Enantioselective synthesis of α-perfluoroalkylated prolines, their 6,7-membered homologues and derivatives

Internally Reuse Waste: Catalytic Asymmetric One-Pot Strecker Reaction of Fluoroalkyl Ketones, Anilines and TMSCN by Sequential Catalysis

(2018) Yun-Lin Liu et al.   CHINESE JOURNAL OF CHEMISTRY

Biobased Amines: From Synthesis to Polymers; Present and Future

(2016) Vincent Froidevaux et al.   CHEMICAL REVIEWS

Effect of Partially FluorinatedN-Alkyl-Substituted Piperidine-2-carboxamides on Pharmacologically Relevant Properties

(2016) Raffael Vorberg et al.   ChemMedChem

Origins of Stereoselectivity of Chiral Vicinal Diamine-Catalyzed Aldol Reactions

(2016) Adam Simon et al.   JOURNAL OF ORGANIC CHEMISTRY

Incorporation of Trifluoromethylated Proline and Surrogates into Peptides: Application to the Synthesis of Fluorinated Analogues of the Neuroprotective Glycine-Proline-Glutamate (GPE) Tripeptide

(2016) Julien Simon et al.   JOURNAL OF ORGANIC CHEMISTRY

In Vitro selectivity of an acyclic cucurbit[n]uril molecular container towards neuromuscular blocking agents relative to commonly used drugs

(2016) Shweta Ganapati et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Update on local anesthetics: focus on levobupivacaine

(2016) C L Burlacu   Therapeutics and Clinical Risk Management

Protein-Observed Fluorine NMR: A Bioorthogonal Approach for Small Molecule Discovery

(2015) Keith E. Arntson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorinated Proteins: From Design and Synthesis to Structure and Stability

(2014) E. Neil G. Marsh   ACCOUNTS OF CHEMICAL RESEARCH

Intrathecal bupivacaine or levobupivacaine: Which should be used for elderly patients?

(2014) Demet Gulec et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Construction of Optically Active Quaternary Propargyl Amines by Highly Enantioselective Zinc/BINOL-Catalyzed Alkynylation of Ketoimines

(2013) Gaochao Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Strecker Reaction with Chiral Amines: a Catalyst-Free Protocol Using Acetone Cyanohydrin in Water

(2013) Matteo Pori et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic enantioselective Strecker reaction of cyclic trifluoromethyl-ketoimines

(2013) Hexin Xie et al.   TETRAHEDRON LETTERS

Highly enantioselective organocatalytic Strecker reaction of cyclic N-acyl trifluoromethylketimines: synthesis of anti-HIV drug DPC 083

(2012) Fa-Guang Zhang et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric cyanation of isatin derived N-Boc ketoimines

(2012) Yun-Lin Liu et al.   CHEMICAL COMMUNICATIONS

Stereoselective Access to Fluorinated and Non-fluorinated Quaternary Piperidines: Synthesis of Pipecolic Acid and Iminosugar Derivatives

(2012) Santos Fustero et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Regio-specific solvent controlled asymmetric Strecker reaction of trifluoromethyl α,β-unsaturated N-tert-butanesulfinyl ketimines with trimethylsilyl cyanide

(2012) Xiao-Ming Yuan et al.   JOURNAL OF FLUORINE CHEMISTRY

Stereocontrolled Synthesis of Vicinal Diamines by Organocatalytic Asymmetric Mannich Reaction of N-Protected Aminoacetaldehydes: Formal Synthesis of (−)-Agelastatin A

(2012) Taichi Kano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Strecker Reactions

(2011) Jun Wang et al.   CHEMICAL REVIEWS

Fluorinated amino acids: compatibility with native protein structures and effects on protein–protein interactions

(2011) Mario Salwiczek et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium-Catalysed Synthesis of Fluorinated Bicyclic Amino Esters through Tandem Carbene Addition/Cyclopropanation of Enynes

(2011) Matthieu Eckert et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Advances in the Synthesis of Fluorinated Amino Acids

(2011) Xiao-Long Qiu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Asymmetric Strecker Reaction of Di- and Trifluoromethyl Ketoimines. Remarkable Fluorine Effect

(2011) Yun-Lin Liu et al.   ORGANIC LETTERS

Organocatalytic Enantioselective Strecker Synthesis of α-Quaternary α-Trifluoromethyl Amino Acids

(2010) Dieter Enders et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Scaleable catalytic asymmetric Strecker syntheses of unnatural α-amino acids

(2009) Stephan J. Zuend et al.   NATURE

Synthetic strategies to α-trifluoromethyl and α-difluoromethyl substituted α-amino acids

(2008) René Smits et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of lidocaine-loaded PLGA microparticles by flow focusing

(2008) M.A. Holgado et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Synthesis of Enantiopure Fmoc-α-Methylvaline

(2008) Lianhe Shu et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Chiral Tertiary Diamines in Asymmetric Synthesis

(2007) Jean-Claude Kizirian   CHEMICAL REVIEWS