RADIATION RESEARCH
- Endogenous and radiation-induced expression of γH2AX in biopsies from patients treated for carcinoma of the uterine cervix
- (2009) Peggy L. Olive et al. RADIOTHERAPY AND ONCOLOGY
- A low-dose hypersensitive keratinocyte loss in response to fractionated radiotherapy is associated with growth arrest and apoptosis
- (2009) Ingela Turesson et al. RADIOTHERAPY AND ONCOLOGY
- Tissue-specific DNA-PK-dependent H2AX phosphorylation and γ-H2AX elimination after X-irradiation in vivo
- (2008) Manabu Koike et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair
- (2008) R. Scott Williams et al. CELL
- A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia
- (2008) Paola Porcedda et al. CYTOMETRY PART A
- Mre11–Rad50–Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity
- (2008) Ali Jazayeri et al. EMBO JOURNAL
- Radiosensitization of cervical cancer cells via double-strand DNA break repair inhibition
- (2008) Christa B. Fuhrman et al. GYNECOLOGIC ONCOLOGY
- PX-478, an inhibitor of hypoxia-inducible factor-1α, enhances radiosensitivity of prostate carcinoma cells
- (2008) Sanjeewani T. Palayoor et al. INTERNATIONAL JOURNAL OF CANCER
- Bystander Effects Induced by Continuous Low-Dose-Rate 125I Seeds Potentiate the Killing Action of Irradiation on Human Lung Cancer Cells In Vitro
- (2008) Hong H. Chen et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- DNA Double-Strand Break Rejoining in Complex Normal Tissues
- (2008) Claudia E. Rübe et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Celecoxib Induced Tumor Cell Radiosensitization by Inhibiting Radiation Induced Nuclear EGFR Transport and DNA-Repair: A COX-2 Independent Mechanism
- (2007) Klaus H. Dittmann et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Residual γH2AX after irradiation of human lymphocytes and monocytes in vitro and its relation to late effects after prostate brachytherapy
- (2007) Peggy L. Olive et al. RADIOTHERAPY AND ONCOLOGY
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