−7/7q− syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
−7/7q− syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity
Authors
Keywords
-
Journal
ONCOGENE
Volume 34, Issue 19, Pages 2413-2425
Publisher
Springer Nature
Online
2014-07-07
DOI
10.1038/onc.2014.196
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Evi1 forms a bridge between the epigenetic machinery and signaling pathways
- (2015) Akihide Yoshimi et al. Oncotarget
- The role of EVI1 in myeloid malignancies
- (2014) Carolyn Glass et al. BLOOD CELLS MOLECULES AND DISEASES
- MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
- (2014) Chong Chen et al. CANCER CELL
- Recurrent genetic defects on chromosome 7q in myeloid neoplasms
- (2014) N Hosono et al. LEUKEMIA
- Enhancer Malfunction in Cancer
- (2014) Hans-Martin Herz et al. MOLECULAR CELL
- Identification of genomic alterations in oesophageal squamous cell cancer
- (2014) Yongmei Song et al. NATURE
- Clinical implications of theSETBP1mutation in patients with primary myelodysplastic syndrome and its stability during disease progression
- (2013) Hsin-An Hou et al. AMERICAN JOURNAL OF HEMATOLOGY
- Hematopoietic Stem Cell Transplantation in Children and Young Adults with Secondary Myelodysplastic Syndrome and Acute Myelogenous Leukemia after Aplastic Anemia
- (2013) Ayami Yoshimi et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Analysis of risk factors influencing outcomes after cord blood transplantation in children with juvenile myelomonocytic leukemia: a EUROCORD, EBMT, EWOG-MDS, CIBMTR study
- (2013) F. Locatelli et al. BLOOD
- Genomic impact of transient low-dose decitabine treatment on primary AML cells
- (2013) J. M. Klco et al. BLOOD
- CUX1 in leukemia: dosage matters
- (2013) J. Boultwood BLOOD
- p15Ink4b Functions in determining hematopoietic cell fates: Implications for its role as a tumor suppressor
- (2013) Linda Wolff et al. BLOOD CELLS MOLECULES AND DISEASES
- Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7
- (2013) Akiko Nagamachi et al. CANCER CELL
- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
- (2013) Hui Yang et al. CELL
- A role for RUNX1 in hematopoiesis and myeloid leukemia
- (2013) Motoshi Ichikawa et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders
- (2013) Tomoya Muto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias
- (2013) F Damm et al. LEUKEMIA
- Epigenetics in clinical practice: the examples of azacitidine and decitabine in myelodysplasia and acute myeloid leukemia
- (2013) E H Estey LEUKEMIA
- SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations
- (2013) M Meggendorfer et al. LEUKEMIA
- Epigenetics of myelodysplastic syndromes
- (2013) R Itzykson et al. LEUKEMIA
- Validation of the revised International Prognostic Scoring System (IPSS-R) in patients with myelodysplastic syndrome: A multicenter study
- (2013) Judith Neukirchen et al. LEUKEMIA RESEARCH
- Allelic imbalance in 1p, 7q, 9p, 11p, 12q and 16q regions in non-small cell lung carcinoma and its clinical association: a pilot study
- (2013) Karolina H. Czarnecka et al. MOLECULAR BIOLOGY REPORTS
- Inactivating CUX1 mutations promote tumorigenesis
- (2013) Chi C Wong et al. NATURE GENETICS
- EZH2 Mutations Are Related to Low Blast Percentage in Bone Marrow and -7/del(7q) in De Novo Acute Myeloid Leukemia
- (2013) Xiuli Wang et al. PLoS One
- Putative RNA-splicing gene LUC7L2 on 7q34 represents a candidate gene in pathogenesis of myeloid malignancies
- (2013) H Singh et al. Blood Cancer Journal
- DOCK4 deletion at 7q31.1 in a de novo acute myeloid leukemia with a normal karyotype
- (2013) Eigil Kjeldsen et al. CELLULAR ONCOLOGY
- Sole abnormalities of chromosome 7 in myeloid malignancies: Spectrum, histopathologic correlates, and prognostic implications
- (2012) Fareeda Taher Nazer Hussain et al. AMERICAN JOURNAL OF HEMATOLOGY
- Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS
- (2012) L. Barreyro et al. BLOOD
- High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations
- (2012) M. W. M. Kuhn et al. BLOOD
- How I treat newly diagnosed chronic phase CML
- (2012) J. Cortes et al. BLOOD
- Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
- (2012) H. Makishima et al. BLOOD
- CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia
- (2012) M. E. McNerney et al. BLOOD
- Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis
- (2012) A. Jerez et al. BLOOD
- Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing
- (2012) A. Dolnik et al. BLOOD
- Revised International Prognostic Scoring System for Myelodysplastic Syndromes
- (2012) P. L. Greenberg et al. BLOOD
- Predicting survival of patients with hypocellular myelodysplastic syndrome
- (2012) Wei-Gang Tong et al. CANCER
- CUX1 transcription factors: From biochemical activities and cell-based assays to mouse models and human diseases
- (2012) Laura Hulea et al. GENE
- A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia
- (2012) C. Simon et al. GENES & DEVELOPMENT
- Transcription Factor CUTL1 Is a Negative Regulator of Drug Resistance in Gastric Cancer
- (2012) Tingting Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Validation of a Prognostic Model and the Impact of Mutations in Patients With Lower-Risk Myelodysplastic Syndromes
- (2012) Rafael Bejar et al. JOURNAL OF CLINICAL ONCOLOGY
- Directed therapy for patients with myelodysplastic syndromes (MDS) by suppression of cyclin D1 with ON 01910.Na
- (2012) Matthew J. Olnes et al. LEUKEMIA RESEARCH
- Poly-ADP Ribosylation of Miki by tankyrase-1 Promotes Centrosome Maturation
- (2012) Yuko Ozaki et al. MOLECULAR CELL
- EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
- (2012) Michael T. McCabe et al. NATURE
- The microcosmos of cancer
- (2012) Amaia Lujambio et al. NATURE
- Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
- (2012) Zhi Jiang Zang et al. NATURE GENETICS
- Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia
- (2012) Jay P. Patel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease
- (2012) A. Herrera-Merchan et al. Nature Communications
- Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
- (2011) C. A. Dinarello BLOOD
- TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome
- (2011) F. G. Rucker et al. BLOOD
- Better prognosis for patients with del(7q) than for patients with monosomy 7 in myelodysplastic syndrome
- (2011) Iris Cordoba et al. CANCER
- Cytogenetic abnormalities in myelodysplastic syndrome: an overview
- (2011) Nikesh Kawankar et al. Hematology
- DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population
- (2011) Anna Alkelai et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Aberrant Epigenetic and Genetic Marks Are Seen in Myelodysplastic Leukocytes and RevealDock4as a Candidate Pathogenic Gene on Chromosome 7q
- (2011) Li Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Low-Dose Decitabine Versus Best Supportive Care in Elderly Patients With Intermediate- or High-Risk Myelodysplastic Syndrome (MDS) Ineligible for Intensive Chemotherapy: Final Results of the Randomized Phase III Study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group
- (2011) Michael Lübbert et al. JOURNAL OF CLINICAL ONCOLOGY
- RUNX1 Mutations in Acute Myeloid Leukemia: Results From a Comprehensive Genetic and Clinical Analysis From the AML Study Group
- (2011) Verena I. Gaidzik et al. JOURNAL OF CLINICAL ONCOLOGY
- Treatment of higher risk myelodysplastic syndrome patients unresponsive to hypomethylating agents with ON 01910.Na
- (2011) Mahesh Seetharam et al. LEUKEMIA RESEARCH
- Epigenetic regulation of microRNAs in cancer: An integrated review of literature
- (2011) Tanja Kunej et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- (2011) Johannes Zuber et al. NATURE
- Frequent pathway mutations of splicing machinery in myelodysplasia
- (2011) Kenichi Yoshida et al. NATURE
- A continuum model for tumour suppression
- (2011) Alice H. Berger et al. NATURE
- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
- (2011) Mark A. Dawson et al. NATURE
- Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
- (2011) Yaoting Gui et al. NATURE GENETICS
- Non-coding RNAs in human disease
- (2011) Manel Esteller NATURE REVIEWS GENETICS
- Clinical Effect of Point Mutations in Myelodysplastic Syndromes
- (2011) Rafael Bejar et al. NEW ENGLAND JOURNAL OF MEDICINE
- AML1/RUNX1 gene point mutations in childhood myeloid malignancies
- (2011) Alexandr Migas et al. PEDIATRIC BLOOD & CANCER
- Factors influencing a second myeloid malignancy in patients with Philadelphia-negative -7 or del(7q) clones during tyrosine kinase inhibitor therapy for chronic myeloid leukemia
- (2011) Michael J. Groves et al. Cancer Genetics
- Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies
- (2010) J. C. Y. Wong et al. BLOOD
- Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
- (2010) D. B. Yap et al. BLOOD
- Advances in the 5q- syndrome
- (2010) J. Boultwood et al. BLOOD
- Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome
- (2010) G. Gohring et al. BLOOD
- Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
- (2010) D. Grimwade et al. BLOOD
- Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: azacitidine compared with low dose ara-C
- (2010) Pierre Fenaux et al. BRITISH JOURNAL OF HAEMATOLOGY
- Genetic analysis of dasatinib-treated chronic myeloid leukemia rapidly developing into acute myeloid leukemia with monosomy 7 in Philadelphia-negative cells
- (2010) Nina Larsson et al. CANCER GENETICS AND CYTOGENETICS
- Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing
- (2010) Khairul I. Ansari et al. FEBS Journal
- RUNX1translocations and fusion genes in malignant hemopathies
- (2010) Etienne De Braekeleer et al. Future Oncology
- Clinical, Molecular, and Prognostic Significance of WHO Type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and Various Other 3q Abnormalities in Acute Myeloid Leukemia
- (2010) Sanne Lugthart et al. JOURNAL OF CLINICAL ONCOLOGY
- HighEVI1Expression Predicts Outcome in Younger Adult Patients With Acute Myeloid Leukemia and Is Associated With Distinct Cytogenetic Abnormalities
- (2010) Stefan Gröschel et al. JOURNAL OF CLINICAL ONCOLOGY
- Functional Characterization of SAMD9, a Protein Deficient in Normophosphatemic Familial Tumoral Calcinosis
- (2010) Dov Hershkovitz et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia
- (2010) B V Balgobind et al. LEUKEMIA
- Analysis of risk factors influencing outcome in children with myelodysplastic syndrome after unrelated cord blood transplantation
- (2010) A B M Madureira et al. LEUKEMIA
- Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells
- (2010) A Pellagatti et al. LEUKEMIA
- Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
- (2010) Gorica Nikoloski et al. NATURE GENETICS
- Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
- (2010) Ryan D Morin et al. NATURE GENETICS
- Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
- (2010) Thomas Ernst et al. NATURE GENETICS
- Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
- (2010) Stefan Stein et al. NATURE MEDICINE
- Identification of Two Critically Deleted Regions within Chromosome Segment 7q35-q36 in EVI1 Deregulated Myeloid Leukemia Cell Lines
- (2010) An De Weer et al. PLoS One
- Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
- (2010) C. J. Sneeringer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Genetic Landscape of the Childhood Cancer Medulloblastoma
- (2010) D. W. Parsons et al. SCIENCE
- Identification of a common microdeletion cluster in 7q21.3 subband among patients with myeloid leukemia and myelodysplastic syndrome
- (2009) Hiroya Asou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SETBP1 overexpression is a novel leukemogenic mechanism that predicts adverse outcome in elderly patients with acute myeloid leukemia
- (2009) I. Cristobal et al. BLOOD
- Does MDS with der(1;7)(q10;p10) constitute a distinct risk group? A retrospective single institutional analysis of clinical/pathologic features compared to –7/del(7q) MDS
- (2009) Marilyn L. Slovak et al. CANCER GENETICS AND CYTOGENETICS
- Mouse Mammary Tumor Virus p75 and p110 CUX1 Transgenic Mice Develop Mammary Tumors of Various Histologic Types
- (2009) C. Cadieux et al. CANCER RESEARCH
- Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells
- (2009) Tim C.P. Somervaille et al. Cell Stem Cell
- Epigenetic changes in therapy-related MDS/AML
- (2009) Maria Teresa Voso et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Cytogenetic and genetic pathways in therapy-related acute myeloid leukemia
- (2009) Zhijian Qian et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Identifying the molecular signature of the interstitial deletion 7q subgroup of uterine leiomyomata using a paired analysis
- (2009) Jennelle C. Hodge et al. GENES CHROMOSOMES & CANCER
- Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
- (2009) Pierre Fenaux et al. LANCET ONCOLOGY
- p15INK4b methylation correlates with thrombocytopenia, blast percentage, and survival in myelodysplastic syndromes in a dose dependent manner: Quantitation using pyrosequencing study
- (2009) Miyoung Kim et al. LEUKEMIA RESEARCH
- High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L–DOCK4 gene region in autism susceptibility
- (2009) E Maestrini et al. MOLECULAR PSYCHIATRY
- In Brief
- (2009) NATURE REVIEWS NEUROSCIENCE
- Treatment of children with refractory anemia: The Japanese Childhood MDS Study Group trial (MDS99)
- (2009) Daisuke Hasegawa et al. PEDIATRIC BLOOD & CANCER
- AML1 mutations induced MDS and MDS/AML in a mouse BMT model
- (2008) N. Watanabe-Okochi et al. BLOOD
- Cytogenetic abnormalities in a series of 1029 patients with primary myelodysplastic syndromes
- (2008) Olga Pozdnyakova et al. CANCER
- A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a
- (2008) Dominik Spensberger et al. FEBS LETTERS
- The multiple roles of CUX1: Insights from mouse models and cell-based assays
- (2008) Laurent Sansregret et al. GENE
- EVI1 recruits the histone methyltransferase SUV39H1 for transcription repression
- (2008) Francesca Cattaneo et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Genetics of therapy-related myelodysplasia and acute myeloid leukemia
- (2008) J Pedersen-Bjergaard et al. LEUKEMIA
- Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
- (2008) Benjamin L. Ebert et al. NATURE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now