α-Synuclein Oligomers Induced by Docosahexaenoic Acid Affect Membrane Integrity

Oxidative stress-induced posttranslational modifications of alpha-synuclein: Specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity

(2013) Wei Xiang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Lipid Peroxidation Product 4-Hydroxy-2-Nonenal Promotes Seeding-Capable Oligomer Formation and Cell-to-Cell Transfer of α-Synuclein

(2012) Eun-Jin Bae et al.   ANTIOXIDANTS & REDOX SIGNALING

Alpha-synuclein pore forming activity upon membrane association

(2012) Laura Tosatto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

What does make an amyloid toxic: Morphology, structure or interaction with membrane?

(2012) Karine Berthelot et al.   BIOCHIMIE

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

 -Synuclein Inhibits Intersynaptic Vesicle Mobility and Maintains Recycling-Pool Homeostasis

(2012) D. Scott et al.   JOURNAL OF NEUROSCIENCE

The many faces of α-synuclein: from structure and toxicity to therapeutic target

(2012) Hilal A. Lashuel et al.   NATURE REVIEWS NEUROSCIENCE

α-Synuclein Neuropathology is Controlled by Nuclear Hormone Receptors and Enhanced by Docosahexaenoic Acid in A Mouse Model for Parkinson's Disease

(2011) Eugenia Yakunin et al.   BRAIN PATHOLOGY

Structural and Morphological Characterization of Aggregated Species of α-Synuclein Induced by Docosahexaenoic Acid

(2011) Giorgia De Franceschi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Membrane Interaction and Disruption by α-Synuclein

(2011) Nicholas P. Reynolds et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Low-resolution structure of a vesicle disrupting  -synuclein oligomer that accumulates during fibrillation

(2011) L. Giehm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloidogenic Protein-Membrane Interactions: Mechanistic Insight from Model Systems

(2010) Sara M. Butterfield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α-Synuclein: Membrane Interactions and Toxicity in Parkinson's Disease

(2010) Pavan K. Auluck et al.   Annual Review of Cell and Developmental Biology

Fluctuations and the Rate-Limiting Step of Peptide-Induced Membrane Leakage

(2010) C. Mazzuca et al.   BIOPHYSICAL JOURNAL

The N-Terminus of the Intrinsically Disordered Protein α-Synuclein Triggers Membrane Binding and Helix Folding

(2010) Tim Bartels et al.   BIOPHYSICAL JOURNAL

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

Membrane Permeabilization by Oligomeric α-Synuclein: In Search of the Mechanism

(2010) Bart D. van Rooijen et al.   PLoS One

Alpha-synuclein, lipids and Parkinson’s disease

(2010) Violeta Ruipérez et al.   PROGRESS IN LIPID RESEARCH

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

Molecular Insights into the Interaction between α-Synuclein and Docosahexaenoic Acid

(2009) Giorgia De Franceschi et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Properties of Pore-Forming Oligomers of α-Synuclein

(2009) Hai-Young Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Membrane binding of oligomeric α-synuclein depends on bilayer charge and packing

(2008) Bart D. van Rooijen et al.   FEBS LETTERS

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

(2008) Claire Henchcliffe et al.   Nature clinical practice. Neurology