PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612

Long non-coding RNA NEAT1 is a transcriptional target of p53 and modulates p53-induced transactivation and tumor-suppressor function

(2017) Masashi Idogawa et al.   INTERNATIONAL JOURNAL OF CANCER

WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms

(2017) Hyung Chul Lee et al.   NUCLEIC ACIDS RESEARCH

RNA-Binding Proteins Revisited – The Emerging Arabidopsis mRNA Interactome

(2017) Tino Köster et al.   TRENDS IN PLANT SCIENCE

Long noncoding RNA NEAT1 promotes cell proliferation and invasion by regulating hnRNP A2 expression in hepatocellular carcinoma cells

(2017) Yuanyi Mang et al.   OncoTargets and Therapy

GOLM1 Modulates EGFR/RTK Cell-Surface Recycling to Drive Hepatocellular Carcinoma Metastasis

(2016) Qing-Hai Ye et al.   CANCER CELL

Genomic variations in non-coding RNAs: Structure, function and regulation

(2016) Deeksha Bhartiya et al.   GENOMICS

Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay

(2016) Li Zhang et al.   HEPATOLOGY

Comprehensive Identification of RNA-Binding Domains in Human Cells

(2016) Alfredo Castello et al.   MOLECULAR CELL

p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity

(2016) Carmen Adriaens et al.   NATURE MEDICINE

RNA Binding Protein Ptbp2 Is Essential for Male Germ Cell Development

(2015) Leah L. Zagore et al.   MOLECULAR AND CELLULAR BIOLOGY

Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation

(2015) L.-Y. Tan et al.   NUCLEIC ACIDS RESEARCH

Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells

(2015) S Calabretta et al.   ONCOGENE

Long non-coding RNA MALAT1 promotes tumour growth and metastasis in colorectal cancer through binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex

(2014) Q Ji et al.   BRITISH JOURNAL OF CANCER

Long Noncoding RNA NEAT1-Dependent SFPQ Relocation from Promoter Region to Paraspeckle Mediates IL8 Expression upon Immune Stimuli

(2014) Katsutoshi Imamura et al.   MOLECULAR CELL

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphorothioate oligonucleotides can displaceNEAT1RNA and form nuclear paraspeckle-like structures

(2014) Wen Shen et al.   NUCLEIC ACIDS RESEARCH

Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

(2014) H Choudhry et al.   ONCOGENE

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer

(2014) Dimple Chakravarty et al.   Nature Communications

miR-612 suppresses the invasive-metastatic cascade in hepatocellular carcinoma

(2013) Zhong-Hua Tao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Paraspeckle formation during the biogenesis of long non-coding RNAs

(2013) Takao Naganuma et al.   RNA Biology

Long non-coding RNAgadd7interacts with TDP-43 and regulatesCdk6mRNA decay

(2012) Xuefeng Liu et al.   EMBO JOURNAL

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain

(2012) D. D. Licatalosi et al.   GENES & DEVELOPMENT

Turning on a Fuel Switch of Cancer: hnRNP Proteins Regulate Alternative Splicing of Pyruvate Kinase mRNA

(2010) M. Chen et al.   CANCER RESEARCH

Effect of Nitroxoline on Angiogenesis and Growth of Human Bladder Cancer

(2010) Joong Sup Shim et al.   JNCI-Journal of the National Cancer Institute

Phylogenetic and expression analysis of RNA-binding proteins with triple RNA recognition motifs in plants

(2010) Lila Peal et al.   MOLECULES AND CELLS

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

(2010) C. V. Clower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines

(2009) Hannah C. Cheung et al.   BRAIN

Biomarkers for epithelial-mesenchymal transitions

(2009) Michael Zeisberg et al.   JOURNAL OF CLINICAL INVESTIGATION

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL