Acute and Long-Term Effects of Brief Sevoflurane Anesthesia During the Early Postnatal Period in Rats

Brain Maturation in Neonatal Rodents Is Impeded by Sevoflurane Anesthesia

(2015) Rany Makaryus et al.   ANESTHESIOLOGY

Long-term Effects of Single or Multiple Neonatal Sevoflurane Exposures on Rat Hippocampal Ultrastructure

(2015) Levana G. Amrock et al.   ANESTHESIOLOGY

Multiple Anesthetic Exposure in Infant Monkeys Alters Emotional Reactivity to an Acute Stressor

(2015) Jessica Raper et al.   ANESTHESIOLOGY

Anesthetic Neurotoxicity — Clinical Implications of Animal Models

(2015) Bob A. Rappaport et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sevoflurane exposure during the neonatal period induces long-term memory impairment but not autism-like behaviors

(2015) Woosuk Chung et al.   PEDIATRIC ANESTHESIA

Potential Adverse Effects of Prolonged Sevoflurane Exposure on Developing Monkey Brain: From Abnormal Lipid Metabolism to Neuronal Damage

(2015) Fang Liu et al.   TOXICOLOGICAL SCIENCES

Finding Our Way through Phenotypes

(2015) Andrew R. Deans et al.   PLOS BIOLOGY

Pushing the Standards Forward

(2014) Laszlo Vutskits et al.   ANESTHESIA AND ANALGESIA

General Anesthetic Isoflurane Modulates Inositol 1,4,5-Trisphosphate Receptor Calcium Channel Opening

(2014) J. Donald Joseph et al.   ANESTHESIOLOGY

Clinical Research Into Anesthetic Neurotoxicity

(2014) Susan Y. Lei et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

Cation-chloride cotransporters in neuronal development, plasticity and disease

(2014) Kai Kaila et al.   NATURE REVIEWS NEUROSCIENCE

Physiological Disturbance May Contribute to Neurodegeneration Induced by Isoflurane or Sevoflurane in 14 Day Old Rats

(2014) Binbin Wu et al.   PLoS One

Researchers struggle to gauge risks of childhood anesthesia

(2014) Kelly Servick   SCIENCE

Neonatal Exposure to Sevoflurane Causes Significant Suppression of Hippocampal Long-Term Potentiation in Postgrowth Rats

(2013) Rui Kato et al.   ANESTHESIA AND ANALGESIA

Selective Anesthesia-induced Neuroinflammation in Developing Mouse Brain and Cognitive Impairment

(2013) Xia Shen et al.   ANESTHESIOLOGY

Cell age-specific vulnerability of neurons to anesthetic toxicity

(2013) Rylon D. Hofacer et al.   ANNALS OF NEUROLOGY

General anaesthetics do not impair developmental expression of the KCC2 potassium-chloride cotransporter in neonatal rats during the brain growth spurt

(2013) C.-M. Lacoh et al.   BRITISH JOURNAL OF ANAESTHESIA

Loss of hippocampal neurogenesis, increased novelty-induced activity, decreased home cage activity, and impaired reversal learning one year after irradiation of the young mouse brain

(2013) Marie Kalm et al.   EXPERIMENTAL NEUROLOGY

Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline

(2013) Niccolò Terrando et al.   FASEB JOURNAL

Functional Implications of an Early Exposure to General Anesthesia: Are We Changing the Behavior of Our Children?

(2013) Vesna Jevtovic-Todorovic   MOLECULAR NEUROBIOLOGY

Early life exposure to sevoflurane impairs adulthood spatial memory in the rat

(2013) Xiaofeng Shen et al.   NEUROTOXICOLOGY

Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

(2013) Bridgette D. Semple et al.   PROGRESS IN NEUROBIOLOGY

General Anesthesia

(2012) Laszlo Vutskits   ANESTHESIA AND ANALGESIA

An Ion Transport-Independent Role for the Cation-Chloride Cotransporter KCC2 in Dendritic Spinogenesis In Vivo

(2012) H. Fiumelli et al.   CEREBRAL CORTEX

Anesthetics and the developing brain: time for a change in practice? A pro/con debate

(2012) Laszlo Vutskits et al.   PEDIATRIC ANESTHESIA

Developmental Stage-dependent Persistent Impact of Propofol Anesthesia on Dendritic Spines in the Rat Medial Prefrontal Cortex

(2011) Adrian Briner et al.   ANESTHESIOLOGY

Volatile Anesthetics Rapidly Increase Dendritic Spine Density in the Rat Medial Prefrontal Cortex during Synaptogenesis

(2010) Adrian Briner et al.   ANESTHESIOLOGY

Isoflurane Anesthesia Induced Persistent, Progressive Memory Impairment, Caused a Loss of Neural Stem Cells, and Reduced Neurogenesis in Young, but Not Adult, Rodents

(2010) Changlian Zhu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Isoflurane Differentially Affects Neurogenesis and Long-term Neurocognitive Function in 60-day-old and 7-day-old Rats

(2009) Greg Stratmann et al.   ANESTHESIOLOGY

General Anesthesia Causes Long-Lasting Disturbances in the Ultrastructural Properties of Developing Synapses in Young Rats

(2009) N. Lunardi et al.   NEUROTOXICITY RESEARCH