The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.

Posttranscriptional regulation of gene networks by GU-rich elements and CELF proteins

(2014) Irina A. Vlasova et al.   RNA Biology

Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L

(2011) Faegheh Jafarifar et al.   EMBO JOURNAL

Autoregulatory Suppression of c-Myc by miR-185-3p

(2011) Jun-Ming Liao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cooperative Role of the RNA-Binding Proteins Hzf and HuR in p53 Activation

(2011) H. Nakamura et al.   MOLECULAR AND CELLULAR BIOLOGY

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

(2011) Neelanjan Mukherjee et al.   MOLECULAR CELL

lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements

(2011) Chenguang Gong et al.   NATURE

Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs

(2011) Kotb Abdelmohsen et al.   NUCLEIC ACIDS RESEARCH

The Impact of miRNA Target Sites in Coding Sequences and in 3′UTRs

(2011) Zhuo Fang et al.   PLoS One

p21WAF1/CIP1 Upregulation through the Stress Granule-Associated Protein CUGBP1 Confers Resistance to Bortezomib-Mediated Apoptosis

(2011) Cristina Gareau et al.   PLoS One

Global assessment of GU-rich regulatory content and function in the human transcriptome

(2011) Anason S. Halees et al.   RNA Biology

Quaking Regulates Hnrnpa1 Expression through Its 3′ UTR in Oligodendrocyte Precursor Cells

(2011) N. Ruth Zearfoss et al.   PLoS Genetics

5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage

(2010) J. Chen et al.   GENES & DEVELOPMENT

MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment

(2010) Francesco P. Marchese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-2 mRNA Stabilization upon PMA Stimulation Is Dependent on NF90-Ser647 Phosphorylation by Protein Kinase C I

(2010) P. Zhu et al.   JOURNAL OF IMMUNOLOGY

miRNAs in human cancer

(2010) Thalia A Farazi et al.   JOURNAL OF PATHOLOGY

Phosphorylation of Tristetraprolin by MK2 Impairs AU-Rich Element mRNA Decay by Preventing Deadenylase Recruitment

(2010) S. L. Clement et al.   MOLECULAR AND CELLULAR BIOLOGY

HuR Uses AUF1 as a Cofactor To Promote p16INK4 mRNA Decay

(2010) N. Chang et al.   MOLECULAR AND CELLULAR BIOLOGY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

A Pumilio-induced RNA structure switch in p27-3′ UTR controls miR-221 and miR-222 accessibility

(2010) Martijn Kedde et al.   NATURE CELL BIOLOGY

Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation

(2010) Stefania Millevoi et al.   NUCLEIC ACIDS RESEARCH

Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets

(2010) Irene Díaz-Moreno et al.   NUCLEIC ACIDS RESEARCH

RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability

(2010) S. J. Cho et al.   NUCLEIC ACIDS RESEARCH

The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability

(2010) Ariane Scoumanne et al.   NUCLEIC ACIDS RESEARCH

The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes

(2010) N Al-Souhibani et al.   ONCOGENE

Systematic Analysis of Cis-Elements in Unstable mRNAs Demonstrates that CUGBP1 Is a Key Regulator of mRNA Decay in Muscle Cells

(2010) Jerome E. Lee et al.   PLoS One

Known turnover and translation regulatory RNA-binding proteins interact with the 3’ UTR of SECIS-binding protein 2

(2010) Jodi Bubenik et al.   RNA Biology

hnRNP L binds to CA repeats in the 3′UTR of bcl-2 mRNA

(2009) Dong-Hyoung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The mRNA-Destabilizing Protein Tristetraprolin Is Suppressed in Many Cancers, Altering Tumorigenic Phenotypes and Patient Prognosis

(2009) S. E. Brennan et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

In vivo post-transcriptional regulation of CD154 in mouse CD4+ T cells

(2009) Stefano Vavassori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression

(2009) Jan Chemnitz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulation of Bcl-2 Expression by HuR in HL60 Leukemia Cells and A431 Carcinoma Cells

(2009) D. Ishimaru et al.   MOLECULAR CANCER RESEARCH

miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

(2009) Ashish Lal et al.   MOLECULAR CELL

Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex

(2009) Yongsheng Shi et al.   MOLECULAR CELL

Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding

(2009) Irene Díaz-Moreno et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif

(2009) Yuki Kuwano et al.   NUCLEIC ACIDS RESEARCH

Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteine

(2009) Lynda Latrèche et al.   NUCLEIC ACIDS RESEARCH

Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation

(2009) Wijdan Al-Ahmadi et al.   NUCLEIC ACIDS RESEARCH

The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element

(2009) A. Vilborg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

(2009) Z. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Translational control by cytoplasmic polyadenylation in Xenopus oocytes

(2008) Helois E. Radford et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

microRNA-122 stimulates translation of hepatitis C virus RNA

(2008) Jura Inga Henke et al.   EMBO JOURNAL

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Finishing touches: Post-translational modification of protein factors involved in mammalian pre-mRNA 3′ end formation

(2008) Kevin Ryan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Genome-wide Analysis Identifies Interleukin-10 mRNA as Target of Tristetraprolin

(2008) Georg Stoecklin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment

(2008) Roman Hrstka et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MKP-1 mRNA Stabilization and Translational Control by RNA-Binding Proteins HuR and NF90

(2008) Y. Kuwano et al.   MOLECULAR AND CELLULAR BIOLOGY

Conserved GU-Rich Elements Mediate mRNA Decay by Binding to CUG-Binding Protein 1

(2008) Irina A. Vlasova et al.   MOLECULAR CELL

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

A stress-responsive RNA switch regulates VEGFA expression

(2008) Partho Sarothi Ray et al.   NATURE

The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2

(2008) S. Maitra et al.   RNA

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE

Dual localization of the RNA binding protein CUGBP-1 to stress granule and perinucleolar compartment

(2007) Ken Fujimura et al.   EXPERIMENTAL CELL RESEARCH