NHC-mediated cross-coupling of sugar-derived cyclic nitrones with enals: general and efficient synthesis of polyhydroxylated pyrrolizidines and indolizidines

General Synthesis of Sugar-Derived Azepane Nitrones: Precursors of Azepane Iminosugars

(2013) Wen-Bo Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

(2012) Julien Dugal-Tessier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

(2012) Javier Izquierdo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlled β-protonation and [4+2] cycloaddition of enals and chalconesvia N-heterocyclic carbene/acid catalysis: toward substrate independent reaction control

(2012) Zhenqian Fu et al.   CHEMICAL COMMUNICATIONS

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Structure, Biological Activities and Synthesis of Hyacinthacine Alkaloids and Their Stereoisomers

(2012) Thunwadee Ritthiwigrom et al.   CURRENT ORGANIC SYNTHESIS

Fast Pd- and Pd/Cu-Catalyzed Direct C–H Arylation of Cyclic Nitrones. Application to the Synthesis of Enantiopure Quaternary α-Amino Esters

(2012) Emilien Demory et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Alkaloid (−)-205B via Stereoselective Reductive Cross-Coupling and Intramolecular [3+2] Cycloaddition

(2012) Dexi Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Access to l- and d-Iminosugar C-Glycosides from a d-gluco-Derived 6-Azidolactol Exploiting a Ring Isomerization/Alkylation Strategy

(2012) Martine Mondon et al.   ORGANIC LETTERS

Azetidine Iminosugars from the Cyclization of 3,5-Di-O-triflates of α-Furanosides and of 2,4-Di-O-triflates of β-Pyranosides Derived from Glucose

(2012) Gabriel M. J. Lenagh-Snow et al.   ORGANIC LETTERS

SmI2-Mediated Cross-Coupling of Nitrones with β-Silyl Acrylates: Synthesis of (+)-Australine

(2012) Pierre Gilles et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic Routes to N-Heterocyclic Carbene Precursors

(2011) Laure Benhamou et al.   CHEMICAL REVIEWS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Total Synthesis of (+)-Hyacinthacine A1, (+)-7a-epi-Hyacinthacine A1, (6R)-6-Hydroxyhyacinthacine A1 and (6S)-6-Hydroxy-7a-epi-hyacinthacine A1

(2011) Giampiero D'Adamio et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Sequential Nucleophilic Addition/Intramolecular Cycloaddition to Chiral Nonracemic Cyclic Nitrones: A Highly Stereoselective Approach to Polyhydroxynortropane Alkaloids

(2011) Ignacio Delso et al.   JOURNAL OF ORGANIC CHEMISTRY

l-DMDP, l-homoDMDP and their C-3 fluorinated derivatives: synthesis and glycosidase-inhibition

(2011) Yi-Xian Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A concise stereoselective synthesis of (−)-erycibelline

(2011) Zhao-Lan Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope–House Cyclization

(2011) Wei Zhang et al.   ORGANIC LETTERS

Beyond catalysis: N-heterocyclic carbene complexes as components for medicinal, luminescent, and functional materials applications

(2010) Laszlo Mercs et al.   CHEMICAL SOCIETY REVIEWS

Synthesis, Biological Evaluation and Docking Studies of Casuarine Analogues: Effects of Structural Modifications at Ring B on Inhibitory Activity Towards Glucoamylase

(2010) Claudia Bonaccini et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

CooperativeN-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates

(2010) Benoit Cardinal-David et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Glycosidase Inhibition of the Enantiomer of (−)-Steviamine, the First Example of a New Class of Indolizidine Alkaloid

(2010) Xiang-Guo Hu et al.   ORGANIC LETTERS

Synthesis of 2-acetamido-1,2-dideoxy-d-galacto-nojirimycin [DGJNAc] from d-glucuronolactone: the first sub-micromolar inhibitor of α-N-acetylgalactosaminidases

(2010) Daniel Best et al.   TETRAHEDRON LETTERS

Looking glass inhibitors: scalable syntheses of DNJ, DMDP, and (3R)-3-hydroxy-l-bulgecinine from d-glucuronolactone and of l-DNJ, l-DMDP, and (3S)-3-hydroxy-d-bulgecinine from l-glucuronolactone. DMDP inhibits β-glucosidases and β-galactosidases whereas l-DMDP is a potent and specific inhibitor of α-glucosidases

(2010) Daniel Best et al.   TETRAHEDRON-ASYMMETRY

Stereocontrolled Cyclic Nitrone Cycloaddition Strategy for the Synthesis of Pyrrolizidine and Indolizidine Alkaloids

(2009) Alberto Brandi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis of (−)-Uniflorine A⊥

(2009) Camilla Parmeggiani et al.   JOURNAL OF NATURAL PRODUCTS

Novel Nucleophilic Heterocyclic Carbene Mediated Stereoselective Conjugate Addition of Enals to Nitrostyrenes via Homoenolate§

(2009) Vijay Nair et al.   ORGANIC LETTERS

Synthesis of d-arabinose-derived polyhydroxylated pyrrolidine, indolizidine and pyrrolizidine alkaloids. Total synthesis of hyacinthacine A2

(2009) Ignacio Delso et al.   TETRAHEDRON

Iminosugars: from botanical curiosities to licensed drugs

(2009) Bryan G. Winchester   TETRAHEDRON-ASYMMETRY

Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed byN-Heterocyclic Carbenes

(2008) Eric M. Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient stereoselective nucleophilic addition of pyrroles to chiral nitrones

(2008) Christophe Berini et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of (+)-Uniflorine A: A Structural Reassignment and a Configurational Assignment†

(2008) Thunwadee Ritthiwigrom et al.   ORGANIC LETTERS

A convenient approach toward the synthesis of enantiopure isomers of DMDP and ADMDP

(2008) En-Lun Tsou et al.   TETRAHEDRON